Population pharmacokinetic analysis of RO5459072, a low water‐soluble drug exhibiting complex food–drug interactions

por Kratochwil, Nicole A., Stillhart, Cordula, Diack, Cheikh, Nagel, Sandra, Al Kotbi, Nada, Frey, Nicolas
Publicado 2021

Pharmacodynamic Monitoring of RO5459072, a Small Molecule Inhibitor of Cathepsin S

por Theron, Michel, Bentley, Darren, Nagel, Sandra, Manchester, Marianne, Gerg, Michael, Schindler, Thomas, Silva, Ana, Ecabert, Barbara, Teixeira, Priscila, Perret, Camille, Reis, Bernhard
Publicado 2017

A randomized, double‐blind phase 1b study evaluating the safety, tolerability, pharmacokinetics and pharmacodynamics of the NLRP3 inhibitor selnoflast in patients with moderate to...

por Klughammer, Barbara, Piali, Luca, Nica, Alexandra, Nagel, Sandra, Bailey, Lorna, Jochum, Christoph, Ignatenko, Stanislav, Bläuer, Angela, Danilin, Sabrina, Gulati, Pratiksha, Hayward, Joanne, Scepanovic, Petar, Zhang, Jitao David, Bhosale, Satish, Chong, Chui Fung, Christ, Andreas
Publicado 2023

Safety and Efficacy of Tocilizumab 4 or 8 mg/kg in Hospitalized Patients With Moderate to Severe Coronavirus Disease 2019 Pneumonia: A Randomized Clinical Trial

por Kumar, Princy N, Hernández-Sánchez, Jules, Nagel, Sandra, Feng, Yuning, Cai, Fang, Rabin, Joseph, Morse, Caryn G, Nadig, Nandita R, Ashraf, Obaid, Gotur, Deepa B, McComsey, Grace A, Gafoor, Khalid, Perin, Patrick, Thornton, Sarah C, Stubbings, William, Lin, Celia J F, Tsai, Larry
Publicado 2021