scMEGA: single-cell multi-omic enhancer-based gene regulatory network inference

por Li, Zhijian, Nagai, James S, Kuppe, Christoph, Kramann, Rafael, Costa, Ivan G
Publicado 2023

CrossTalkeR: analysis and visualization of ligand–receptorne tworks

por Nagai, James S, Leimkühler, Nils B, Schaub, Michael T, Schneider, Rebekka K, Costa, Ivan G
Publicado 2021

A stomata classification and detection system in microscope images of maize cultivars

por Aono, Alexandre H., Nagai, James S., Dickel, Gabriella da S. M., Marinho, Rafaela C., de Oliveira, Paulo E. A. M., Papa, João P., Faria, Fabio A.
Publicado 2021

Comparison of methods and resources for cell-cell communication inference from single-cell RNA-Seq data

por Dimitrov, Daniel, Türei, Dénes, Garrido-Rodriguez, Martin, Burmedi, Paul L., Nagai, James S., Boys, Charlotte, Ramirez Flores, Ricardo O., Kim, Hyojin, Szalai, Bence, Costa, Ivan G., Valdeolivas, Alberto, Dugourd, Aurélien, Saez-Rodriguez, Julio
Publicado 2022

Mapping the cardiac vascular niche in heart failure

por Peisker, Fabian, Halder, Maurice, Nagai, James, Ziegler, Susanne, Kaesler, Nadine, Hoeft, Konrad, Li, Ronghui, Bindels, Eric M. J., Kuppe, Christoph, Moellmann, Julia, Lehrke, Michael, Stoppe, Christian, Schaub, Michael T., Schneider, Rebekka K., Costa, Ivan, Kramann, Rafael
Publicado 2022

S205: INHIBITING THE ALARMIN-DRIVEN HEMATOPOIESIS-STROMAL CELLS CROSSTALK IN PRIMARY MYELOFIBROSIS AMELIORATES BONE MARROW FIBROSIS

por Gleitz, Hélène, Snoeren, Inge, Fuchs, Stijn, Nagai, James, Dugourd, Aurélien, Boys, Charlotte, Klöker, Vanessa, Pritchard, Jessica, Bindels, Eric, Te Boekhorst, Peter André Willem, Crysandt, Martina, Saez-Rodriguez, Julio, Vogl, Thomas, Kramann, Rafael, Costa, Ivan, Schneider, Rebekka
Publicado 2023

Enhanced fatty acid oxidation through Metformin and Baicalin as therapy for COVID-19 and associated inflammatory states in lung and kidney

por Miguel, Verónica, Rey-Serra, Carlos, Tituaña, Jessica, Sirera, Belén, Herrero, J. Ignacio, Ranz, Irene, Fernández, Laura, Castillo, Carolina, Sevilla, Lucía, Nagai, James, Reimer, Katharina C., Jansen, Jitske, Kramann, Rafael, Costa, Ivan G., Castro, Ana, Rodríguez González-Moro, José Miguel, Lamas, Santiago
Publicado 2023

Machine learning approaches reveal genomic regions associated with sugarcane brown rust resistance

por Aono, Alexandre Hild, Costa, Estela Araujo, Rody, Hugo Vianna Silva, Nagai, James Shiniti, Pimenta, Ricardo José Gonzaga, Mancini, Melina Cristina, dos Santos, Fernanda Raquel Camilo, Pinto, Luciana Rossini, Landell, Marcos Guimarães de Andrade, de Souza, Anete Pereira, Kuroshu, Reginaldo Massanobu
Publicado 2020

Enhanced fatty acid oxidation through metformin and baicalin as therapy for COVID-19 and associated inflammatory states in lung and kidney

por Miguel, Verónica, Rey-Serra, Carlos, Tituaña, Jessica, Sirera, Belén, Alcalde-Estévez, Elena, Herrero, J. Ignacio, Ranz, Irene, Fernández, Laura, Castillo, Carolina, Sevilla, Lucía, Nagai, James, Reimer, Katharina C., Jansen, Jitske, Kramann, Rafael, Costa, Ivan G., Castro, Ana, Sancho, David, Rodríguez González-Moro, José Miguel, Lamas, Santiago
Publicado 2023

