TLR3 Activation of Intratumoral CD103(+) Dendritic Cells Modifies the Tumor Infiltrate Conferring Anti-tumor Immunity

por Roselli, Emiliano, Araya, Paula, Núñez, Nicolás Gonzalo, Gatti, Gerardo, Graziano, Francesca, Sedlik, Christine, Benaroch, Philippe, Piaggio, Eliane, Maccioni, Mariana
Publicado 2019

Oxidation inhibits autophagy protein deconjugation from phagosomes to sustain MHC class II restricted antigen presentation

por Ligeon, Laure-Anne, Pena-Francesch, Maria, Vanoaica, Liliana Danusia, Núñez, Nicolás Gonzalo, Talwar, Deepti, Dick, Tobias P., Münz, Christian
Publicado 2021

Downregulation of adaptor protein MyD88 compromises the angiogenic potential of B16 murine melanoma

por Trucco, Lucas Daniel, Roselli, Emiliano, Araya, Paula, Nuñez, Nicolás Gonzalo, Mena, Hebe Agustina, Bocco, José Luis, Negrotto, Soledad, Maccioni, Mariana
Publicado 2017

Tumor cell-derived IL-10 promotes cell-autonomous growth and immune escape in diffuse large B-cell lymphoma

por Stirm, Kristin, Leary, Peter, Bertram, Katrin, Núñez, Nicolás Gonzalo, Wüst, Daria, Boudesco, Christophe, Verhoeyen, Els, Zenz, Thorsten, Becher, Burkhard, Menter, Thomas, Tzankov, Alexandar, Müller, Anne
Publicado 2021

TGF-β production by eosinophils drives the expansion of peripherally induced neuropilin(−) RORγt(+) regulatory T-cells during bacterial and allergen challenge

por Fallegger, Angela, Priola, Martina, Artola-Borán, Mariela, Núñez, Nicolás Gonzalo, Wild, Sebastian, Gurtner, Alessandra, Becher, Burkhard, Yousefi, Shida, Simon, Hans-Uwe, Arnold, Isabelle C., Müller, Anne
Publicado 2022

Immunological Predictors of Dimethyl Fumarate‐Induced Lymphopenia

por Diebold, Martin, Galli, Edoardo, Kopf, Andreas, Sanderson, Nicholas, Callegari, Ilaria, Ingelfinger, Florian, Núñez, Nicolás Gonzalo, Benkert, Pascal, Kappos, Ludwig, Kuhle, Jens, Becher, Burkhard, Claassen, Manfred, Derfuss, Tobias
Publicado 2022

Lymph node invasion by tumor cells modifies the distribution of dendritic cell subsets and memory T cell profiles in human cancer patients

por Núñez, Nicolás Gonzalo, Nadan, Ana Tereza, Pérol, Louis, Milder, Maud, Viel, Sophie, De La Rochere Philippe, Philippe, Loirat, Delphine, Xavier, Sastre-Garau, Sedlik, Christine, Amigorena, Sebastian, Piaggio, Eliane
Publicado 2014

Phenotype of NK-Like CD8(+) T Cells with Innate Features in Humans and Their Relevance in Cancer Diseases

por Barbarin, Alice, Cayssials, Emilie, Jacomet, Florence, Nunez, Nicolas Gonzalo, Basbous, Sara, Lefèvre, Lucie, Abdallah, Myriam, Piccirilli, Nathalie, Morin, Benjamin, Lavoue, Vincent, Catros, Véronique, Piaggio, Eliane, Herbelin, André, Gombert, Jean-Marc
Publicado 2017

Induction of anergic or regulatory tumor-specific CD4(+) T cells in the tumor-draining lymph node

por Alonso, Ruby, Flament, Héloïse, Lemoine, Sébastien, Sedlik, Christine, Bottasso, Emanuel, Péguillet, Isabel, Prémel, Virginie, Denizeau, Jordan, Salou, Marion, Darbois, Aurélie, Núñez, Nicolás Gonzalo, Salomon, Benoit, Gross, David, Piaggio, Eliane, Lantz, Olivier
Publicado 2018

Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy

por Georganaki, Maria, Ramachandran, Mohanraj, Tuit, Sander, Núñez, Nicolás Gonzalo, Karampatzakis, Alexandros, Fotaki, Grammatiki, van Hooren, Luuk, Huang, Hua, Lugano, Roberta, Ulas, Thomas, Kaunisto, Aura, Holland, Eric C, Ellmark, Peter, Mangsbo, Sara M, Schultze, Joachim, Essand, Magnus, Tugues, Sonia, Dimberg, Anna
Publicado 2020

