Using a Minimal Parameter Set for Early Diagnosis of Hemophagocytic Lymphohistiocytosis in Non-European Children

por Nakashima, Yu, Koga, Hiroshi
Publicado 2022

Synthesis of 2-oxoglutarate derivatives and their evaluation as cosubstrates and inhibitors of human aspartate/asparagine-β-hydroxylase

por Brewitz, Lennart, Nakashima, Yu, Schofield, Christopher J.
Publicado 2020

Metagenomic Analysis of the Sponge Discodermia Reveals the Production of the Cyanobacterial Natural Product Kasumigamide by ‘Entotheonella’

por Nakashima, Yu, Egami, Yoko, Kimura, Miki, Wakimoto, Toshiyuki, Abe, Ikuro
Publicado 2016

Fluorinated derivatives of pyridine-2,4-dicarboxylate are potent inhibitors of human 2-oxoglutarate dependent oxygenases

por Brewitz, Lennart, Nakashima, Yu, Tumber, Anthony, Salah, Eidarus, Schofield, Christopher J.
Publicado 2021

2-Oxoglutarate derivatives can selectively enhance or inhibit the activity of human oxygenases

por Nakashima, Yu, Brewitz, Lennart, Tumber, Anthony, Salah, Eidarus, Schofield, Christopher J.
Publicado 2021

Structure of lasso peptide epimerase MslH reveals metal-dependent acid/base catalytic mechanism

por Nakashima, Yu, Kawakami, Atsushi, Ogasawara, Yasushi, Maeki, Masatoshi, Tokeshi, Manabu, Dairi, Tohru, Morita, Hiroyuki
Publicado 2023

Structure function and engineering of multifunctional non-heme iron dependent oxygenases in fungal meroterpenoid biosynthesis

por Nakashima, Yu, Mori, Takahiro, Nakamura, Hitomi, Awakawa, Takayoshi, Hoshino, Shotaro, Senda, Miki, Senda, Toshiya, Abe, Ikuro
Publicado 2018

Human Oxygenase Variants Employing a Single Protein Fe(II) Ligand Are Catalytically Active

por Brasnett, Amelia, Pfeffer, Inga, Brewitz, Lennart, Chowdhury, Rasheduzzaman, Nakashima, Yu, Tumber, Anthony, McDonough, Michael A., Schofield, Christopher J.
Publicado 2021

Prevention of Acute Upper Respiratory Infections by Consumption of Catechins in Healthcare Workers: A Randomized, Placebo-Controlled Trial

por Furushima, Daisuke, Nishimura, Takuma, Takuma, Norikata, Iketani, Ryo, Mizuno, Tomohito, Matsui, Yuji, Yamaguchi, Tohru, Nakashima, Yu, Yamamoto, Shinji, Hibi, Masanobu, Yamada, Hiroshi
Publicado 2019

Structural Basis of Prolyl Hydroxylase Domain Inhibition by Molidustat

por Figg, William D., McDonough, Michael A., Chowdhury, Rasheduzzaman, Nakashima, Yu, Zhang, Zhihong, Holt‐Martyn, James P., Krajnc, Alen, Schofield, Christopher J.
Publicado 2021

Physiological and Psychological Effects of Volatile Organic Compounds from Dried Common Rush (Juncus effusus L. var. decipiens Buchen.) on Humans

por Sun, Minkai, Nakashima, Taisuke, Yoshimura, Yuri, Honden, Akiyoshi, Nakagawa, Toshinori, Nakashima, Yu, Kawaguchi, Makoto, Takamori, Yukimitsu, Koshi, Yoshitaka, Sawada, Rimpei, Nishida, Shinsuke, Ohnuki, Koichiro, Shimizu, Kuniyoshi
Publicado 2022

Specific expression of MUC21 in micropapillary elements of lung adenocarcinomas – Implications for the progression of EGFR-mutated lung adenocarcinomas

por Matsumura, Mai, Okudela, Koji, Nakashima, Yu, Mitsui, Hideaki, Denda-Nagai, Kaori, Suzuki, Takehisa, Arai, Hiromasa, Umeda, Shigeaki, Tateishi, Yoko, Koike, Chihiro, Kataoka, Toshiaki, Irimura, Tatsuro, Ohashi, Kenichi
Publicado 2019

5-Substituted Pyridine-2,4-dicarboxylate Derivatives Have Potential for Selective Inhibition of Human Jumonji-C Domain-Containing Protein 5

por Brewitz, Lennart, Nakashima, Yu, Piasecka, Sonia K., Salah, Eidarus, Fletcher, Sally C., Tumber, Anthony, Corner, Thomas P., Kennedy, Tristan J., Fiorini, Giorgia, Thalhammer, Armin, Christensen, Kirsten E., Coleman, Mathew L., Schofield, Christopher J.
Publicado 2023

Structure-guided optimisation of N-hydroxythiazole-derived inhibitors of factor inhibiting hypoxia-inducible factor-α

por Corner, Thomas P., Teo, Ryan Z. R., Wu, Yue, Salah, Eidarus, Nakashima, Yu, Fiorini, Giorgia, Tumber, Anthony, Brasnett, Amelia, Holt-Martyn, James P., Figg, William D., Zhang, Xiaojin, Brewitz, Lennart, Schofield, Christopher J.
Publicado 2023

A human protein hydroxylase that accepts D-residues

por Choi, Hwanho, Hardy, Adam P., Leissing, Thomas M., Chowdhury, Rasheduzzaman, Nakashima, Yu, Ge, Wei, Markoulides, Marios, Scotti, John S., Gerken, Philip A., Thorbjornsrud, Helen, Kang, Dahye, Hong, Sungwoo, Lee, Joongoo, McDonough, Michael A., Park, Hwangseo, Schofield, Christopher J.
Publicado 2020

Identification of a diarylpentanoid-producing polyketide synthase revealing an unusual biosynthetic pathway of 2-(2-phenylethyl)chromones in agarwood

por Wang, Xiao-Hui, Gao, Bo-Wen, Nakashima, Yu, Mori, Takahiro, Zhang, Zhong-Xiu, Kodama, Takeshi, Lee, Yuan-E, Zhang, Ze-Kun, Wong, Chin-Piow, Liu, Qian-Qian, Qi, Bo-Wen, Wang, Juan, Li, Jun, Liu, Xiao, Abe, Ikuro, Morita, Hiroyuki, Tu, Peng-Fei, Shi, She-Po
Publicado 2022