Eliminating or blocking 12/15-lipoxygenase reduces neutrophil recruitment in mouse models of acute lung injury

por Rossaint, Jan, Nadler, Jerry L, Ley, Klaus, Zarbock, Alexander
Publicado 2012

Interleukin-12 (IL-12)/STAT4 Axis Is an Important Element for β-Cell Dysfunction Induced by Inflammatory Cytokines

por Weaver, Jessica R., Nadler, Jerry L., Taylor-Fishwick, David A.
Publicado 2015

Regulation of Tissue Inflammation by 12-Lipoxygenases

por Kulkarni, Abhishek, Nadler, Jerry L., Mirmira, Raghavendra G., Casimiro, Isabel
Publicado 2021

The AAV-PCSK9 murine model of atherosclerosis and metabolic dysfunction

por Keeter, William Coles, Carter, Nigeste M, Nadler, Jerry L, Galkina, Elena V
Publicado 2022

Adipose Tissue-Specific Deletion of 12/15-Lipoxygenase Protects Mice from the Consequences of a High-Fat Diet

por Cole, Banumathi K., Morris, Margaret A., Grzesik, Wojciech J., Leone, Kendall A., Nadler, Jerry L.
Publicado 2012

Proteomic Analysis of Disease Stratified Human Pancreas Tissue Indicates Unique Signature of Type 1 Diabetes

por Burch, Tanya C., Morris, Margaret A., Campbell-Thompson, Martha, Pugliese, Alberto, Nadler, Jerry L., Nyalwidhe, Julius O.
Publicado 2015

Neutrophil-specific STAT4 deficiency attenuates atherosclerotic burden and improves plaque stability via reduction in neutrophil activation and recruitment into aortas of Ldlr(−/−)...

por Keeter, W. Coles, Moriarty, Alina K., Akers, Rachel, Ma, Shelby, Mussbacher, Marion, Nadler, Jerry L., Galkina, Elena V.
Publicado 2023

Neutrophil-specific STAT4 deficiency attenuates atherosclerotic burden and improves plaque stability via reduction in neutrophil activation and recruitment into aortas of Ldlr(−/−)...

por Keeter, W. Coles, Moriarty, Alina K, Akers, Rachel, Ma, Shelby, Mussbacher, Marion, Nadler, Jerry L., Galkina, Elena V.
Publicado 2023

Key Role of STAT4 Deficiency in the Hematopoietic Compartment in Insulin Resistance and Adipose Tissue Inflammation

por Dobrian, Anca D., Ma, Kaiwen, Glenn, Lindsey M., Hatcher, Margaret A., Haynes, Bronson A., Lehrer, Eric J., Kaplan, Mark H., Nadler, Jerry L.
Publicado 2017

Insulin and glucose play a role in foam cell formation and function

por Shashkin, Pavel N, Jain, Nitin, Miller, Yury I, Rissing, Benjamin A, Huo, Yuqing, Keller, Susanna R, Vandenhoff, George E, Nadler, Jerry L, McIntyre, Thomas M
Publicado 2006

Comparative quantitative proteomic analysis of disease stratified laser captured microdissected human islets identifies proteins and pathways potentially related to type 1 diabetes

por Nyalwidhe, Julius O., Grzesik, Wojciech J., Burch, Tanya C., Semeraro, Michele L., Waseem, Tayab, Gerling, Ivan C., Mirmira, Raghavendra G., Morris, Margaret A., Nadler, Jerry L.
Publicado 2017

STAT4 Deficiency Reduces Obesity-Induced Insulin Resistance and Adipose Tissue Inflammation

por Dobrian, Anca D., Galkina, Elena V., Ma, Qian, Hatcher, Margaret, Aye, Sabai Myo, Butcher, Mathew J., Ma, Kaiwen, Haynes, Bronson A., Kaplan, Mark H., Nadler, Jerry L.
Publicado 2013