Platelet-instructed SPP1(+) macrophages drive myofibroblast activation in fibrosis in a CXCL4-dependent manner

por Hoeft, Konrad, Schaefer, Gideon J.L., Kim, Hyojin, Schumacher, David, Bleckwehl, Tore, Long, Qingqing, Klinkhammer, Barbara Mara, Peisker, Fabian, Koch, Lars, Nagai, James, Halder, Maurice, Ziegler, Susanne, Liehn, Elisa, Kuppe, Christoph, Kranz, Jennifer, Menzel, Sylvia, Costa, Ivan, Wahida, Adam, Boor, Peter, Schneider, Rebekka K., Hayat, Sikander, Kramann, Rafael
Publicado 2023

Mapping cardiac remodeling in chronic kidney disease

por Kaesler, Nadine, Cheng, Mingbo, Nagai, James, O’Sullivan, James, Peisker, Fabian, Bindels, Eric M. J., Babler, Anne, Moellmann, Julia, Droste, Patrick, Franciosa, Giulia, Dugourd, Aurelien, Saez-Rodriguez, Julio, Neuss, Sabine, Lehrke, Michael, Boor, Peter, Goettsch, Claudia, Olsen, Jesper V., Speer, Thimoteus, Lu, Tzong-Shi, Lim, Kenneth, Floege, Jürgen, Denby, Laura, Costa, Ivan, Kramann, Rafael
Publicado 2023

Dissecting CD8+ T cell pathology of severe SARS-CoV-2 infection by single-cell immunoprofiling

por Schreibing, Felix, Hannani, Monica T., Kim, Hyojin, Nagai, James S., Ticconi, Fabio, Fewings, Eleanor, Bleckwehl, Tore, Begemann, Matthias, Torow, Natalia, Kuppe, Christoph, Kurth, Ingo, Kranz, Jennifer, Frank, Dario, Anslinger, Teresa M., Ziegler, Patrick, Kraus, Thomas, Enczmann, Jürgen, Balz, Vera, Windhofer, Frank, Balfanz, Paul, Kurts, Christian, Marx, Gernot, Marx, Nikolaus, Dreher, Michael, Schneider, Rebekka K., Saez-Rodriguez, Julio, Costa, Ivan, Hayat, Sikander, Kramann, Rafael
Publicado 2022

Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axis

por Leimkühler, Nils B., Gleitz, Hélène F.E., Ronghui, Li, Snoeren, Inge A.M., Fuchs, Stijn N.R., Nagai, James S., Banjanin, Bella, Lam, King H., Vogl, Thomas, Kuppe, Christoph, Stalmann, Ursula S.A., Büsche, Guntram, Kreipe, Hans, Gütgemann, Ines, Krebs, Philippe, Banz, Yara, Boor, Peter, Tai, Evelyn Wing-Yin, Brümmendorf, Tim H., Koschmieder, Steffen, Crysandt, Martina, Bindels, Eric, Kramann, Rafael, Costa, Ivan G., Schneider, Rebekka K.
Publicado 2021

The Wild Sugarcane and Sorghum Kinomes: Insights Into Expansion, Diversification, and Expression Patterns

por Aono, Alexandre Hild, Pimenta, Ricardo José Gonzaga, Garcia, Ana Letycia Basso, Correr, Fernando Henrique, Hosaka, Guilherme Kenichi, Carrasco, Marishani Marin, Cardoso-Silva, Cláudio Benício, Mancini, Melina Cristina, Sforça, Danilo Augusto, dos Santos, Lucas Borges, Nagai, James Shiniti, Pinto, Luciana Rossini, Landell, Marcos Guimarães de Andrade, Carneiro, Monalisa Sampaio, Balsalobre, Thiago Willian, Quiles, Marcos Gonçalves, Pereira, Welison Andrade, Margarido, Gabriel Rodrigues Alves, de Souza, Anete Pereira
Publicado 2021

