Clinical evaluation of a fully automated, laboratory-developed multiplex RT-PCR assay integrating dual-target SARS-CoV-2 and influenza A/B detection on a high-throughput platform

por Nörz, Dominik, Hoffmann, Armin, Aepfelbacher, Martin, Pfefferle, Susanne, Lütgehetmann, Marc
Publicado 2021

Modifying a Diagnostic SARS-CoV-2 Spike PCR to Turn a Del69/70 Dropout into a Discriminatory On-Target Assay

por Nörz, Dominik, Pfefferle, Susanne, Grunwald, Moritz, Fischer, Nicole, Aepfelbacher, Martin, Lütgehetmann, Marc
Publicado 2021

Evaluation of a fully automated high-throughput SARS-CoV-2 multiplex qPCR assay with built-in screening functionality for del-HV69/70- and N501Y variants such as B.1.1.7

por Nörz, Dominik, Grunwald, Moritz, Olearo, Flaminia, Fischer, Nicole, Aepfelbacher, Martin, Pfefferle, Susanne, Lütgehetmann, Marc
Publicado 2021

Vertical Targeting of AKT and mTOR as Well as Dual Targeting of AKT and MEK Signaling Is Synergistic in Hepatocellular Carcinoma

por Ewald, Florian, Nörz, Dominik, Grottke, Astrid, Bach, Johanna, Herzberger, Christiane, Hofmann, Bianca T., Nashan, Björn, Jücker, Manfred
Publicado 2015

Clinical evaluation of a SARS-CoV-2 RT-PCR assay on a fully automated system for rapid on-demand testing in the hospital setting

por Nörz, Dominik, Fischer, Nicole, Schultze, Alexander, Kluge, Stefan, Mayer-Runge, Ulrich, Aepfelbacher, Martin, Pfefferle, Susanne, Lütgehetmann, Marc
Publicado 2020

Germany’s first COVID-19 deceased: a 59-year-old man presenting with diffuse alveolar damage due to SARS-CoV-2 infection

por Heinrich, Fabian, Sperhake, Jan-Peter, Heinemann, Axel, Mushumba, Herbert, Lennartz, Maximilian, Nörz, Dominik, Glatzel, Markus, Lütgehetmann, Marc, Püschel, Klaus
Publicado 2020

Multicenter Evaluation of a Fully Automated High-Throughput SARS-CoV-2 Antigen Immunoassay

por Nörz, Dominik, Olearo, Flaminia, Perisic, Stojan, Bauer, Matthias F., Riester, Elena, Schneider, Tanja, Schönfeld, Kathrin, Laengin, Tina, Lütgehetmann, Marc
Publicado 2021

Screening for Monkeypox Infection in Asymptomatic High-Risk-Behaviour Men Having Sex with Men (MSM)

por Pestel, Julia, Matthews, Hanna, Schmiedel, Stefan, Hüfner, Anja, Jordan, Sabine, Scheiter, Robin Luca, Lütgehetmann, Marc, Nörz, Dominik, Degen, Olaf
Publicado 2022

Complete Genome Sequence of a SARS-CoV-2 Strain Isolated in Northern Germany

por Pfefferle, Susanne, Huang, Jiabin, Nörz, Dominik, Indenbirken, Daniela, Lütgehetmann, Marc, Oestereich, Lisa, Günther, Thomas, Grundhoff, Adam, Aepfelbacher, Martin, Fischer, Nicole
Publicado 2020

Pushing beyond specifications: Evaluation of linearity and clinical performance of the cobas 6800/8800 SARS-CoV-2 RT-PCR assay for reliable quantification in blood and other materi...

por Nörz, Dominik, Frontzek, André, Eigner, Ulrich, Oestereich, Lisa, Wichmann, Dominic, Kluge, Stefan, Fischer, Nicole, Aepfelbacher, Martin, Pfefferle, Susanne, Lütgehetmann, Marc
Publicado 2020

The prevalence of early‐ and late‐onset bacterial, viral, and fungal respiratory superinfections in invasively ventilated COVID‐19 patients

por Paparoupa, Maria, Aldemyati, Razaz, Roggenkamp, Hannes, Berinson, Benjamin, Nörz, Dominik, Olearo, Flaminia, Kluge, Stefan, Roedl, Kevin, de Heer, Geraldine, Wichmann, Dominic
Publicado 2022

