Update on Advances in Research on Idiosyncratic Drug-Induced Liver Injury

por Kim, Seung-Hyun, Naisbitt, Dean J.
Publicado 2016

Why drug exposure is frequently associated with T-cell mediated cutaneous hypersensitivity reactions

por Line, James, Saville, Eleanor, Meng, Xiaoli, Naisbitt, Dean
Publicado 2023

In-Vitro Approaches to Predict and Study T-Cell Mediated Hypersensitivity to Drugs

por Hammond, Sean, Thomson, Paul, Meng, Xiaoli, Naisbitt, Dean
Publicado 2021

Does immune checkpoint inhibitor therapy increase the frequency of adverse reactions to concomitant medications?

por Hammond, Sean, Olsson‐Brown, Anna, Grice, Sophie, Naisbitt, Dean J.
Publicado 2022

Dapsone hypersensitivity syndrome

por Zhao, Qing, Sun, Lele, Sun, Yonghu, Naisbitt, Dean, Liu, Hong, Zhang, Furen
Publicado 2023

Characterization of Teicoplanin-Specific T-Cells from Drug Naïve Donors Expressing HLA-A*32:01

por Gardner, Joshua, Ogese, Monday, Betts, Catherine J., Pirmohamed, Munir, Naisbitt, Dean J.
Publicado 2022

Characterization of primary human T-cell responses to p-phenylenediamine and Bandrowski's base

por Gibson, Andrew, Seung-Hyun, Kim, Faulkner, Lee, Park, B Kevin, Naisbitt, Dean J
Publicado 2014

Tolvaptan- and Tolvaptan-Metabolite-Responsive T Cells in Patients with Drug-Induced Liver Injury

por Gibson, Andrew, Hammond, Sean, Jaruthamsophon, Kanoot, Roth, Sharin, Mosedale, Merrie, Naisbitt, Dean J.
Publicado 2020

Detection of interleukin-22 secreting T-cells in piperacillin hypersensitive patients with cystic fibrosis

por Sullivan, Andrew, Wang, Eryi, Farrell, John, Whitaker, Paul, Peckham, Daniel, Park, B Kevin, Naisbitt, Dean
Publicado 2014

Establishment of an HLA-typed cohort of 1000 healthy blood donors and use of a dendritic cell priming assay to prime naive T cells to structurally divergent drugs

por Faulkner, Lee, Wood, Sally, Van Eker, Diane, Alfirevic, Ana, Pirmohamed, Munir, Naisbitt, Dean, Park, Kevin
Publicado 2014

Characterization of the TCR V repertoire of piperacillin-specific T-cells

por Al-Attar, Zaid, Faulkner, Lee, Farrell, John, Whitaker, Paul, Peckham, Daniel, Park, Kevin, Naisbitt, Dean
Publicado 2014

Skewing of the TCR V repertoire in SMX-NO specific T cell responses

por Faulkner, Lee, Lichtenfels, Maike, Esser, Philipp, Martin, Stefan, Alfirevic, Ana, Pirmohamed, Munir, Naisbitt, Dean, Park, Kevin
Publicado 2014

Isoniazid-specific T-cell Responses in patients with anti-tuberculosis drug related liver injury

por Usui, Toru, Saide, Katy, Meng, Xiaoli, Whitaker, Paul, Peckham, Daniel, French, Neil, Naisbitt, Dean, Park, Kevin
Publicado 2014

Chemical modification of the 6'-amino cyclopropyl of abacavir eliminates HLA-B*57:01-restricted CD8+ T-cell activation without loss of antiviral activity

por Alhaidari, Mohammad, Yang, Emma, Berry, Neil, Owen, Andrew, Clarke, Steve, O'Neill, Paul, Naisbitt, Dean, Park, Kevin
Publicado 2014

Characterization of amoxicillin and clavulanic-acid-responsive CD4+ And CD8+ T-cells in patients with co-amoxiclav-induced liver injury

por Kim, Seung-Hyun, Saide, Katy, Yuan, Ye, Daly, Ann, Alfirevic, Ana, Pirmohamed, Munir, Park, Kevin, Naisbitt, Dean
Publicado 2014

Identification of susceptible HLA class II co-amoxiclav genotypes based on the analysis of drug-specific T-cells from patients with liver injury

por Saide, Katy, Kim, Seung-Hyun, Yuan, Ye, Daly, Ann, Alfirevic, Ana, Pirmohamed, Munir, Park, Kevin, Naisbitt, Dean
Publicado 2014

Characterization of Drug-Specific CD4(+) T-Cells Reveals Possible Roles of HLA Class II in the Pathogenesis of Carbamazepine Hypersensitivity Reactions

por Jaruthamsophon, Kanoot, Thomson, Paul J., Hammond, Sean, Zhang, Eunice, Alfirevic, Ana, Sukasem, Chonlaphat, Naisbitt, Dean J., Pirmohamed, Munir
Publicado 2023

HLA-DQ restricted activation of nitroso-sulfamethoxazole-specific CD4+ T-lymphocytes

por Ogese, Monday, Saide, Katy, Whitaker, Paul, Peckham, Daniel, Faulkner, Lee, Alfirevic, Ana, Pirmohamed, Munir, Park, Kevin, Naisbitt, Dean
Publicado 2014

Abacavir forms novel cross-linking abacavir protein adducts in patients

por Meng, Xiaoli, Lawrenson, Alexandre, Berry, Neil, Maggs, James, French, Neil, Back, David, Khoo, Saye, Naisbitt, Dean, Park, Kevin
Publicado 2014

Deciphering Adverse Drug Reactions: In Vitro Priming and Characterization of Vancomycin-Specific T Cells From Healthy Donors Expressing HLA-A*32:01

por Ogese, Monday O, Lister, Adam, Gardner, Joshua, Meng, Xiaoli, Alfirevic, Ana, Pirmohamed, Munir, Park, B Kevin, Naisbitt, Dean J
Publicado 2021