Development of novel drug delivery systems using phage display technology for clinical application of protein drugs

por NAGANO, Kazuya, TSUTSUMI, Yasuo
Publicado 2016

Phage Display Technology as a Powerful Platform for Antibody Drug Discovery

por Nagano, Kazuya, Tsutsumi, Yasuo
Publicado 2021

Tor-Mediated Induction of Autophagy via an Apg1 Protein Kinase Complex

por Kamada, Yoshiaki, Funakoshi, Tomoko, Shintani, Takahiro, Nagano, Kazuya, Ohsumi, Mariko, Ohsumi, Yoshinori
Publicado 2000

Evaluation of silica nanoparticle binding to major human blood proteins

por Hata, Katsutomo, Higashisaka, Kazuma, Nagano, Kazuya, Mukai, Yohei, Kamada, Haruhiko, Tsunoda, Shin-ichi, Yoshioka, Yasuo, Tsutsumi, Yasuo
Publicado 2014

A Novel Bispecific Antibody against Human CD3 and Ephrin Receptor A10 for Breast Cancer Therapy

por Taki, Shintaro, Kamada, Haruhiko, Inoue, Masaki, Nagano, Kazuya, Mukai, Yohei, Higashisaka, Kazuma, Yoshioka, Yasuo, Tsutsumi, Yasuo, Tsunoda, Shin-ichi
Publicado 2015

Creation of mouse TNFR2-selective agonistic TNF mutants using a phage display technique

por Ando, Daisuke, Inoue, Masaki, Kamada, Haruhiko, Taki, Shintaro, Furuya, Takeshi, Abe, Yasuhiro, Nagano, Kazuya, Tsutsumi, Yasuo, Tsunoda, Shin-ichi
Publicado 2016

Progesterone receptor membrane component 1 leads to erlotinib resistance, initiating crosstalk of Wnt/β-catenin and NF-κB pathways, in lung adenocarcinoma cells

por Lin, Ying, Higashisaka, Kazuma, Shintani, Takuya, Maki, Ayaka, Hanamuro, Sachiyo, Haga, Yuya, Maeda, Shinichiro, Tsujino, Hirofumi, Nagano, Kazuya, Fujio, Yasushi, Tsutsumi, Yasuo
Publicado 2020

Size and surface modification of amorphous silica particles determine their effects on the activity of human CYP3A4 in vitro

por Imai, Shunji, Yoshioka, Yasuo, Morishita, Yuki, Yoshida, Tokuyuki, Uji, Miyuki, Nagano, Kazuya, Mukai, Yohei, Kamada, Haruhiko, Tsunoda, Shin-ichi, Higashisaka, Kazuma, Tsutsumi, Yasuo
Publicado 2014

Optimization and Evaluation of Pretreatment Method for sp-ICP-MS to Reveal the Distribution of Silver Nanoparticles in the Body

por Ishizaka, Takuya, Nagano, Kazuya, Tasaki, Ikkei, Tao, Hong, Gao, Jian-Qing, Harada, Kazuo, Hirata, Kazumasa, Saito, Shigeru, Tsujino, Hirofumi, Higashisaka, Kazuma, Tsutsumi, Yasuo
Publicado 2019

Development and Evaluation of a System for the Semi-Quantitative Determination of the Physical Properties of Skin After Exposure to Silver Nanoparticles

por Tao, Hong, Nagano, Kazuya, Tasaki, Ikkei, Zhang, Tian-qi, Ishizaka, Takuya, Gao, Jian-Qing, Harada, Kazuo, Hirata, Kazumasa, Tsujino, Hirofumi, Higashisaka, Kazuma, Tsutsumi, Yasuo
Publicado 2020

Neutrophil Depletion Exacerbates Pregnancy Complications, Including Placental Damage, Induced by Silica Nanoparticles in Mice

por Higashisaka, Kazuma, Nakashima, Akitoshi, Iwahara, Yuki, Aoki, Aiko, Nakayama, Masahiro, Yanagihara, Itaru, Lin, Ying, Nagano, Kazuya, Tsunoda, Shin-ichi, Saito, Shigeru, Yoshioka, Yasuo, Tsutsumi, Yasuo
Publicado 2018

Expression of Eph receptor A10 is correlated with lymph node metastasis and stage progression in breast cancer patients

por Nagano, Kazuya, Kanasaki, So-ichiro, Yamashita, Takuya, Maeda, Yuka, Inoue, Masaki, Higashisaka, Kazuma, Yoshioka, Yasuo, Abe, Yasuhiro, Mukai, Yohei, Kamada, Haruhiko, Tsutsumi, Yasuo, Tsunoda, Shin-ichi
Publicado 2013

