Selective cell cycle arrest and induction of apoptosis in human prostate cancer cells by a polyphenol-rich extract of Solanum nigrum

por NAWAB, AKBAR, THAKUR, VIJAY S., YUNUS, MOHAMMAD, MAHDI, ABBAS ALI, GUPTA, SANJAY
Publicado 2012

Green Tea Polyphenols Induce p53-Dependent and p53-Independent Apoptosis in Prostate Cancer Cells through Two Distinct Mechanisms

por Gupta, Karishma, Thakur, Vijay S., Bhaskaran, Natarajan, Nawab, Akbar, Babcook, Melissa A., Jackson, Mark W., Gupta, Sanjay
Publicado 2012

Tsc1 Regulates the Proliferation Capacity of Bone-Marrow Derived Mesenchymal Stem Cells

por Guijarro, Maria V., Danielson, Laura S., Cañamero, Marta, Nawab, Akbar, Abrahan, Carolina, Hernando, Eva, Palmer, Glyn D.
Publicado 2020

TYMS promotes genomic instability and tumor progression in Ink4a/Arf null background

por Guijarro, Maria V., Nawab, Akbar, Dib, Peter, Burkett, Sandra, Luo, Xiaoping, Feely, Michael, Nasri, Elham, Seifert, Robert P., Kaye, Frederic J., Zajac-Kaye, Maria
Publicado 2023

Oxidative Stress and Antioxidant Status in High-Risk Prostate Cancer Subjects

por Shukla, Sanjeev, Srivastava, Janmejai K., Shankar, Eswar, Kanwal, Rajnee, Nawab, Akbar, Sharma, Haripaul, Bhaskaran, Natarajan, Ponsky, Lee E., Fu, Pingfu, MacLennan, Gregory T., Gupta, Sanjay
Publicado 2020

NSC30049 inhibits Chk1 pathway in 5-FU-resistant CRC bulk and stem cell populations

por Narayan, Satya, Jaiswal, Aruna S., Sharma, Ritika, Nawab, Akbar, Duckworth, Lizette Vila, Law, Brian K., Zajac-Kaye, Maria, George, Thomas J., Sharma, Jay, Sharma, Arun K., Hromas, Robert A.
Publicado 2017

Thymidylate synthase accelerates Men1-mediated pancreatic tumor progression and reduces survival

por Vijayakurup, Vinod, Maeng, Kyungah, Lee, Hye Seung, Meyer, Benjamin, Burkett, Sandra, Nawab, Akbar, Dougherty, Michael W., Jobin, Christian, Mahmud, Iqbal, Garrett, Timothy J., Feely, Michael, Lee, Kyoung Bun, Kaye, Frederic J., Guijarro, Maria V., Zajac-Kaye, Maria
Publicado 2022

Targeting Thymidylate Synthase Enhances the Chemosensitivity of Triple-Negative Breast Cancer Towards 5-FU-Based Combinatorial Therapy

por Haritha, Nair Hariprasad, Nawab, Akbar, Vijayakurup, Vinod, Anto, Nikhil Ponnoor, Liju, Vijayasteltar B., Alex, Vijai V., Amrutha, Areekkara Nisthul, Aiswarya, Sreekumar U., Swetha, Mundanattu, Vinod, Balachandran S., Sundaram, Sankar, Guijarro, Maria V., Herlevich, Thomas, Krishna, Archana, Nestory, Nesteena K., Bava, Smitha V., Sadasivan, Chittalakkottu, Zajac-Kaye, Maria, Anto, Ruby John
Publicado 2021

First-in-class multifunctional TYMS nonclassical antifolate inhibitor with potent in vivo activity that prolongs survival

por Guijarro, Maria V., Kellish, Patrick C., Dib, Peter E., Paciaroni, Nicholas G., Nawab, Akbar, Andring, Jacob, Kulemina, Lidia, Borrero, Nicholas V., Modenutti, Carlos, Feely, Michael, Nasri, Elham, Seifert, Robert P., Luo, Xiaoping, Bennett, Richard L., Shabashvili, Daniil, Licht, Jonathan D., McKenna, Robert, Roitberg, Adrian, Huigens, Robert W., Kaye, Frederic J., Zajac-Kaye, Maria
Publicado 2023