The Influenza Virus Polymerase Complex: An Update on Its Structure, Functions, and Significance for Antiviral Drug Design

por Stevaert, Annelies, Naesens, Lieve
Publicado 2016

Airway proteases: an emerging drug target for influenza and other respiratory virus infections

por Laporte, Manon, Naesens, Lieve
Publicado 2017

Editorial overview: Antiviral strategies: Antiviral drug design: creating new ideas against old and new bugs

por Naesens, Lieve, Zoulim, Fabien
Publicado 2017

Nucleoside analogs for management of respiratory virus infections: mechanism of action and clinical efficacy

por Stevaert, Annelies, Groaz, Elisabetta, Naesens, Lieve
Publicado 2022

Interaction between Mouse Adenovirus Type 1 and Cell Surface Heparan Sulfate Proteoglycans

por Lenaerts, Liesbeth, van Dam, Wim, Persoons, Leentje, Naesens, Lieve
Publicado 2012

Design and synthesis of novel Imidazo[2,1-b]thiazole derivatives as potent antiviral and antimycobacterial agents

por Gürsoy, Elif, Dincel, Efe Doğukan, Naesens, Lieve, Ulusoy Güzeldemirci, Nuray
Publicado 2020

Synthesis and antiviral evaluation of acyclic azanucleosides developed from sulfanilamide as a lead structure

por Gawin, Rafał, De Clercq, Erik, Naesens, Lieve, Koszytkowska-Stawińska, Mariola
Publicado 2008

Synthesis and Biological Evaluation of Novel (thio)semicarbazone-Based Benzimidazoles as Antiviral Agents against Human Respiratory Viruses

por Francesconi, Valeria, Cichero, Elena, Schenone, Silvia, Naesens, Lieve, Tonelli, Michele
Publicado 2020

Cidofovir selectivity is based on the different response of normal and cancer cells to DNA damage

por De Schutter, Tim, Andrei, Graciela, Topalis, Dimitri, Naesens, Lieve, Snoeck, Robert
Publicado 2013

Cidofovir is active against human papillomavirus positive and negative head and neck and cervical tumor cells by causing DNA damage as one of its working mechanisms

por Mertens, Barbara, Nogueira, Tatiane, Stranska, Ruzena, Naesens, Lieve, Andrei, Graciela, Snoeck, Robert
Publicado 2016

Synthesis and antiviral properties of novel indole-based thiosemicarbazides and 4-thiazolidinones

por Cihan-Üstündağ, Gökçe, Gürsoy, Elif, Naesens, Lieve, Ulusoy-Güzeldemirci, Nuray, Çapan, Gültaze
Publicado 2016

Application of the phosphoramidate ProTide approach to the antiviral drug ribavirin

por Derudas, Marco, Brancale, Andrea, Naesens, Lieve, Neyts, Johan, Balzarini, Jan, McGuigan, Christopher
Publicado 2010

Facile synthesis, antimicrobial and antiviral evaluation of novel substituted phenyl 1,3-thiazolidin-4-one sulfonyl derivatives

por Mandal, Milan Kumar, Ghosh, Swagatika, Naesens, Lieve, Bhat, Hans Raj, Singh, Udaya Pratap
Publicado 2021

First discovery of novel 3-hydroxy-quinazoline-2,4(1H,3H)-diones as specific anti-vaccinia and adenovirus agents via ‘privileged scaffold’ refining approach

por Kang, Dongwei, Zhang, Heng, Zhou, Zhongxia, Huang, Boshi, Naesens, Lieve, Zhan, Peng, Liu, Xinyong
Publicado 2016

Reprogramming of the Antibacterial Drug Vancomycin Results in Potent Antiviral Agents Devoid of Antibacterial Activity

por Szűcs, Zsolt, Naesens, Lieve, Stevaert, Annelies, Ostorházi, Eszter, Batta, Gyula, Herczegh, Pál, Borbás, Anikó
Publicado 2020

Crystal structures and inhibition of Trypanosoma brucei hypoxanthine–guanine phosphoribosyltransferase

por Terán, David, Hocková, Dana, Česnek, Michal, Zíková, Alena, Naesens, Lieve, Keough, Dianne T., Guddat, Luke W.
Publicado 2016

Design, synthesis, antitubercular and antiviral properties of new spirocyclic indole derivatives

por Cihan-Üstündağ, Gökçe, Naesens, Lieve, Şatana, Dilek, Erköse-Genç, Gonca, Mataracı-Kara, Emel, Çapan, Gültaze
Publicado 2019

Ritter reaction-mediated syntheses of 2-oxaadamantan-5-amine, a novel amantadine analog

por Leiva, Rosana, Gazzarrini, Sabrina, Esplugas, Roser, Moroni, Anna, Naesens, Lieve, Sureda, Francesc X., Vázquez, Santiago
Publicado 2015

Synthesis, biological evaluation and molecular modeling of novel azaspiro dihydrotriazines as influenza virus inhibitors targeting the host factor dihydrofolate reductase (DHFR)

por Francesconi, Valeria, Giovannini, Luca, Santucci, Matteo, Cichero, Elena, Costi, Maria Paola, Naesens, Lieve, Giordanetto, Fabrizio, Tonelli, Michele
Publicado 2018

Impact of SARS-CoV-2 Spike Mutations on Its Activation by TMPRSS2 and the Alternative TMPRSS13 Protease

por Stevaert, Annelies, Van Berwaer, Ria, Mestdagh, Cato, Vandeput, Julie, Vanstreels, Els, Raeymaekers, Valerie, Laporte, Manon, Naesens, Lieve
Publicado 2022