Pre-clinical evaluation of antiproteases as potential candidates for HIV-1 pre-exposure prophylaxis

por Herrera, Carolina, Olejniczak, Natalia, Noël-Romas, Laura, Plummer, Frank, Burgener, Adam
Publicado 2022

Non-Lactobacillus-Dominant and Polymicrobial Vaginal Microbiomes Are More Common in Younger South African Women and Predictive of Increased Risk of Human Immunodeficiency Virus Acq...

por Wang, Yiran, Noël-Romas, Laura, Perner, Michelle, Knodel, Samantha, Molatlhegi, Refilwe, Hoger, Sarah, Birse, Kenzie, Zuend, Christina Farr, McKinnon, Lyle R, Burgener, Adam D
Publicado 2022

Influence of dapivirine vaginal ring use on cervicovaginal immunity and functional microbiome in adolescent girls

por Farr Zuend, Christina, Noël-Romas, Laura, Hoger, Sarah, McCorriser, Stuart, Westmacott, Garrett, Marrazzo, Jeanne, Hillier, Sharon L., Dezzutti, Charlene, Squires, Kathleen, Bunge, Katherine E., Burgener, Adam
Publicado 2021

Pregnancy associates with alterations to the host and microbial proteome in vaginal mucosa

por Farr Zuend, Christina, Tobin, Nicole H., Vera, Trisha, Kotyrba, Lani, Noël‐Romas, Laura, Birse, Kenzie, Mutch, Sarah, Li, Fan, Lee, David, McCorrister, Stuart, Westmacott, Garrett, Aldrovandi, Grace M., Burgener, Adam D.
Publicado 2020

Impact of Q-Griffithsin anti-HIV microbicide gel in non-human primates: In situ analyses of epithelial and immune cell markers in rectal mucosa

por Günaydın, Gökçe, Edfeldt, Gabriella, Garber, David A., Asghar, Muhammad, Noȅl-Romas, Laura, Burgener, Adam, Wählby, Carolina, Wang, Lin, Rohan, Lisa C., Guenthner, Patricia, Mitchell, James, Matoba, Nobuyuki, McNicholl, Janet M., Palmer, Kenneth E., Tjernlund, Annelie, Broliden, Kristina
Publicado 2019

Vaginal microbiome-hormonal contraceptive interactions associate with the mucosal proteome and HIV acquisition

por Noël-Romas, Laura, Perner, Michelle, Molatlhegi, Refilwe, Farr Zuend, Christina, Mabhula, Amanda, Hoger, Sarah, Lamont, Alana, Birse, Kenzie, Berard, Alicia, McCorrister, Stuart, Westmacott, Garett, Leslie, Al, Poliquin, Vanessa, Heffron, Renee, McKinnon, Lyle R., Burgener, Adam D.
Publicado 2020

Acute Infection and Subsequent Subclinical Reactivation of Herpes Simplex Virus 2 after Vaginal Inoculation of Rhesus Macaques

por Lo, Ming, Zhu, Jia, Hansen, Scott G., Carroll, Timothy, Farr Zuend, Christina, Nöel-Romas, Laura, Ma, Zhong-Min, Fritts, Linda, Huang, Meei-Li, Sun, Sijie, Huang, Ying, Koelle, David M., Picker, Louis J., Burgener, Adam, Corey, Lawrence, Miller, Christopher J.
Publicado 2019

The neovaginal microbiome of transgender women post-gender reassignment surgery

por Birse, Kenzie D., Kratzer, Kateryna, Zuend, Christina Farr, Mutch, Sarah, Noël-Romas, Laura, Lamont, Alana, Abou, Max, Jalil, Emilia, Veloso, Valdiléa, Grinsztejn, Beatriz, Friedman, Ruth Khalili, Broliden, Kristina, Bradley, Frideborg, Poliquin, Vanessa, Li, Fan, Yanavich, Carolyn, Burgener, Adam, Aldrovandi, Grace
Publicado 2020

Impact of the griffithsin anti-HIV microbicide and placebo gels on the rectal mucosal proteome and microbiome in non-human primates

por Girard, Lauren, Birse, Kenzie, Holm, Johanna B., Gajer, Pawel, Humphrys, Mike S., Garber, David, Guenthner, Patricia, Noël-Romas, Laura, Abou, Max, McCorrister, Stuart, Westmacott, Garrett, Wang, Lin, Rohan, Lisa C., Matoba, Nobuyuki, McNicholl, Janet, Palmer, Kenneth E., Ravel, Jacques, Burgener, Adam D.
Publicado 2018

Systems analysis reveals differential expression of endocervical genes in African women randomized to DMPA-IM, LNG implant or cu-IUD

por Gupta, Prachi Mehrotra, Balle, Christina, Tharp, Gregory K., Nelson, Sydney A., Gasper, Melanie A., Brown, Bryan, Alisoltani, Arghavan, Onono, Maricianah, Palanee-Phillips, Thesla, Nair, Gonsagrie, Ayele, Hosseana, Noel-Romas, Laura, Passmore, Jo-Ann S., Burgener, Adam D., Heffron, Renee, Jaspan, Heather B., Bosinger, Steven E.
Publicado 2023

