BRCA1 intronic Alu elements drive gene rearrangements and PARP inhibitor resistance

por Wang, Yifan, Bernhardy, Andrea J., Nacson, Joseph, Krais, John J., Tan, Yin-Fei, Nicolas, Emmanuelle, Radke, Marc R., Handorf, Elizabeth, Llop-Guevara, Alba, Balmaña, Judith, Swisher, Elizabeth M., Serra, Violeta, Peri, Suraj, Johnson, Neil
Publicado 2019

Genetic separation of Brca1 functions reveal mutation-dependent Polθ vulnerabilities

por Krais, John J., Glass, David J., Chudoba, Ilse, Wang, Yifan, Feng, Wanjuan, Simpson, Dennis, Patel, Pooja, Liu, Zemin, Neumann-Domer, Ryan, Betsch, Robert G., Bernhardy, Andrea J., Bradbury, Alice M., Conger, Jason, Yueh, Wei-Ting, Nacson, Joseph, Pomerantz, Richard T., Gupta, Gaorav P., Testa, Joseph R., Johnson, Neil
Publicado 2023

BRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance

por Nacson, Joseph, Krais, John J., Bernhardy, Andrea J., Clausen, Emma, Feng, Wanjuan, Wang, Yifan, Nicolas, Emmanuelle, Cai, Kathy Q., Tricarico, Rossella, Hua, Xiang, DiMarcantonio, Daniela, Martinez, Esteban, Zong, Dali, Handorf, Elizabeth A., Bellacosa, Alfonso, Testa, Joseph R., Nussenzweig, Andre, Gupta, Gaorav P., Sykes, Stephen M., Johnson, Neil
Publicado 2018