Solution‐Based Determination of Dissociation Constants for the Binding of Aβ42 to Antibodies

por Zhang, Tao, Nagel‐Steger, Luitgard, Willbold, Dieter
Publicado 2019

Interference with Amyloid-β Nucleation by Transient Ligand Interaction

por Zhang, Tao, Loschwitz, Jennifer, Strodel, Birgit, Nagel-Steger, Luitgard, Willbold, Dieter
Publicado 2019

Amyloid β Oligomeric Species Present in the Lag Phase of Amyloid Formation

por Wolff, Martin, Unuchek, Dmitry, Zhang, Bo, Gordeliy, Valentin, Willbold, Dieter, Nagel-Steger, Luitgard
Publicado 2015

Immobilization of Homogeneous Monomeric, Oligomeric and Fibrillar Aβ Species for Reliable SPR Measurements

por Frenzel, Daniel, Glück, Julian M., Brener, Oleksandr, Oesterhelt, Filipp, Nagel-Steger, Luitgard, Willbold, Dieter
Publicado 2014

Monomeric Amyloid Beta Peptide in Hexafluoroisopropanol Detected by Small Angle Neutron Scattering

por Zhang-Haagen, Bo, Biehl, Ralf, Nagel-Steger, Luitgard, Radulescu, Aurel, Richter, Dieter, Willbold, Dieter
Publicado 2016

Met/Val129 polymorphism of the full-length human prion protein dictates distinct pathways of amyloid formation

por Pauly, Thomas, Bolakhrif, Najoua, Kaiser, Jesko, Nagel-Steger, Luitgard, Gremer, Lothar, Gohlke, Holger, Willbold, Dieter
Publicado 2022

Human myocytes are protected from titin aggregation-induced stiffening by small heat shock proteins

por Kötter, Sebastian, Unger, Andreas, Hamdani, Nazha, Lang, Patrick, Vorgerd, Matthias, Nagel-Steger, Luitgard, Linke, Wolfgang A.
Publicado 2014

Molecular Interactions between Prions as Seeds and Recombinant Prion Proteins as Substrates Resemble the Biological Interspecies Barrier In Vitro

por Panza, Giannantonio, Luers, Lars, Stöhr, Jan, Nagel-Steger, Luitgard, Weiβ, Jürgen, Riesner, Detlev, Willbold, Dieter, Birkmann, Eva
Publicado 2010

Seeded Fibrillation as Molecular Basis of the Species Barrier in Human Prion Diseases

por Luers, Lars, Bannach, Oliver, Stöhr, Jan, Wördehoff, Michael Marius, Wolff, Martin, Nagel-Steger, Luitgard, Riesner, Detlev, Willbold, Dieter, Birkmann, Eva
Publicado 2013

Aβ42 pentamers/hexamers are the smallest detectable oligomers in solution

por Wolff, Martin, Zhang-Haagen, Bo, Decker, Christina, Barz, Bogdan, Schneider, Mario, Biehl, Ralf, Radulescu, Aurel, Strodel, Birgit, Willbold, Dieter, Nagel-Steger, Luitgard
Publicado 2017

EDTA aggregates induce SYPRO orange-based fluorescence in thermal shift assay

por Kroeger, Tobias, Frieg, Benedikt, Zhang, Tao, Hansen, Finn K., Marmann, Andreas, Proksch, Peter, Nagel-Steger, Luitgard, Groth, Georg, Smits, Sander H. J., Gohlke, Holger
Publicado 2017

Double-strand DNA end-binding and sliding of the toroidal CRISPR-associated protein Csn2

por Arslan, Zihni, Wurm, Reinhild, Brener, Oleksandr, Ellinger, Philipp, Nagel-Steger, Luitgard, Oesterhelt, Filipp, Schmitt, Lutz, Willbold, Dieter, Wagner, Rolf, Gohlke, Holger, Smits, Sander H. J., Pul, Ümit
Publicado 2013

The Aβ oligomer eliminating D-enantiomeric peptide RD2 improves cognition without changing plaque pathology

por van Groen, Thomas, Schemmert, Sarah, Brener, Oleksandr, Gremer, Lothar, Ziehm, Tamar, Tusche, Markus, Nagel-Steger, Luitgard, Kadish, Inga, Schartmann, Elena, Elfgen, Anne, Jürgens, Dagmar, Willuweit, Antje, Kutzsche, Janine, Willbold, Dieter
Publicado 2017

Structure of the SLy1 SAM homodimer reveals a new interface for SAM domain self-association

por Kukuk, Laura, Dingley, Andrew J., Granzin, Joachim, Nagel-Steger, Luitgard, Thiagarajan-Rosenkranz, Pallavi, Ciupka, Daniel, Hänel, Karen, Batra-Safferling, Renu, Pacheco, Victor, Stoldt, Matthias, Pfeffer, Klaus, Beer-Hammer, Sandra, Willbold, Dieter, Koenig, Bernd W.
Publicado 2019

Biophysical Characterization of Nucleophosmin Interactions with Human Immunodeficiency Virus Rev and Herpes Simplex Virus US11

por Nouri, Kazem, Moll, Jens M., Milroy, Lech-Gustav, Hain, Anika, Dvorsky, Radovan, Amin, Ehsan, Lenders, Michael, Nagel-Steger, Luitgard, Howe, Sebastian, Smits, Sander H. J., Hengel, Hartmut, Schmitt, Lutz, Münk, Carsten, Brunsveld, Luc, Ahmadian, Mohammad R.
Publicado 2015