Coxsackievirus-Induced Proteomic Alterations in Primary Human Islets Provide Insights for the Etiology of Diabetes

por Nyalwidhe, Julius O., Gallagher, Glen R., Glenn, Lindsey M., Morris, Margaret A., Vangala, Pranitha, Jurczyk, Agata, Bortell, Rita, Harlan, David M., Wang, Jennifer P., Nadler, Jerry L.
Publicado 2017

Host Factors Alter Effects of Angiopoietin-Like Protein 8 on Glucose Homeostasis in Diabetic Mice

por Liu, Sichen, Smith, Emily M., King, Timothy H., Glenn, Lindsey, Trevino, Michelle, Park, So Hyun, Machida, Yui, Villaflor, Ciriaco, Grzesik, Wojciech, Morris, Margaret A., Imai, Yumi, Nadler, Jerry L.
Publicado 2016

Myeloid cell deficiency of the inflammatory transcription factor Stat4 protects long-term synaptic plasticity from the effects of a high-fat, high-cholesterol diet

por Zhang, Xiao-lei, Hollander, Callie M., Khan, Mohammad Yasir, D’silva, Melinee, Ma, Haoqin, Yang, Xinyuan, Bai, Robin, Keeter, Coles K., Galkina, Elena V., Nadler, Jerry L., Stanton, Patric K.
Publicado 2023

STAT4 is expressed in neutrophils and promotes antimicrobial immunity

por Mehrpouya-Bahrami, Pegah, Moriarty, Alina K., De Melo, Paulo, Keeter, W. Coles, Alakhras, Nada S., Nelson, Andrew S., Hoover, Madeline, Barrios, Maria S., Nadler, Jerry L., Serezani, C. Henrique, Kaplan, Mark H., Galkina, Elena V.
Publicado 2021

12-Lipoxygenase governs the innate immune pathogenesis of islet inflammation and autoimmune diabetes

por Kulkarni, Abhishek, Pineros, Annie R., Walsh, Melissa A., Casimiro, Isabel, Ibrahim, Sara, Hernandez-Perez, Marimar, Orr, Kara S., Glenn, Lindsey, Nadler, Jerry L., Morris, Margaret A., Tersey, Sarah A., Mirmira, Raghavendra G., Anderson, Ryan M.
Publicado 2021

Inhibition of 12/15-Lipoxygenase Protects Against β-Cell Oxidative Stress and Glycemic Deterioration in Mouse Models of Type 1 Diabetes

por Hernandez-Perez, Marimar, Chopra, Gaurav, Fine, Jonathan, Conteh, Abass M., Anderson, Ryan M., Linnemann, Amelia K., Benjamin, Chanelle, Nelson, Jennifer B., Benninger, Kara S., Nadler, Jerry L., Maloney, David J., Tersey, Sarah A., Mirmira, Raghavendra G.
Publicado 2017

Proteomic and Transcriptional Profiles of Human Stem Cell-Derived β Cells Following Enteroviral Challenge

por Nyalwidhe, Julius O., Jurczyk, Agata, Satish, Basanthi, Redick, Sambra, Qaisar, Natasha, Trombly, Melanie I., Vangala, Pranitha, Racicot, Riccardo, Bortell, Rita, Harlan, David M., Greiner, Dale L., Brehm, Michael A., Nadler, Jerry L., Wang, Jennifer P.
Publicado 2020

Complement Activation and STAT4 Expression Are Associated with Early Inflammation in Diabetic Wounds

por Cunnion, Kenji M., Krishna, Neel K., Pallera, Haree K., Pineros-Fernandez, Angela, Rivera, Magdielis Gregory, Hair, Pamela S., Lassiter, Brittany P., Huyck, Ryan, Clements, Mary A., Hood, Antoinette F., Rodeheaver, George T., Cottler, Patrick S., Nadler, Jerry L., Dobrian, Anca D.
Publicado 2017