Transport proteins of parasitic protists and their role in nutrient salvage

por Dean, Paul, Major, Peter, Nakjang, Sirintra, Hirt, Robert P., Embley, T. Martin
Publicado 2014

A Novel Extracellular Metallopeptidase Domain Shared by Animal Host-Associated Mutualistic and Pathogenic Microbes

por Nakjang, Sirintra, Ndeh, Didier A., Wipat, Anil, Bolam, David N., Hirt, Robert P.
Publicado 2012

Patterns of prokaryotic lateral gene transfers affecting parasitic microbial eukaryotes

por Alsmark, Cecilia, Foster, Peter G, Sicheritz-Ponten, Thomas, Nakjang, Sirintra, Martin Embley, T, Hirt, Robert P
Publicado 2013

FOXA1 regulates androgen receptor variant activity in models of castrate-resistant prostate cancer

por Jones, Dominic, Wade, Mark, Nakjang, Sirintra, Chaytor, Lewis, Grey, James, Robson, Craig N., Gaughan, Luke
Publicado 2015

Identification of TIAM1 as a Potential Synthetic-Lethal-like Gene in a Defined Subset of Hepatocellular Carcinoma

por Permtermsin, Chalermsin, Lalchungnunga, H, Nakjang, Sirintra, Casement, John, Ogle, Laura Frances, Reeves, Helen L., Strathdee, Gordon, Shukla, Ruchi
Publicado 2023

Differential regulation of the androgen receptor by protein phosphatase regulatory subunits

por Grey, James, Jones, Dominic, Wilson, Laura, Nakjang, Sirintra, Clayton, Jake, Temperley, Richard, Clark, Emma, Gaughan, Luke, Robson, Craig
Publicado 2017

The novel anti-androgen candidate galeterone targets deubiquitinating enzymes, USP12 and USP46, to control prostate cancer growth and survival

por McClurg, Urszula L., Azizyan, Mahsa, Dransfield, Daniel T., Namdev, Nivedita, Chit, Nay C.T.H., Nakjang, Sirintra, Robson, Craig N.
Publicado 2018

A novel CRISPR-engineered prostate cancer cell line defines the AR-V transcriptome and identifies PARP inhibitor sensitivities

por Kounatidou, Evangelia, Nakjang, Sirintra, McCracken, Stuart R C, Dehm, Scott M, Robson, Craig N, Jones, Dominic, Gaughan, Luke
Publicado 2019

Nanoparticle-mediated targeting of the fusion gene RUNX1/ETO in t(8;21)-positive acute myeloid leukaemia

por Issa, Hasan, Swart, Laura E., Rasouli, Milad, Ashtiani, Minoo, Nakjang, Sirintra, Jyotsana, Nidhi, Schuschel, Konstantin, Heuser, Michael, Blair, Helen, Heidenreich, Olaf
Publicado 2023

Reduction and Expansion in Microsporidian Genome Evolution: New Insights from Comparative Genomics

por Nakjang, Sirintra, Williams, Tom A., Heinz, Eva, Watson, Andrew K., Foster, Peter G., Sendra, Kacper M., Heaps, Sarah E., Hirt, Robert P., Martin Embley, T.
Publicado 2013

A Recent Whole-Genome Duplication Divides Populations of a Globally Distributed Microsporidian

por Williams, Tom A., Nakjang, Sirintra, Campbell, Scott E., Freeman, Mark A., Eydal, Matthías, Moore, Karen, Hirt, Robert P., Embley, T. Martin, Williams, Bryony A. P.
Publicado 2016

Development and exploitation of a novel mutant androgen receptor modelling strategy to identify new targets for advanced prostate cancer therapy

por O'Neill, Daniel, Jones, Dominic, Wade, Mark, Grey, James, Nakjang, Sirintra, Guo, Wenrui, Cork, David, Davies, Barry R., Wedge, Steve R., Robson, Craig N., Gaughan, Luke
Publicado 2015

Identification of a novel K311 ubiquitination site critical for androgen receptor transcriptional activity

por McClurg, Urszula L., Cork, David M.W., Darby, Steven, Ryan-Munden, Claudia A., Nakjang, Sirintra, Mendes Côrtes, Leticia, Treumann, Achim, Gaughan, Luke, Robson, Craig N.
Publicado 2017

Transporter gene acquisition and innovation in the evolution of Microsporidia intracellular parasites

por Dean, P., Sendra, K. M., Williams, T. A., Watson, A. K., Major, P., Nakjang, S., Kozhevnikova, E., Goldberg, A. V., Kunji, E. R. S., Hirt, R. P., Embley, T. M.
Publicado 2018

Phase II-like murine trial identifies synergy between dexamethasone and dasatinib in T-cell acute lymphoblastic leukemia

por Shi, Yuzhe, Beckett, Melanie C., Blair, Helen J., Tirtakusuma, Ricky, Nakjang, Sirintra, Enshaei, Amir, Halsey, Christina, Vormoor, Josef, Heidenreich, Olaf, Krippner-Heidenreich, Anja, van Delft, Frederik W.
Publicado 2020

Plasma Membrane-Located Purine Nucleotide Transport Proteins Are Key Components for Host Exploitation by Microsporidian Intracellular Parasites

por Heinz, Eva, Hacker, Christian, Dean, Paul, Mifsud, John, Goldberg, Alina V., Williams, Tom A., Nakjang, Sirintra, Gregory, Alison, Hirt, Robert P., Lucocq, John M., Kunji, Edmund R. S., Embley, T. Martin
Publicado 2014

Epigenome-wide analysis reveals functional modulators of drug sensitivity and post-treatment survival in chronic lymphocytic leukaemia

por Barrow, Timothy M., Nakjang, Sirintra, Lafta, Fadhel, Bilotkach, Kateryna, Woodhouse, Laura, Junge, Gesa, Tudhope, Susan J., Wallis, Jonathan P., Marr, Helen, Marshall, Scott, Bown, Nick, Willmore, Elaine, Strathdee, Gordon
Publicado 2020

CDC20 Is Regulated by the Histone Methyltransferase, KMT5A, in Castration-Resistant Prostate Cancer

por Alebady, Zainab A. H., Azizyan, Mahsa, Nakjang, Sirintra, Lishman-Walker, Emma, Al-Kharaif, Dhuha, Walker, Scott, Choo, Hui Xian, Garnham, Rebecca, Scott, Emma, Johnson, Katya L., Robson, Craig N., Coffey, Kelly
Publicado 2023

Evolutionary conservation and in vitro reconstitution of microsporidian iron–sulfur cluster biosynthesis

por Freibert, Sven-A., Goldberg, Alina V., Hacker, Christian, Molik, Sabine, Dean, Paul, Williams, Tom A., Nakjang, Sirintra, Long, Shaojun, Sendra, Kacper, Bill, Eckhard, Heinz, Eva, Hirt, Robert P., Lucocq, John M, Embley, T. Martin, Lill, Roland
Publicado 2017

Characterisation of the genomic landscape of CRLF2‐rearranged acute lymphoblastic leukemia

por Russell, Lisa J., Jones, Lisa, Enshaei, Amir, Tonin, Stefano, Ryan, Sarra L., Eswaran, Jeyanthy, Nakjang, Sirintra, Papaemmanuil, Elli, Tubio, Jose M. C., Fielding, Adele K., Vora, Ajay, Campbell, Peter J., Moorman, Anthony V., Harrison, Christine J.
Publicado 2017