A Live-Attenuated Prime, Inactivated Boost Vaccination Strategy with Chimeric Hemagglutinin-Based Universal Influenza Virus Vaccines Provides Protection in Ferrets: A Confirmatory...

por Nachbagauer, Raffael, Krammer, Florian, Albrecht, Randy A.
Publicado 2018

Cross-reactive mouse monoclonal antibodies raised against the hemagglutinin of A/Shanghai/1/2013 (H7N9) protect against novel H7 virus isolates in the mouse model

por Stadlbauer, Daniel, Amanat, Fatima, Strohmeier, Shirin, Nachbagauer, Raffael, Krammer, Florian
Publicado 2018

Age Dependence and Isotype Specificity of Influenza Virus Hemagglutinin Stalk-Reactive Antibodies in Humans

por Nachbagauer, Raffael, Choi, Angela, Izikson, Ruvim, Cox, Manon M., Palese, Peter, Krammer, Florian
Publicado 2016

An Influenza Virus Hemagglutinin-Based Vaccine Platform Enables the Generation of Epitope Specific Human Cytomegalovirus Antibodies

por Behzadi, Mohammad Amin, Stein, Kathryn R., Bermúdez-González, Maria Carolina, Simon, Viviana, Nachbagauer, Raffael, Tortorella, Domenico
Publicado 2019

A cross-reactive mouse monoclonal antibody against rhinovirus mediates phagocytosis in vitro

por Behzadi, Mohammad Amin, Choi, Angela, Duehr, James, Feyznezhad, Roya, Upadhyay, Chitra, Schotsaert, Michael, Palese, Peter, Nachbagauer, Raffael
Publicado 2020

A mosaic hemagglutinin-based influenza virus vaccine candidate protects mice from challenge with divergent H3N2 strains

por Broecker, Felix, Liu, Sean T. H., Suntronwong, Nungruthai, Sun, Weina, Bailey, Mark J., Nachbagauer, Raffael, Krammer, Florian, Palese, Peter
Publicado 2019

Hemagglutinin Stalk Antibody Responses Following Trivalent Inactivated Influenza Vaccine Immunization of Pregnant Women and Association With Protection From Influenza Virus Illness

por Dhar, Nisha, Kwatra, Gaurav, Nunes, Marta C, Cutland, Clare, Izu, Alane, Nachbagauer, Raffael, Krammer, Florian, Madhi, Shabir A
Publicado 2020

An immuno-assay to quantify influenza virus hemagglutinin with correctly folded stalk domains in vaccine preparations

por Rajendran, Madhusudan, Sun, Weina, Comella, Phillip, Nachbagauer, Raffael, Wohlbold, Teddy John, Amanat, Fatima, Kirkpatrick, Ericka, Palese, Peter, Krammer, Florian
Publicado 2018

Influenza Virus Hemagglutinin Stalk-Specific Antibodies in Human Serum are a Surrogate Marker for In Vivo Protection in a Serum Transfer Mouse Challenge Model

por Jacobsen, Henning, Rajendran, Madhusudan, Choi, Angela, Sjursen, Haakon, Brokstad, Karl A., Cox, Rebecca J., Palese, Peter, Krammer, Florian, Nachbagauer, Raffael
Publicado 2017

Vaccination with Adjuvanted Recombinant Neuraminidase Induces Broad Heterologous, but Not Heterosubtypic, Cross-Protection against Influenza Virus Infection in Mice

por Wohlbold, Teddy John, Nachbagauer, Raffael, Xu, Haoming, Tan, Gene S., Hirsh, Ariana, Brokstad, Karl A., Cox, Rebecca J., Palese, Peter, Krammer, Florian
Publicado 2015

Globular Head-Displayed Conserved Influenza H1 Hemagglutinin Stalk Epitopes Confer Protection against Heterologous H1N1 Virus

por Klausberger, Miriam, Tscheliessnig, Rupert, Neff, Silke, Nachbagauer, Raffael, Wohlbold, Teddy John, Wilde, Monika, Palmberger, Dieter, Krammer, Florian, Jungbauer, Alois, Grabherr, Reingard
Publicado 2016

