Genome-Wide Modulation of Gene Transcription in Ovarian Carcinoma Cells by a New Mithramycin Analogue

por Vizcaíno, Carolina, Núñez, Luz-Elena, Morís, Francisco, Portugal, José
Publicado 2014

Antitumoral activity of the mithralog EC-8042 in triple negative breast cancer linked to cell cycle arrest in G2

por Pandiella, Atanasio, Morís, Francisco, Ocaña, Alberto, Núñez, Luz-Elena, Montero, Juan C.
Publicado 2015

Mithramycin A and Mithralog EC-8042 Inhibit SETDB1 Expression and Its Oncogenic Activity in Malignant Melanoma

por Federico, Aniello, Steinfass, Tamara, Larribère, Lionel, Novak, Daniel, Morís, Francisco, Núñez, Luz-Elena, Umansky, Viktor, Utikal, Jochen
Publicado 2020

Modulation of the Activity of Sp Transcription Factors by Mithramycin Analogues as a New Strategy for Treatment of Metastatic Prostate Cancer

por Malek, Anastasia, Núñez, Luz-Elena, Magistri, Marco, Brambilla, Lara, Jovic, Sandra, Carbone, Giuseppina M., Morís, Francisco, Catapano, Carlo V.
Publicado 2012

The chromomycin CmmA acetyltransferase: a membrane‐bound enzyme as a tool for increasing structural diversity of the antitumour mithramycin

por García, Beatriz, González‐Sabín, Javier, Menéndez, Nuria, Braña, Alfredo F., Núñez, Luz Elena, Morís, Francisco, Salas, José A., Méndez, Carmen
Publicado 2011

Pleiotropic Anti-Angiogenic and Anti-Oncogenic Activities of the Novel Mithralog Demycarosyl-3D-ß-D-Digitoxosyl-Mithramycin SK (EC-8042)

por Fernández-Guizán, Azahara, López-Soto, Alejandro, Acebes-Huerta, Andrea, Huergo-Zapico, Leticia, Villa-Álvarez, Mónica, Núñez, Luz-Elena, Morís, Francisco, Gonzalez, Segundo
Publicado 2015

Phospho-kinase profile of colorectal tumors guides in the selection of multi-kinase inhibitors

por Serrano-Heras, Gemma, Cuenca-López, María Dolores, Montero, Juan Carlos, Corrales-Sanchez, Verónica, Morales, Jorge Carlos, Núñez, Luz-Elena, Morís, Francisco, Pandiella, Atanasio, Ocaña, Alberto
Publicado 2015

Inhibition of SP1 by the mithramycin analog EC-8042 efficiently targets tumor initiating cells in sarcoma

por Tornin, Juan, Martinez-Cruzado, Lucia, Santos, Laura, Rodriguez, Aida, Núñez, Luz-Elena, Oro, Patricia, Hermosilla, Maria Ana, Allonca, Eva, Fernández-García, Maria Teresa, Astudillo, Aurora, Suarez, Carlos, Morís, Francisco, Rodriguez, Rene
Publicado 2016

High-Quality Draft Genome Sequence of the Actinobacterium Nocardia terpenica IFM 0406, Producer of the Immunosuppressant Brasilicardins, Using Illumina and PacBio Technologies

por Buchmann, Anina, Eitel, Michael, Koch, Pierre, Schwarz, Paul N., Stegmann, Evi, Wohlleben, Wolfgang, Wolański, Marcin, Krawiec, Michał, Zakrzewska-Czerwińska, Jolanta, Méndez, Carmen, Botas, Alma, Núñez, Luz Elena, Morís, Francisco, Cortés, Jesus, Gross, Harald
Publicado 2016

A novel LysR‐type regulator negatively affects biosynthesis of the immunosuppressant brasilicardin

por Wolański, Marcin, Krawiec, Michał, Schwarz, Paul N., Stegmann, Evi, Wohlleben, Wolfgang, Buchmann, Anina, Gross, Harald, Eitel, Michael, Koch, Pierre, Botas, Alma, Méndez, Carmen, Núñez, Luz Elena, Morís, Francisco, Cortés, Jesus, Zakrzewska‐Czerwińska, Jolanta
Publicado 2020

The Mithralog EC-7072 Induces Chronic Lymphocytic Leukemia Cell Death by Targeting Tonic B-Cell Receptor Signaling

por Lorenzo-Herrero, Seila, Sordo-Bahamonde, Christian, Bretones, Gabriel, Payer, Ángel R., González-Rodríguez, Ana P., González-García, Esther, Pérez-Escuredo, Jhudit, Villa-Álvarez, Mónica, Núñez, Luz-Elena, Morís, Francisco, Gonzalez, Segundo, López-Soto, Alejandro
Publicado 2019

Antitumor activity of the novel multi-kinase inhibitor EC-70124 in triple negative breast cancer

por Cuenca-López, María Dolores, Serrano-Heras, Gemma, Montero, Juan Carlos, Corrales-Sánchez, Verónica, Gomez-Juarez, Mónica, Gascón-Escribano, Maria José, Carlos Morales, Jorge, Voisin, Veronique, Núñez, Luz Elena, Morís, Francisco, Bader, Gary D., Pandiella, Atanasio, Ocaña, Alberto
Publicado 2015

Genetic Engineering in Combination with Semi‐Synthesis Leads to a New Route for Gram‐Scale Production of the Immunosuppressive Natural Product Brasilicardin A

por Botas, Alma, Eitel, Michael, Schwarz, Paul N., Buchmann, Anina, Costales, Paula, Núñez, Luz Elena, Cortés, Jesús, Morís, Francisco, Krawiec, Michał, Wolański, Marcin, Gust, Bertolt, Rodriguez, Mirna, Fischer, Wolf‐Nicolas, Jandeleit, Bernd, Zakrzewska‐Czerwińska, Jolanta, Wohlleben, Wolfgang, Stegmann, Evi, Koch, Pierre, Méndez, Carmen, Gross, Harald
Publicado 2021