Rapamycin and Chloroquine: The In Vitro and In Vivo Effects of Autophagy-Modifying Drugs Show Promising Results in Valosin Containing Protein Multisystem Proteinopathy

por Nalbandian, Angèle, Llewellyn, Katrina J., Nguyen, Christopher, Yazdi, Puya G., Kimonis, Virginia E.
Publicado 2015

Exercise Training Reverses Skeletal Muscle Atrophy in an Experimental Model of VCP Disease

por Nalbandian, Angèle, Nguyen, Christopher, Katheria, Veeral, Llewellyn, Katrina J., Badadani, Mallikarjun, Caiozzo, Vincent, Kimonis, Virginia E.
Publicado 2013

A Fine Balance of Dietary Lipids Improves Pathology of a Murine Model of VCP-Associated Multisystem Proteinopathy

por Llewellyn, Katrina J., Walker, Naomi, Nguyen, Christopher, Tan, Baichang, BenMohamed, Lbachir, Kimonis, Virginia E., Nalbandian, Angèle
Publicado 2015

Potential adverse effects of ciprofloxacin and tetracycline on ARPE-19 cell lines

por Salimiaghdam, Nasim, Singh, Lata, Schneider, Kevin, Nalbandian, Angele, Chwa, Marilyn, Atilano, Shari R, Bao, Andrea, Kenney, M Cristina
Publicado 2020

Effects of fluoroquinolones and tetracyclines on mitochondria of human retinal MIO-M1 cells

por Salimiaghdam, Nasim, Singh, Lata, Schneider, Kevin, Chwa, Marilyn, Atilano, Shari R., Nalbandian, Angele, Limb, G. Astrid, Kenney, M. Cristina
Publicado 2022

Myogenic differentiation of VCP disease-induced pluripotent stem cells: A novel platform for drug discovery

por Llewellyn, Katrina J., Nalbandian, Angèle, Weiss, Lan N., Chang, Isabela, Yu, Howard, Khatib, Bibo, Tan, Baichang, Scarfone, Vanessa, Kimonis, Virginia E.
Publicado 2017

VCP Associated Inclusion Body Myopathy and Paget Disease of Bone Knock-In Mouse Model Exhibits Tissue Pathology Typical of Human Disease

por Badadani, Mallikarjun, Nalbandian, Angèle, Watts, Giles D., Vesa, Jouni, Kitazawa, Masashi, Su, Hailing, Tanaja, Jasmin, Dec, Eric, Wallace, Douglas C., Mukherjee, Jogeshwar, Caiozzo, Vincent, Warman, Matthew, Kimonis, Virginia E.
Publicado 2010

The Homozygote VCP(R155H/R155H) Mouse Model Exhibits Accelerated Human VCP-Associated Disease Pathology

por Nalbandian, Angèle, Llewellyn, Katrina J., Kitazawa, Masashi, Yin, Hong Z., Badadani, Mallikarjun, Khanlou, Negar, Edwards, Robert, Nguyen, Christopher, Mukherjee, Jogeshwar, Mozaffar, Tahseen, Watts, Giles, Weiss, John, Kimonis, Virginia E.
Publicado 2012

Pathogenic variants of Valosin-containing protein induce lysosomal damage and transcriptional activation of autophagy regulators in neuronal cells

por Ferrari, Veronica, Cristofani, Riccardo, Cicardi, Maria E., Tedesco, Barbara, Crippa, Valeria, Chierichetti, Marta, Casarotto, Elena, Cozzi, Marta, Mina, Francesco, Galbiati, Mariarita, Piccolella, Margherita, Carra, Serena, Vaccari, Thomas, Nalbandian, Angele, Kimonis, Virginia, Fortuna, Tyler R., Pandey, Udai B., Gagliani, Maria C., Cortese, Katia, Rusmini, Paola, Poletti, Angelo
Publicado 2022