Tumor invasion in draining lymph nodes is associated with Treg accumulation in breast cancer patients

por Núñez, Nicolas Gonzalo, Tosello Boari, Jimena, Ramos, Rodrigo Nalio, Richer, Wilfrid, Cagnard, Nicolas, Anderfuhren, Cyrill Dimitri, Niborski, Leticia Laura, Bigot, Jeremy, Meseure, Didier, De La Rochere, Philippe, Milder, Maud, Viel, Sophie, Loirat, Delphine, Pérol, Louis, Vincent-Salomon, Anne, Sastre-Garau, Xavier, Burkhard, Becher, Sedlik, Christine, Lantz, Olivier, Amigorena, Sebastian, Piaggio, Eliane
Publicado 2020

Loss of immune tolerance to IL-2 in type 1 diabetes

por Pérol, Louis, Lindner, John M., Caudana, Pamela, Nunez, Nicolas Gonzalo, Baeyens, Audrey, Valle, Andrea, Sedlik, Christine, Loirat, Delphine, Boyer, Olivier, Créange, Alain, Cohen, José Laurent, Rogner, Ute Christine, Yamanouchi, Jun, Marchant, Martine, Leber, Xavier Charles, Scharenberg, Meike, Gagnerault, Marie-Claude, Mallone, Roberto, Battaglia, Manuela, Santamaria, Pere, Hartemann, Agnès, Traggiai, Elisabetta, Piaggio, Eliane
Publicado 2016

Distinct immunological signatures discriminate severe COVID-19 from non-SARS-CoV-2-driven critical pneumonia

por Kreutmair, Stefanie, Unger, Susanne, Núñez, Nicolás Gonzalo, Ingelfinger, Florian, Alberti, Chiara, De Feo, Donatella, Krishnarajah, Sinduya, Kauffmann, Manuel, Friebel, Ekaterina, Babaei, Sepideh, Gaborit, Benjamin, Lutz, Mirjam, Jurado, Nicole Puertas, Malek, Nisar P., Goepel, Siri, Rosenberger, Peter, Häberle, Helene A., Ayoub, Ikram, Al-Hajj, Sally, Nilsson, Jakob, Claassen, Manfred, Liblau, Roland, Martin-Blondel, Guillaume, Bitzer, Michael, Roquilly, Antoine, Becher, Burkhard
Publicado 2021

Distinct immunological signatures discriminate severe COVID-19 from non-SARS-CoV-2-driven critical pneumonia

por Kreutmair, Stefanie, Unger, Susanne, Núñez, Nicolás Gonzalo, Ingelfinger, Florian, Alberti, Chiara, De Feo, Donatella, Krishnarajah, Sinduya, Kauffmann, Manuel, Friebel, Ekaterina, Babaei, Sepideh, Gaborit, Benjamin, Lutz, Mirjam, Jurado, Nicole Puertas, Malek, Nisar P., Goepel, Siri, Rosenberger, Peter, Häberle, Helene A., Ayoub, Ikram, Al-Hajj, Sally, Nilsson, Jakob, Claassen, Manfred, Liblau, Roland, Martin-Blondel, Guillaume, Bitzer, Michael, Roquilly, Antoine, Becher, Burkhard
Publicado 2022

Preexisting comorbidities shape the immune response associated with severe COVID-19

por Kreutmair, Stefanie, Kauffmann, Manuel, Unger, Susanne, Ingelfinger, Florian, Núñez, Nicolás Gonzalo, Alberti, Chiara, De Feo, Donatella, Krishnarajah, Sinduya, Friebel, Ekaterina, Ulutekin, Can, Babaei, Sepideh, Gaborit, Benjamin, Lutz, Mirjam, Jurado, Nicole Puertas, Malek, Nisar P., Göpel, Siri, Rosenberger, Peter, Häberle, Helene A., Ayoub, Ikram, Al-Hajj, Sally, Claassen, Manfred, Liblau, Roland, Martin-Blondel, Guillaume, Bitzer, Michael, Roquilly, Antoine, Becher, Burkhard
Publicado 2022

Heterogeneity of response to immune checkpoint blockade in hypermutated experimental gliomas

por Aslan, Katrin, Turco, Verena, Blobner, Jens, Sonner, Jana K., Liuzzi, Anna Rita, Núñez, Nicolás Gonzalo, De Feo, Donatella, Kickingereder, Philipp, Fischer, Manuel, Green, Ed, Sadik, Ahmed, Friedrich, Mirco, Sanghvi, Khwab, Kilian, Michael, Cichon, Frederik, Wolf, Lara, Jähne, Kristine, von Landenberg, Anna, Bunse, Lukas, Sahm, Felix, Schrimpf, Daniel, Meyer, Jochen, Alexander, Allen, Brugnara, Gianluca, Röth, Ralph, Pfleiderer, Kira, Niesler, Beate, von Deimling, Andreas, Opitz, Christiane, Breckwoldt, Michael O., Heiland, Sabine, Bendszus, Martin, Wick, Wolfgang, Becher, Burkhard, Platten, Michael
Publicado 2020