Analysis of Anti-Influenza Virus Neuraminidase Antibodies in Children, Adults, and the Elderly by ELISA and Enzyme Inhibition: Evidence for Original Antigenic Sin

por Rajendran, Madhusudan, Nachbagauer, Raffael, Ermler, Megan E., Bunduc, Paul, Amanat, Fatima, Izikson, Ruvim, Cox, Manon, Palese, Peter, Eichelberger, Maryna, Krammer, Florian
Publicado 2017

A chimeric haemagglutinin-based influenza split virion vaccine adjuvanted with AS03 induces protective stalk-reactive antibodies in mice

por Nachbagauer, Raffael, Kinzler, David, Choi, Angela, Hirsh, Ariana, Beaulieu, Edith, Lecrenier, Nicolas, Innis, Bruce L, Palese, Peter, Mallett, Corey P, Krammer, Florian
Publicado 2016

Vaccination with a Recombinant H7 Hemagglutinin-Based Influenza Virus Vaccine Induces Broadly Reactive Antibodies in Humans

por Stadlbauer, Daniel, Rajabhathor, Arvind, Amanat, Fatima, Kaplan, Daniel, Masud, Abusaleh, Treanor, John J., Izikson, Ruvim, Cox, Manon M., Nachbagauer, Raffael, Krammer, Florian
Publicado 2017

Sequential Immunization With Live-Attenuated Chimeric Hemagglutinin-Based Vaccines Confers Heterosubtypic Immunity Against Influenza A Viruses in a Preclinical Ferret Model

por Liu, Wen-Chun, Nachbagauer, Raffael, Stadlbauer, Daniel, Solórzano, Alicia, Berlanda-Scorza, Francesco, García-Sastre, Adolfo, Palese, Peter, Krammer, Florian, Albrecht, Randy A.
Publicado 2019

Broadly Neutralizing Hemagglutinin Stalk-Specific Antibodies Induce Potent Phagocytosis of Immune Complexes by Neutrophils in an Fc-Dependent Manner

por Mullarkey, Caitlin E., Bailey, Mark J., Golubeva, Diana A., Tan, Gene S., Nachbagauer, Raffael, He, Wenqian, Novakowski, Kyle E., Bowdish, Dawn M., Miller, Matthew S., Palese, Peter
Publicado 2016

Targeting Antigen to the Surface of EVs Improves the In Vivo Immunogenicity of Human and Non-human Adenoviral Vaccines in Mice

por Bliss, Carly M., Parsons, Andrea J., Nachbagauer, Raffael, Hamilton, Jennifer R., Cappuccini, Federica, Ulaszewska, Marta, Webber, Jason P., Clayton, Aled, Hill, Adrian V.S., Coughlan, Lynda
Publicado 2019

Cryo-electron Microscopy Structures of Chimeric Hemagglutinin Displayed on a Universal Influenza Vaccine Candidate

por Tran, Erin E. H., Podolsky, Kira A., Bartesaghi, Alberto, Kuybeda, Oleg, Grandinetti, Giovanna, Wohlbold, Teddy John, Tan, Gene S., Nachbagauer, Raffael, Palese, Peter, Krammer, Florian, Subramaniam, Sriram
Publicado 2016

Influenza Virus Infection Induces a Narrow Antibody Response in Children but a Broad Recall Response in Adults

por Meade, Philip, Kuan, Guillermina, Strohmeier, Shirin, Maier, Hannah E., Amanat, Fatima, Balmaseda, Angel, Ito, Kimihito, Kirkpatrick, Ericka, Javier, Andres, Gresh, Lionel, Nachbagauer, Raffael, Gordon, Aubree, Krammer, Florian
Publicado 2020

Chimeric Hemagglutinin-Based Live-Attenuated Vaccines Confer Durable Protective Immunity against Influenza A Viruses in a Preclinical Ferret Model

por Liu, Wen-Chun, Nachbagauer, Raffael, Stadlbauer, Daniel, Strohmeier, Shirin, Solórzano, Alicia, Berlanda-Scorza, Francesco, Innis, Bruce L., García-Sastre, Adolfo, Palese, Peter, Krammer, Florian, Albrecht, Randy A.
Publicado 2021