Detection of SARS-CoV-2 genomic and subgenomic RNA in retina and optic nerve of patients with COVID-19

por Casagrande, Maria, Fitzek, Antonia, Spitzer, Martin, Püschel, Klaus, Glatzel, Markus, Krasemann, Susanne, Aepfelbacher, Martin, Nörz, Dominik, Lütgehetmann, Marc, Pfefferle, Susanne, Schultheiss, Maximilian
Publicado 2022

Rapid Adaptation of Established High-Throughput Molecular Testing Infrastructure for Monkeypox Virus Detection

por Nörz, Dominik, Tang, Hui Ting, Emmerich, Petra, Giersch, Katja, Fischer, Nicole, Schmiedel, Stephan, Addo, Marylyn M., Aepfelbacher, Martin, Pfefferle, Susanne, Lütgehetmann, Marc
Publicado 2022

Postmortem Stability of SARS-CoV-2 in Nasopharyngeal Mucosa

por Heinrich, Fabian, Meißner, Kira, Langenwalder, Felicia, Püschel, Klaus, Nörz, Dominik, Hoffmann, Armin, Lütgehetmann, Marc, Aepfelbacher, Martin, Bibiza-Freiwald, Eric, Pfefferle, Susanne, Heinemann, Axel
Publicado 2021

Rapid Automated Screening for SARS-CoV-2 B.1.617 Lineage Variants (Delta/Kappa) through a Versatile Toolset of qPCR-Based SNP Detection

por Nörz, Dominik, Grunwald, Moritz, Tang, Hui Ting, Olearo, Flaminia, Günther, Thomas, Robitaille, Alexis, Fischer, Nicole, Grundhoff, Adam, Aepfelbacher, Martin, Pfefferle, Susanne, Lütgehetmann, Marc
Publicado 2021

Downregulation of AKT3 Increases Migration and Metastasis in Triple Negative Breast Cancer Cells by Upregulating S100A4

por Grottke, Astrid, Ewald, Florian, Lange, Tobias, Nörz, Dominik, Herzberger, Christiane, Bach, Johanna, Grabinski, Nicole, Gräser, Lareen, Höppner, Frank, Nashan, Björn, Schumacher, Udo, Jücker, Manfred
Publicado 2016

Infectivity of SARS-CoV-2 on Inanimate Surfaces: Don’t Trust Ct Value

por Knobloch, Johannes K., Pfefferle, Susanne, Lütgehetmann, Marc, Nörz, Dominik, Klupp, Eva M., Belmar Campos, Cristina E., Kluge, Stefan, Aepfelbacher, Martin, Knobling, Birte, Franke, Gefion
Publicado 2022

Viral Dynamics of SARS-CoV-2 in Critically Ill Allogeneic Hematopoietic Stem Cell Transplant Recipients and Immunocompetent Patients with COVID-19

por Roedl, Kevin, Heidenreich, Silke, Pfefferle, Susanne, Jarczak, Dominik, Urbanowicz, Tatiana Theresa, Nörz, Dominik, Aepfelbacher, Martin, Kröger, Nicolaus, Kluge, Stefan, Lütgehetmann, Marc, Christopeit, Maximilian, Wichmann, Dominic
Publicado 2021

Clinical Evaluation of a Fully-Automated High-Throughput Multiplex Screening-Assay to Detect and Differentiate the SARS-CoV-2 B.1.1.529 (Omicron) and B.1.617.2 (Delta) Lineage Vari...

por Nörz, Dominik, Grunwald, Moritz, Tang, Hui Ting, Weinschenk, Celine, Günther, Thomas, Robitaille, Alexis, Giersch, Katja, Fischer, Nicole, Grundhoff, Adam, Aepfelbacher, Martin, Pfefferle, Susanne, Lütgehetmann, Marc
Publicado 2022

New Postmortem Perspective on Emerging SARS-CoV-2 Variants of Concern, Germany

por Heinrich, Fabian, Huter, Tobias, Mertens, Sophie, Lange, Philine, Vering, Jessica, Heinemann, Axel, Nörz, Dominik Sebastian, Hoffmann, Armin, Aepfelbacher, Martin, Ondruschka, Benjamin, Krasemann, Susanne, Lütgehetmann, Marc
Publicado 2023