High-dimensional analysis of 16 SARS-CoV-2 vaccine combinations reveals lymphocyte signatures correlating with immunogenicity

por Nuñez, Nicolás Gonzalo, Schmid, Jonas, Power, Laura, Alberti, Chiara, Krishnarajah, Sinduya, Kreutmair, Stefanie, Unger, Susanne, Blanco, Sebastián, Konigheim, Brenda, Marín, Constanza, Onofrio, Luisina, Kienzler, Jenny Christine, Costa-Pereira, Sara, Ingelfinger, Florian, Pasinovich, Marina E., Castelli, Juan M., Vizzotti, Carla, Schaefer, Maximilian, Villar-Vesga, Juan, Mundt, Sarah, Merten, Carla Helena, Sethi, Aakriti, Wertheimer, Tobias, Lutz, Mirjam, Vanoaica, Danusia, Sotomayor, Claudia, Gruppi, Adriana, Münz, Christian, Cardozo, Diego, Barbás, Gabriela, Lopez, Laura, Carreño, Paula, Castro, Gonzalo, Raboy, Elias, Gallego, Sandra, Morón, Gabriel, Cervi, Laura, Acosta Rodriguez, Eva V., Maletto, Belkys A., Maccioni, Mariana, Becher, Burkhard
Publicado 2023

NASH limits anti-tumour surveillance in immunotherapy-treated HCC

por Pfister, Dominik, Núñez, Nicolás Gonzalo, Pinyol, Roser, Govaere, Olivier, Pinter, Matthias, Szydlowska, Marta, Gupta, Revant, Qiu, Mengjie, Deczkowska, Aleksandra, Weiner, Assaf, Müller, Florian, Sinha, Ankit, Friebel, Ekaterina, Engleitner, Thomas, Lenggenhager, Daniela, Moncsek, Anja, Heide, Danijela, Stirm, Kristin, Kosla, Jan, Kotsiliti, Eleni, Leone, Valentina, Dudek, Michael, Yousuf, Suhail, Inverso, Donato, Singh, Indrabahadur, Teijeiro, Ana, Castet, Florian, Montironi, Carla, Haber, Philipp K., Tiniakos, Dina, Bedossa, Pierre, Cockell, Simon, Younes, Ramy, Vacca, Michele, Marra, Fabio, Schattenberg, Jörn M., Allison, Michael, Bugianesi, Elisabetta, Ratziu, Vlad, Pressiani, Tiziana, D’Alessio, Antonio, Personeni, Nicola, Rimassa, Lorenza, Daly, Ann K., Scheiner, Bernhard, Pomej, Katharina, Kirstein, Martha M., Vogel, Arndt, Peck-Radosavljevic, Markus, Hucke, Florian, Finkelmeier, Fabian, Waidmann, Oliver, Trojan, Jörg, Schulze, Kornelius, Wege, Henning, Koch, Sandra, Weinmann, Arndt, Bueter, Marco, Rössler, Fabian, Siebenhüner, Alexander, De Dosso, Sara, Mallm, Jan-Philipp, Umansky, Viktor, Jugold, Manfred, Luedde, Tom, Schietinger, Andrea, Schirmacher, Peter, Emu, Brinda, Augustin, Hellmut G., Billeter, Adrian, Müller-Stich, Beat, Kikuchi, Hiroto, Duda, Dan G., Kütting, Fabian, Waldschmidt, Dirk-Thomas, Ebert, Matthias Philip, Rahbari, Nuh, Mei, Henrik E., Schulz, Axel Ronald, Ringelhan, Marc, Malek, Nisar, Spahn, Stephan, Bitzer, Michael, Ruiz de Galarreta, Marina, Lujambio, Amaia, Dufour, Jean-Francois, Marron, Thomas U., Kaseb, Ahmed, Kudo, Masatoshi, Huang, Yi-Hsiang, Djouder, Nabil, Wolter, Katharina, Zender, Lars, Marche, Parice N., Decaens, Thomas, Pinato, David J., Rad, Roland, Mertens, Joachim C., Weber, Achim, Unger, Kristian, Meissner, Felix, Roth, Susanne, Jilkova, Zuzana Macek, Claassen, Manfred, Anstee, Quentin M., Amit, Ido, Knolle, Percy, Becher, Burkhard, Llovet, Josep M., Heikenwalder, Mathias
Publicado 2021