Biophysical and pharmacokinetic characterization of a small-molecule inhibitor of RUNX1/ETO tetramerization with anti-leukemic effects

por Gopalswamy, Mohanraj, Kroeger, Tobias, Bickel, David, Frieg, Benedikt, Akter, Shahina, Schott-Verdugo, Stephan, Viegas, Aldino, Pauly, Thomas, Mayer, Manuela, Przibilla, Julia, Reiners, Jens, Nagel-Steger, Luitgard, Smits, Sander H. J., Groth, Georg, Etzkorn, Manuel, Gohlke, Holger
Publicado 2022

An essential role of the autophagy activating kinase ULK1 in snRNP biogenesis

por Schmitz, Katharina, Cox, Jan, Esser, Lea Marie, Voss, Martin, Sander, Katja, Löffler, Antje, Hillebrand, Frank, Erkelenz, Steffen, Schaal, Heiner, Kähne, Thilo, Klinker, Stefan, Zhang, Tao, Nagel-Steger, Luitgard, Willbold, Dieter, Seggewiß, Sabine, Schlütermann, David, Stork, Björn, Grimmler, Matthias, Wesselborg, Sebastian, Peter, Christoph
Publicado 2021

Widespread amyloidogenicity potential of multiple myeloma patient-derived immunoglobulin light chains

por Sternke-Hoffmann, Rebecca, Pauly, Thomas, Norrild, Rasmus K., Hansen, Jan, Tucholski, Florian, Høie, Magnus Haraldson, Marcatili, Paolo, Dupré, Mathieu, Duchateau, Magalie, Rey, Martial, Malosse, Christian, Metzger, Sabine, Boquoi, Amelie, Platten, Florian, Egelhaaf, Stefan U., Chamot-Rooke, Julia, Fenk, Roland, Nagel-Steger, Luitgard, Haas, Rainer, Buell, Alexander K.
Publicado 2023

QIAD assay for quantitating a compound’s efficacy in elimination of toxic Aβ oligomers

por Brener, Oleksandr, Dunkelmann, Tina, Gremer, Lothar, van Groen, Thomas, Mirecka, Ewa A., Kadish, Inga, Willuweit, Antje, Kutzsche, Janine, Jürgens, Dagmar, Rudolph, Stephan, Tusche, Markus, Bongen, Patrick, Pietruszka, Jörg, Oesterhelt, Filipp, Langen, Karl-Josef, Demuth, Hans-Ulrich, Janssen, Arnold, Hoyer, Wolfgang, Funke, Susanne A., Nagel-Steger, Luitgard, Willbold, Dieter
Publicado 2015

A Multilaboratory Comparison of Calibration Accuracy and the Performance of External References in Analytical Ultracentrifugation

por Zhao, Huaying, Ghirlando, Rodolfo, Alfonso, Carlos, Arisaka, Fumio, Attali, Ilan, Bain, David L., Bakhtina, Marina M., Becker, Donald F., Bedwell, Gregory J., Bekdemir, Ahmet, Besong, Tabot M. D., Birck, Catherine, Brautigam, Chad A., Brennerman, William, Byron, Olwyn, Bzowska, Agnieszka, Chaires, Jonathan B., Chaton, Catherine T., Cölfen, Helmut, Connaghan, Keith D., Crowley, Kimberly A., Curth, Ute, Daviter, Tina, Dean, William L., Díez, Ana I., Ebel, Christine, Eckert, Debra M., Eisele, Leslie E., Eisenstein, Edward, England, Patrick, Escalante, Carlos, Fagan, Jeffrey A., Fairman, Robert, Finn, Ron M., Fischle, Wolfgang, de la Torre, José García, Gor, Jayesh, Gustafsson, Henning, Hall, Damien, Harding, Stephen E., Cifre, José G. Hernández, Herr, Andrew B., Howell, Elizabeth E., Isaac, Richard S., Jao, Shu-Chuan, Jose, Davis, Kim, Soon-Jong, Kokona, Bashkim, Kornblatt, Jack A., Kosek, Dalibor, Krayukhina, Elena, Krzizike, Daniel, Kusznir, Eric A., Kwon, Hyewon, Larson, Adam, Laue, Thomas M., Le Roy, Aline, Leech, Andrew P., Lilie, Hauke, Luger, Karolin, Luque-Ortega, Juan R., Ma, Jia, May, Carrie A., Maynard, Ernest L., Modrak-Wojcik, Anna, Mok, Yee-Foong, Mücke, Norbert, Nagel-Steger, Luitgard, Narlikar, Geeta J., Noda, Masanori, Nourse, Amanda, Obsil, Tomas, Park, Chad K., Park, Jin-Ku, Pawelek, Peter D., Perdue, Erby E., Perkins, Stephen J., Perugini, Matthew A., Peterson, Craig L., Peverelli, Martin G., Piszczek, Grzegorz, Prag, Gali, Prevelige, Peter E., Raynal, Bertrand D. E., Rezabkova, Lenka, Richter, Klaus, Ringel, Alison E., Rosenberg, Rose, Rowe, Arthur J., Rufer, Arne C., Scott, David J., Seravalli, Javier G., Solovyova, Alexandra S., Song, Renjie, Staunton, David, Stoddard, Caitlin, Stott, Katherine, Strauss, Holger M., Streicher, Werner W., Sumida, John P., Swygert, Sarah G., Szczepanowski, Roman H., Tessmer, Ingrid, Toth, Ronald T., Tripathy, Ashutosh, Uchiyama, Susumu, Uebel, Stephan F. W., Unzai, Satoru, Gruber, Anna Vitlin, von Hippel, Peter H., Wandrey, Christine, Wang, Szu-Huan, Weitzel, Steven E., Wielgus-Kutrowska, Beata, Wolberger, Cynthia, Wolff, Martin, Wright, Edward, Wu, Yu-Sung, Wubben, Jacinta M., Schuck, Peter
Publicado 2015