Autophagy is a new protective mechanism against the cytotoxicity of platinum nanoparticles in human trophoblasts

por Nakashima, Akitoshi, Higashisaka, Kazuma, Kusabiraki, Tae, Aoki, Aiko, Ushijima, Akemi, Ono, Yosuke, Tsuda, Sayaka, Shima, Tomoko, Yoshino, Osamu, Nagano, Kazuya, Yoshioka, Yasuo, Tsutsumi, Yasuo, Saito, Shigeru
Publicado 2019

Potential Suppressive Effects of Two C(60) Fullerene Derivatives on Acquired Immunity

por Hirai, Toshiro, Yoshioka, Yasuo, Udaka, Asako, Uemura, Eiichiro, Ohe, Tomoyuki, Aoshima, Hisae, Gao, Jian-Qing, Kokubo, Ken, Oshima, Takumi, Nagano, Kazuya, Higashisaka, Kazuma, Mashino, Tadahiko, Tsutsumi, Yasuo
Publicado 2016

Effect of surface properties of silica nanoparticles on their cytotoxicity and cellular distribution in murine macrophages

por Nabeshi, Hiromi, Yoshikawa, Tomoaki, Arimori, Akihiro, Yoshida, Tokuyuki, Tochigi, Saeko, Hirai, Toshiro, Akase, Takanori, Nagano, Kazuya, Abe, Yasuhiro, Kamada, Haruhiko, Tsunoda, Shin-ichi, Itoh, Norio, Yoshioka, Yasuo, Tsutsumi, Yasuo
Publicado 2011

Intranasal exposure to amorphous nanosilica particles could activate intrinsic coagulation cascade and platelets in mice

por Yoshida, Tokuyuki, Yoshioka, Yasuo, Tochigi, Saeko, Hirai, Toshiro, Uji, Miyuki, Ichihashi, Ko-ichi, Nagano, Kazuya, Abe, Yasuhiro, Kamada, Haruhiko, Tsunoda, Shin-ichi, Nabeshi, Hiromi, Higashisaka, Kazuma, Yoshikawa, Tomoaki, Tsutsumi, Yasuo
Publicado 2013

Amorphous nanosilica induce endocytosis-dependent ROS generation and DNA damage in human keratinocytes

por Nabeshi, Hiromi, Yoshikawa, Tomoaki, Matsuyama, Keigo, Nakazato, Yasutaro, Tochigi, Saeko, Kondoh, Sayuri, Hirai, Toshiro, Akase, Takanori, Nagano, Kazuya, Abe, Yasuhiro, Yoshioka, Yasuo, Kamada, Haruhiko, Itoh, Norio, Tsunoda, Shin-ichi, Tsutsumi, Yasuo
Publicado 2011

Promotion of allergic immune responses by intranasally-administrated nanosilica particles in mice

por Yoshida, Tokuyuki, Yoshioka, Yasuo, Fujimura, Maho, Yamashita, Kohei, Higashisaka, Kazuma, Morishita, Yuki, Kayamuro, Hiroyuki, Nabeshi, Hiromi, Nagano, Kazuya, Abe, Yasuhiro, Kamada, Haruhiko, Tsunoda, Shin-ichi, Itoh, Norio, Yoshikawa, Tomoaki, Tsutsumi, Yasuo
Publicado 2011

Hemopexin as biomarkers for analyzing the biological responses associated with exposure to silica nanoparticles

por Higashisaka, Kazuma, Yoshioka, Yasuo, Yamashita, Kohei, Morishita, Yuki, Pan, Huiyan, Ogura, Toshinobu, Nagano, Takashi, Kunieda, Akiyoshi, Nagano, Kazuya, Abe, Yasuhiro, Kamada, Haruhiko, Tsunoda, Shin-ichi, Nabeshi, Hiromi, Yoshikawa, Tomoaki, Tsutsumi, Yasuo
Publicado 2012

Intestinal absorption and biological effects of orally administered amorphous silica particles

por Yoshida, Tokuyuki, Yoshioka, Yasuo, Takahashi, Hideki, Misato, Kazuki, Mori, Takahide, Hirai, Toshiro, Nagano, Kazuya, Abe, Yasuhiro, Mukai, Yohei, Kamada, Haruhiko, Tsunoda, Shin-ichi, Nabeshi, Hiromi, Yoshikawa, Tomoaki, Higashisaka, Kazuma, Tsutsumi, Yasuo
Publicado 2014