CrossCheck: an open-source web tool for high-throughput screen data analysis

por Najafov, Jamil, Najafov, Ayaz
Publicado 2017

Necroptosis in development and diseases

por Shan, Bing, Pan, Heling, Najafov, Ayaz, Yuan, Junying
Publicado 2018

Synergistic effect of a novel autophagy inhibitor and Quizartinib enhances cancer cell death

por Ouchida, Amanda Tomie, Li, Yingbo, Geng, Jiefei, Najafov, Ayaz, Ofengeim, Dimitry, Sun, Xiaoxiao, Yu, Qiang, Yuan, Junying
Publicado 2018

The UNC-45 chaperone mediates sarcomere assembly through myosin degradation in Caenorhabditis elegans

por Landsverk, Megan L., Li, Shumin, Hutagalung, Alex H., Najafov, Ayaz, Hoppe, Thorsten, Barral, José M., Epstein, Henry F.
Publicado 2007

MENA Is a Transcriptional Target of the Wnt/Beta-Catenin Pathway

por Najafov, Ayaz, Şeker, Tuncay, Even, İpek, Hoxhaj, Gerta, Selvi, Osman, Özel, Duygu Esen, Koman, Ahmet, Birgül-İyison, Necla
Publicado 2012

Pharmacological targeting of MCL-1 promotes mitophagy and improves disease pathologies in an Alzheimer’s disease mouse model

por Cen, Xufeng, Chen, Yanying, Xu, Xiaoyan, Wu, Ronghai, He, Fusheng, Zhao, Qingwei, Sun, Qiming, Yi, Cong, Wu, Jie, Najafov, Ayaz, Xia, Hongguang
Publicado 2020

Casein kinase-1γ1 and 3 stimulate tumor necrosis factor-induced necroptosis through RIPK3

por Lee, Song-Yi, Kim, Hyunjoo, Li, Cathena Meiling, Kang, Jaemin, Najafov, Ayaz, Jung, Muhah, Kang, Soosung, Wang, Shaomeng, Yuan, Junying, Jung, Yong-Keun
Publicado 2019

The E3 ubiquitin ligase ZNRF2 is a substrate of mTORC1 and regulates its activation by amino acids

por Hoxhaj, Gerta, Caddye, Edward, Najafov, Ayaz, Houde, Vanessa P, Johnson, Catherine, Dissanayake, Kumara, Toth, Rachel, Campbell, David G, Prescott, Alan R, MacKintosh, Carol
Publicado 2016

ABIN-1 Regulates RIPK1 Activation by Bridging M1 ubiquitination with K63 Deubiquitination in TNF-RSC

por Dziedzic, Slawomir A., Su, Zhenyi, Barrett, Vica Jean, Najafov, Ayaz, Mookhitiar, Adnan K., Amin, Palak, Pan, Heling, Sun, Li, Zhu, Hong, Ma, Averil, Abbott, Derek W., Yuan, Junying
Publicado 2017

PDK1 regulates VDJ recombination, cell-cycle exit and survival during B-cell development

por Venigalla, Ram K C, McGuire, Victoria A, Clarke, Rosemary, Patterson-Kane, Janet C, Najafov, Ayaz, Toth, Rachel, McCarthy, Pierre C, Simeons, Frederick, Stojanovski, Laste, Arthur, J Simon C
Publicado 2013

Regulation of RIPK1 activation by TAK1-mediated phosphorylation dictates apoptosis and necroptosis

por Geng, Jiefei, Ito, Yasushi, Shi, Linyu, Amin, Palak, Chu, Jiachen, Ouchida, Amanda Tomie, Mookhtiar, Adnan Kasim, Zhao, Heng, Xu, Daichao, Shan, Bing, Najafov, Ayaz, Gao, Guangping, Akira, Shizuo, Yuan, Junying
Publicado 2017

BRAF and AXL oncogenes drive RIPK3 expression loss in cancer

por Najafov, Ayaz, Zervantonakis, Ioannis K., Mookhtiar, Adnan K., Greninger, Patricia, March, Ryan J., Egan, Regina K., Luu, Hoang Son, Stover, Daniel G., Matulonis, Ursula A., Benes, Cyril H., Yuan, Junying
Publicado 2018

