Pinpointing a Mechanistic Switch Between Ketoreduction and “Ene” Reduction in Short‐Chain Dehydrogenases/Reductases

por Lygidakis, Antonios, Karuppiah, Vijaykumar, Hoeven, Robin, Ní Cheallaigh, Aisling, Leys, David, Gardiner, John M., Toogood, Helen S., Scrutton, Nigel S.
Publicado 2016

Pinpointing a Mechanistic Switch Between Ketoreduction and “Ene” Reduction in Short‐Chain Dehydrogenases/Reductases

por Lygidakis, Antonios, Karuppiah, Vijaykumar, Hoeven, Robin, Ní Cheallaigh, Aisling, Leys, David, Gardiner, John M., Toogood, Helen S., Scrutton, Nigel S.
Publicado 2016

The UbiX flavin prenyltransferase reaction mechanism resembles class I terpene cyclase chemistry

por Marshall, Stephen A., Payne, Karl A. P., Fisher, Karl, White, Mark D., Ní Cheallaigh, Aisling, Balaikaite, Arune, Rigby, Stephen E. J., Leys, David
Publicado 2019

Structural Basis of Catalysis in the Bacterial Monoterpene Synthases Linalool Synthase and 1,8-Cineole Synthase

por Karuppiah, Vijaykumar, Ranaghan, Kara E., Leferink, Nicole G. H., Johannissen, Linus O., Shanmugam, Muralidharan, Ní Cheallaigh, Aisling, Bennett, Nathan J., Kearsey, Lewis J., Takano, Eriko, Gardiner, John M., van der Kamp, Marc W., Hay, Sam, Mulholland, Adrian J., Leys, David, Scrutton, Nigel S.
Publicado 2017