The Act1 D10N Missense Variant Impairs CD40 Signaling in Human B-Cells

por Yu, Ning, Lambert, Sylviane, Bornstein, Joshua, Nair, Rajan P., Enerbäck, Charlotta, Elder, James T.
Publicado 2018

Quantifying Differences in Heritability among Psoriatic Arthritis (PsA), Cutaneous Psoriasis (PsC) and Psoriasis vulgaris (PsV)

por Li, Quan, Chandran, Vinod, Tsoi, Lam, O’Rielly, Darren, Nair, Rajan P., Gladman, Dafna, Elder, James T., Rahman, Proton
Publicado 2020

TNFAIP3 Gene Polymorphisms Are Associated with Response to TNF Blockade in Psoriasis

por Tejasvi, Trilokraj, Stuart, Philip E., Chandran, Vinod, Voorhees, John J., Gladman, Dafna D., Rahman, Proton, Elder, James T., Nair, Rajan P.
Publicado 2011

Association of β-defensin copy number and psoriasis in three cohorts of European origin

por Stuart, Philip E, Hüffmeier, Ulrike, Nair, Rajan P, Palla, Raquel, Tejasvi, Trilokraj, Schalkwijk, Joost, Elder, James T, Reis, Andre, Armour, John AL
Publicado 2012

Heterogeneity of Inflammatory and Cytokine Networks in Chronic Plaque Psoriasis

por Swindell, William R., Xing, Xianying, Stuart, Philip E., Chen, Cynthia S., Aphale, Abhishek, Nair, Rajan P., Voorhees, John J., Elder, James T., Johnston, Andrew, Gudjonsson, Johann E.
Publicado 2012

Serum bone-turnover biomarkers are associated with the occurrence of peripheral and axial arthritis in psoriatic disease: a prospective cross-sectional comparative study

por Jadon, Deepak R., Sengupta, Raj, Nightingale, Alison, Lu, Hui, Dunphy, Juliet, Green, Amelia, Elder, James T., Nair, Rajan P., Korendowych, Eleanor, Lindsay, Mark A., McHugh, Neil J.
Publicado 2017

A Single SNP Surrogate for Genotyping HLA-C*06:02 in Diverse Populations

por Stuart, Philip E., Tejasvi, Trilokraj, Shaiq, Pakeeza A., Kullavanijaya, Preya, Qamar, Raheel, Raja, Ghazala K., Li, Yanming, Voorhees, John J., Abecasis, Goncalo R., Elder, James T., Nair, Rajan P.
Publicado 2014

Proteogenomic analysis of psoriasis reveals discordant and concordant changes in mRNA and protein abundance

por Swindell, William R., Remmer, Henriette A., Sarkar, Mrinal K., Xing, Xianying, Barnes, Drew H., Wolterink, Liza, Voorhees, John J., Nair, Rajan P., Johnston, Andrew, Elder, James T., Gudjonsson, Johann E.
Publicado 2015

Integrative Approach to Reveal Cell Type Specificity and Gene Candidates for Psoriatic Arthritis Outside the MHC

por Patrick, Matthew T., Stuart, Philip E., Raja, Kalpana, Chi, Sunyi, He, Zhi, Voorhees, John J., Tejasvi, Trilokraj, Gudjonsson, Johann E., Kahlenberg, J. Michelle, Chandran, Vinod, Rahman, Proton, Gladman, Dafna D., Nair, Rajan P., Elder, James T., Tsoi, Lam C.
Publicado 2019

Transcriptome analysis of psoriasis in a large case-control sample: RNA-seq provides insights into disease mechanisms

por Li, Bingshan, Tsoi, Lam C., Swindell, William R., Gudjonsson, Johann E., Tejasvi, Trilokraj, Johnston, Andrew, Ding, Jun, Stuart, Philip E., Xing, Xianying, Kochkodan, James J., Voorhees, John J., Kang, Hyun M., Nair, Rajan P., Abecasis, Goncalo R., Elder, James T.
Publicado 2014

VGLL3-regulated gene network as a promoter of sex biased autoimmune diseases

por Liang, Yun, Tsoi, Lam C, Xing, Xianying, Beamer, Maria A, Swindell, William R, Sarkar, Mrinal K, Berthier, Celine C, Stuart, Philip E, Harms, Paul W., Nair, Rajan P., Elder, James T., Voorhees, John J., Kahlenberg, J. Michelle, Gudjonsson, Johann E.
Publicado 2016

Multiple Loci within the Major Histocompatibility Complex Confer Risk of Psoriasis

por Feng, Bing-Jian, Sun, Liang-Dan, Soltani-Arabshahi, Razieh, Bowcock, Anne M., Nair, Rajan P., Stuart, Philip, Elder, James T., Schrodi, Steven J., Begovich, Ann B., Abecasis, Gonçalo R., Zhang, Xue-Jun, Callis-Duffin, Kristina P., Krueger, Gerald G., Goldgar, David E.
Publicado 2009