Increased genital mucosal cytokines in Canadian women associate with higher antigen-presenting cells, inflammatory metabolites, epithelial barrier disruption, and the depletion of...

por Farr Zuend, Christina, Lamont, Alana, Noel-Romas, Laura, Knodel, Samantha, Birse, Kenzie, Kratzer, Kateryna, McQueen, Peter, Perner, Michelle, Ayele, Hossaena, Mutch, Sarah, Berard, Alicia R., Schellenberg, John J., Senturk, Faruk, McCorrister, Stuart, Westmacott, Garrett, Mulhall, Fran, Sandberg, Bonnie, Yu, Adelicia, Burnett, Margaret, Poliquin, Vanessa, Burgener, Adam D.
Publicado 2023

Initiating Intramuscular Depot Medroxyprogesterone Acetate Increases Frequencies of Th17-like Human Immunodeficiency Virus Target Cells in the Genital Tract of Women in South Afric...

por Bunjun, Rubina, Ramla, Tanko F, Jaumdally, Shameem Z, Noël-Romas, Laura, Ayele, Hossaena, Brown, Bryan P, Gamieldien, Hoyam, Harryparsad, Rushil, Dabee, Smritee, Nair, Gonasagrie, Onono, Maricianah, Palanee-Phillips, Thesla, Scoville, Catilin W, Heller, Kate B, Baeten, Jared M, Bosinger, Steven E, Burgener, Adam, Passmore, Jo-Ann S, Jaspan, Heather, Heffron, Renee
Publicado 2022

Vaginal epithelial dysfunction is mediated by the microbiome, metabolome, and mTOR signaling

por Berard, Alicia R., Brubaker, Douglas K., Birse, Kenzie, Lamont, Alana, Mackelprang, Romel D., Noël-Romas, Laura, Perner, Michelle, Hou, Xuanlin, Irungu, Elizabeth, Mugo, Nelly, Knodel, Samantha, Muwonge, Timothy R., Katabira, Elly, Hughes, Sean M., Levy, Claire, Calienes, Fernanda L., Lauffenburger, Douglas A., Baeten, Jared M., Celum, Connie, Hladik, Florian, Lingappa, Jairam, Burgener, Adam D.
Publicado 2023

Gut microbiome signatures linked to HIV-1 reservoir size and viremia control

por Borgognone, Alessandra, Noguera-Julian, Marc, Oriol, Bruna, Noël-Romas, Laura, Ruiz-Riol, Marta, Guillén, Yolanda, Parera, Mariona, Casadellà, Maria, Duran, Clara, Puertas, Maria C., Català-Moll, Francesc, De Leon, Marlon, Knodel, Samantha, Birse, Kenzie, Manzardo, Christian, Miró, José M., Clotet, Bonaventura, Martinez-Picado, Javier, Moltó, José, Mothe, Beatriz, Burgener, Adam, Brander, Christian, Paredes, Roger
Publicado 2022

Gut-derived bacterial toxins impair memory CD4(+) T cell mitochondrial function in HIV-1 infection

por Ferrari, Brian, Da Silva, Amanda Cabral, Liu, Ken H., Saidakova, Evgeniya V., Korolevskaya, Larisa B., Shmagel, Konstantin V., Shive, Carey, Pacheco Sanchez, Gabriela, Retuerto, Mauricio, Sharma, Ashish Arunkumar, Ghneim, Khader, Noel-Romas, Laura, Rodriguez, Benigno, Ghannoum, Mahmoud A., Hunt, Peter P., Deeks, Steven G., Burgener, Adam D., Jones, Dean P., Dobre, Mirela A., Marconi, Vincent C., Sekaly, Rafick-Pierre, Younes, Souheil-Antoine
Publicado 2022

Treatment with Commonly Used Antiretroviral Drugs Induces a Type I/III Interferon Signature in the Gut in the Absence of HIV Infection

por Hughes, Sean M., Levy, Claire N., Calienes, Fernanda L., Stekler, Joanne D., Pandey, Urvashi, Vojtech, Lucia, Berard, Alicia R., Birse, Kenzie, Noël-Romas, Laura, Richardson, Brian, Golden, Jackelyn B., Cartwright, Michael, Collier, Ann C., Stevens, Claire E., Curlin, Marcel E., Holtz, Timothy H., Mugo, Nelly, Irungu, Elizabeth, Katabira, Elly, Muwonge, Timothy, Lama, Javier R., Baeten, Jared M., Burgener, Adam, Lingappa, Jairam R., McElrath, M. Juliana, Mackelprang, Romel, McGowan, Ian, Cranston, Ross D., Cameron, Mark J., Hladik, Florian
Publicado 2020