Human pluripotent stem cell-derived kidney organoids for personalized congenital and idiopathic nephrotic syndrome modeling

por Jansen, Jitske, van den Berge, Bartholomeus T., van den Broek, Martijn, Maas, Rutger J., Daviran, Deniz, Willemsen, Brigith, Roverts, Rona, van der Kruit, Marit, Kuppe, Christoph, Reimer, Katharina C., Di Giovanni, Gianluca, Mooren, Fieke, Nlandu, Quincy, Mudde, Helmer, Wetzels, Roy, den Braanker, Dirk, Parr, Naomi, Nagai, James S., Drenic, Vedran, Costa, Ivan G., Steenbergen, Eric, Nijenhuis, Tom, Dijkman, Henry, Endlich, Nicole, van de Kar, Nicole C. A. J., Schneider, Rebekka K., Wetzels, Jack F. M., Akiva, Anat, van der Vlag, Johan, Kramann, Rafael, Schreuder, Michiel F., Smeets, Bart
Publicado 2022

Adult human kidney organoids originate from CD24(+) cells and represent an advanced model for adult polycystic kidney disease

por Xu, Yaoxian, Kuppe, Christoph, Perales-Patón, Javier, Hayat, Sikander, Kranz, Jennifer, Abdallah, Ali T., Nagai, James, Li, Zhijian, Peisker, Fabian, Saritas, Turgay, Halder, Maurice, Menzel, Sylvia, Hoeft, Konrad, Kenter, Annegien, Kim, Hyojin, van Roeyen, Claudia R. C., Lehrke, Michael, Moellmann, Julia, Speer, Thimoteus, Buhl, Eva M., Hoogenboezem, Remco, Boor, Peter, Jansen, Jitske, Knopp, Cordula, Kurth, Ingo, Smeets, Bart, Bindels, Eric, Reinders, Marlies E. J., Baan, Carla, Gribnau, Joost, Hoorn, Ewout J., Steffens, Joachim, Huber, Tobias B, Costa, Ivan, Floege, Jürgen, Schneider, Rebekka K., Saez-Rodriguez, Julio, Freedman, Benjamin S., Kramann, Rafael
Publicado 2022

Spatial multi-omic map of human myocardial infarction

por Kuppe, Christoph, Ramirez Flores, Ricardo O., Li, Zhijian, Hayat, Sikander, Levinson, Rebecca T., Liao, Xian, Hannani, Monica T., Tanevski, Jovan, Wünnemann, Florian, Nagai, James S., Halder, Maurice, Schumacher, David, Menzel, Sylvia, Schäfer, Gideon, Hoeft, Konrad, Cheng, Mingbo, Ziegler, Susanne, Zhang, Xiaoting, Peisker, Fabian, Kaesler, Nadine, Saritas, Turgay, Xu, Yaoxian, Kassner, Astrid, Gummert, Jan, Morshuis, Michiel, Amrute, Junedh, Veltrop, Rogier J. A., Boor, Peter, Klingel, Karin, Van Laake, Linda W., Vink, Aryan, Hoogenboezem, Remco M., Bindels, Eric M. J., Schurgers, Leon, Sattler, Susanne, Schapiro, Denis, Schneider, Rebekka K., Lavine, Kory, Milting, Hendrik, Costa, Ivan G., Saez-Rodriguez, Julio, Kramann, Rafael
Publicado 2022

SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids

por Jansen, Jitske, Reimer, Katharina C., Nagai, James S., Varghese, Finny S., Overheul, Gijs J., de Beer, Marit, Roverts, Rona, Daviran, Deniz, Fermin, Liline A.S., Willemsen, Brigith, Beukenboom, Marcel, Djudjaj, Sonja, von Stillfried, Saskia, van Eijk, Larissa E., Mastik, Mirjam, Bulthuis, Marian, Dunnen, Wilfred den, van Goor, Harry, Hillebrands, Jan-Luuk, Triana, Sergio H., Alexandrov, Theodore, Timm, Marie-Cherelle, van den Berge, Bartholomeus T., van den Broek, Martijn, Nlandu, Quincy, Heijnert, Joelle, Bindels, Eric M.J., Hoogenboezem, Remco M., Mooren, Fieke, Kuppe, Christoph, Miesen, Pascal, Grünberg, Katrien, Ijzermans, Ties, Steenbergen, Eric J., Czogalla, Jan, Schreuder, Michiel F., Sommerdijk, Nico, Akiva, Anat, Boor, Peter, Puelles, Victor G., Floege, Jürgen, Huber, Tobias B., van Rij, Ronald P., Costa, Ivan G., Schneider, Rebekka K., Smeets, Bart, Kramann, Rafael
Publicado 2022