Opposing roles of RNF8/RNF168 and deubiquitinating enzymes in ubiquitination-dependent DNA double-strand break response signaling and DNA-repair pathway choice

por Nakada, Shinichiro
Publicado 2016

PP4 is a γH2AX phosphatase required for recovery from the DNA damage checkpoint

por Nakada, Shinichiro, Chen, Ginny I, Gingras, Anne-Claude, Durocher, Daniel
Publicado 2008

Precise and efficient nucleotide substitution near genomic nick via noncanonical homology-directed repair

por Nakajima, Kazuhiro, Zhou, Yue, Tomita, Akiko, Hirade, Yoshihiro, Gurumurthy, Channabasavaiah B., Nakada, Shinichiro
Publicado 2018

Inducing multiple nicks promotes interhomolog homologous recombination to correct heterozygous mutations in somatic cells

por Tomita, Akiko, Sasanuma, Hiroyuki, Owa, Tomoo, Nakazawa, Yuka, Shimada, Mayuko, Fukuoka, Takahiro, Ogi, Tomoo, Nakada, Shinichiro
Publicado 2023

Structural insights into two distinct binding modules for Lys63-linked polyubiquitin chains in RNF168

por Takahashi, Tomio S., Hirade, Yoshihiro, Toma, Aya, Sato, Yusuke, Yamagata, Atsushi, Goto-Ito, Sakurako, Tomita, Akiko, Nakada, Shinichiro, Fukai, Shuya
Publicado 2018

Structural Basis for Ubiquitin Recognition by Ubiquitin-Binding Zinc Finger of FAAP20

por Toma, Aya, Takahashi, Tomio S., Sato, Yusuke, Yamagata, Atsushi, Goto-Ito, Sakurako, Nakada, Shinichiro, Fukuto, Atsuhiko, Horikoshi, Yasunori, Tashiro, Satoshi, Fukai, Shuya
Publicado 2015

The Outcome of Conversion to Hand-Assisted Laparoscopic Surgery in Laparoscopic Liver Resection

por Nakada, Shinichiro, Otsuka, Yuichiro, Ishii, Jun, Maeda, Tetsuya, Kimura, Kazutaka, Matsumoto, Yu, Ito, Yuko, Shimada, Hideaki, Funahashi, Kimihiko, Ohtsuka, Masayuki, Kaneko, Hironori
Publicado 2023

UBC13-Mediated Ubiquitin Signaling Promotes Removal of Blocking Adducts from DNA Double-Strand Breaks

por Akagawa, Remi, Trinh, Hai Thanh, Saha, Liton Kumar, Tsuda, Masataka, Hirota, Kouji, Yamada, Shintaro, Shibata, Atsushi, Kanemaki, Masato T., Nakada, Shinichiro, Takeda, Shunichi, Sasanuma, Hiroyuki
Publicado 2020

A Screen for Suppressors of Gross Chromosomal Rearrangements Identifies a Conserved Role for PLP in Preventing DNA Lesions

por Kanellis, Pamela, Gagliardi, Mark, Banath, Judit P, Szilard, Rachel K, Nakada, Shinichiro, Galicia, Sarah, Sweeney, Frederic D, Cabelof, Diane C, Olive, Peggy L, Durocher, Daniel
Publicado 2007

T315I mutation of BCR-ABL1 into human Philadelphia chromosome-positive leukemia cell lines by homologous recombination using the CRISPR/Cas9 system

por Tamai, Minori, Inukai, Takeshi, Kojika, Satoru, Abe, Masako, Kagami, Keiko, Harama, Daisuke, Shinohara, Tamao, Watanabe, Atsushi, Oshiro, Hiroko, Akahane, Koshi, Goi, Kumiko, Sugihara, Eiji, Nakada, Shinichiro, Sugita, Kanji
Publicado 2018

CRISPR-Cas3 induces broad and unidirectional genome editing in human cells

por Morisaka, Hiroyuki, Yoshimi, Kazuto, Okuzaki, Yuya, Gee, Peter, Kunihiro, Yayoi, Sonpho, Ekasit, Xu, Huaigeng, Sasakawa, Noriko, Naito, Yuki, Nakada, Shinichiro, Yamamoto, Takashi, Sano, Shigetoshi, Hotta, Akitsu, Takeda, Junji, Mashimo, Tomoji
Publicado 2019