NEK1-mediated retromer trafficking promotes blood–brain barrier integrity by regulating glucose metabolism and RIPK1 activation

por Wang, Huibing, Qi, Weiwei, Zou, Chengyu, Xie, Zhangdan, Zhang, Mengmeng, Naito, Masanori Gomi, Mifflin, Lauren, Liu, Zhen, Najafov, Ayaz, Pan, Heling, Shan, Bing, Li, Ying, Zhu, Zheng-Jiang, Yuan, Junying
Publicado 2021

Metformin activates chaperone-mediated autophagy and improves disease pathologies in an Alzheimer disease mouse model

por Xu, Xiaoyan, Sun, Yaqin, Cen, Xufeng, Shan, Bing, Zhao, Qingwei, Xie, Tingxue, Wang, Zhe, Hou, Tingjun, Xue, Yu, Zhang, Mengmeng, Peng, Di, Sun, Qiming, Yi, Cong, Najafov, Ayaz, Xia, Hongguang
Publicado 2021

Correction to: Metformin activates chaperone-mediated autophagy and improves disease pathologies in an Alzheimer disease mouse model

por Xu, Xiaoyan, Sun, Yaqin, Cen, Xufeng, Shan, Bing, Zhao, Qingwei, Xie, Tingxue, Wang, Zhe, Hou, Tingjun, Xue, Yu, Zhang, Mengmeng, Peng, Di, Sun, Qiming, Yi, Cong, Najafov, Ayaz, Xia, Hongguang
Publicado 2021

Degradation of HK2 by chaperone-mediated autophagy promotes metabolic catastrophe and cell death

por Xia, Hong-guang, Najafov, Ayaz, Geng, Jiefei, Galan-Acosta, Lorena, Han, Xuemei, Guo, Yuan, Shan, Bing, Zhang, Yaoyang, Norberg, Erik, Zhang, Tao, Pan, Lifeng, Liu, Junli, Coloff, Jonathan L., Ofengeim, Dimitry, Zhu, Hong, Wu, Kejia, Cai, Yu, Yates, John R., Zhu, Zhengjiang, Yuan, Junying, Vakifahmetoglu-Norberg, Helin
Publicado 2015

Correction: Degradation of HK2 by chaperone-mediated autophagy promotes metabolic catastrophe and cell death

por Xia, Hong-guang, Najafov, Ayaz, Geng, Jiefei, Galan-Acosta, Lorena, Han, Xuemei, Guo, Yuan, Shan, Bing, Zhang, Yaoyang, Norberg, Erik, Zhang, Tao, Pan, Lifeng, Liu, Junli, Coloff, Jonathan L., Ofengeim, Dimitry, Zhu, Hong, Wu, Kejia, Cai, Yu, Yates, John R., Zhu, Zhengjiang, Yuan, Junying, Vakifahmetoglu-Norberg, Helin
Publicado 2016

ARIH1 signaling promotes anti-tumor immunity by targeting PD-L1 for proteasomal degradation

por Wu, Youqian, Zhang, Chao, Liu, Xiaolan, He, Zhengfu, Shan, Bing, Zeng, Qingxin, Zhao, Qingwei, Zhu, Huaying, Liao, Hongwei, Cen, Xufeng, Xu, Xiaoyan, Zhang, Mengmeng, Hou, Tingjun, Wang, Zhe, Yan, Huanhuan, Yang, Shuying, Sun, Yaqin, Chen, Yanying, Wu, Ronghai, Xie, Tingxue, Chen, Wei, Najafov, Ayaz, Ying, Songmin, Xia, Hongguang
Publicado 2021

G-protein-coupled receptors regulate autophagy by ZBTB16-mediated ubiquitination and proteasomal degradation of Atg14L

por Zhang, Tao, Dong, Kangyun, Liang, Wei, Xu, Daichao, Xia, Hongguang, Geng, Jiefei, Najafov, Ayaz, Liu, Min, Li, Yanxia, Han, Xiaoran, Xiao, Juan, Jin, Zhenzhen, Peng, Ting, Gao, Yang, Cai, Yu, Qi, Chunting, Zhang, Qing, Sun, Anyang, Lipinski, Marta, Zhu, Hong, Xiong, Yue, Pandolfi, Pier Paolo, Li, He, Yu, Qiang, Yuan, Junying
Publicado 2015