Analysis of long non-coding RNAs highlights tissue-specific expression patterns and epigenetic profiles in normal and psoriatic skin

por Tsoi, Lam C, Iyer, Matthew K, Stuart, Philip E, Swindell, William R, Gudjonsson, Johann E, Tejasvi, Trilokraj, Sarkar, Mrinal K, Li, Bingshan, Ding, Jun, Voorhees, John J, Kang, Hyun M, Nair, Rajan P, Chinnaiyan, Arul M, Abecasis, Goncalo R, Elder, James T
Publicado 2015

Genome-Wide Expression Profiling of Five Mouse Models Identifies Similarities and Differences with Human Psoriasis

por Swindell, William R., Johnston, Andrew, Carbajal, Steve, Han, Gangwen, Wohn, Christian, Lu, Jun, Xing, Xianying, Nair, Rajan P., Voorhees, John J., Elder, James T., Wang, Xiao-Jing, Sano, Shigetoshi, Prens, Errol P., DiGiovanni, John, Pittelkow, Mark R., Ward, Nicole L., Gudjonsson, Johann E.
Publicado 2011

Large-Scale Imputation of KIR Copy Number and HLA Alleles in North American and European Psoriasis Case-Control Cohorts Reveals Association of Inhibitory KIR2DL2 With Psoriasis

por Ahn, Richard, Vukcevic, Damjan, Motyer, Allan, Nititham, Joanne, Squire, David McG., Hollenbach, Jill A., Norman, Paul J., Ellinghaus, Eva, Nair, Rajan P., Tsoi, Lam C., Oksenberg, Jorge, Foerster, John, Lieb, Wolfgang, Weidinger, Stephan, Franke, Andre, Elder, James T., Jorgenson, Eric, Leslie, Stephen, Liao, Wilson
Publicado 2021

IFN-γ and TNF-α synergism may provide a link between psoriasis and inflammatory atherogenesis

por Mehta, Nehal N., Teague, Heather L., Swindell, William R., Baumer, Yvonne, Ward, Nicole L., Xing, Xianying, Baugous, Brooke, Johnston, Andrew, Joshi, Aditya A., Silverman, Joanna, Barnes, Drew H., Wolterink, Liza, Nair, Rajan P., Stuart, Philip E., Playford, Martin, Voorhees, John J., Sarkar, Mrinal K., Elder, James T., Gallagher, Katherine, Ganesh, Santhi K., Gudjonsson, Johann E.
Publicado 2017

Transethnic analysis of psoriasis susceptibility in South Asians and Europeans enhances fine mapping in the MHC and genome wide

por Stuart, Philip E., Tsoi, Lam C., Nair, Rajan P., Ghosh, Manju, Kabra, Madhulika, Shaiq, Pakeeza A., Raja, Ghazala K., Qamar, Raheel, Thelma, B.K., Patrick, Matthew T., Parihar, Anita, Singh, Sonam, Khandpur, Sujay, Kumar, Uma, Wittig, Michael, Degenhardt, Frauke, Tejasvi, Trilokraj, Voorhees, John J., Weidinger, Stephan, Franke, Andre, Abecasis, Goncalo R., Sharma, Vinod K., Elder, James T.
Publicado 2021

Genome-wide association analysis identifies three psoriasis susceptibility loci

por Stuart, Philip E., Nair, Rajan P., Ellinghaus, Eva, Ding, Jun, Tejasvi, Trilokraj, Gudjonsson, Johann E., Li, Yun, Weidinger, Stephan, Eberlein, Bernadette, Gieger, Christian, Wichmann, H. Erich, Kunz, Manfred, Ike, Robert, Krueger, Gerald G., Bowcock, Anne M., Mroweitz, Ulrich, Lim, Henry W., Voorhees, John J., Abecasis, Goncalo R., Weichenthal, Michael, Franke, Andre, Rahman, Proton, Gladman, Dafna D., Elder, James T.
Publicado 2010

Fine Mapping Major Histocompatibility Complex Associations in Psoriasis and Its Clinical Subtypes

por Okada, Yukinori, Han, Buhm, Tsoi, Lam C., Stuart, Philip E., Ellinghaus, Eva, Tejasvi, Trilokraj, Chandran, Vinod, Pellett, Fawnda, Pollock, Remy, Bowcock, Anne M., Krueger, Gerald G., Weichenthal, Michael, Voorhees, John J., Rahman, Proton, Gregersen, Peter K., Franke, Andre, Nair, Rajan P., Abecasis, Gonçalo R., Gladman, Dafna D., Elder, James T., de Bakker, Paul I.W., Raychaudhuri, Soumya
Publicado 2014

Genome-wide meta-analysis of Psoriatic Arthritis Identifies Susceptibility Locus at REL

por Ellinghaus, Eva, Stuart, Philip E., Ellinghaus, David, Nair, Rajan P., Debrus, Sophie, Raelson, John V., Belouchi, Majid, Tejasvi, Trilokraj, Li, Yanming, Tsoi, Lam C., Onken, Anna T., Esko, Tonu, Metspalu, Andres, Rahman, Proton, Gladman, Dafna D., Bowcock, Anne M., Helms, Cynthia, Krueger, Gerald G., Koks, Sulev, Kingo, Külli, Gieger, Christian, Wichmann, H. Erich, Mrowietz, Ulrich, Weidinger, Stephan, Schreiber, Stefan, Abecasis, Gonçalo R., Elder, James T., Weichenthal, Michael, Franke, Andre
Publicado 2011