Uncovering the complexities of biological structures with network-based learning: An application in SARS-CoV-2

por Faghri, Faraz, Nalls, Mike A.
Publicado 2021

Mendelian Randomization — the Key to Understanding Aspects of Parkinson's Disease Causation?

por Noyce, Alastair J., Nalls, Mike A.
Publicado 2015

Association of red cell distribution width with all-cause and cardiovascular-specific mortality in African American and white adults: a prospective cohort study

por Tajuddin, Salman M., Nalls, Mike A., Zonderman, Alan B., Evans, Michele K.
Publicado 2017

The Parkinson’s phenome—traits associated with Parkinson’s disease in a broadly phenotyped cohort

por Heilbron, Karl, Noyce, Alastair J., Fontanillas, Pierre, Alipanahi, Babak, Nalls, Mike A., Cannon, Paul
Publicado 2019

Genetics of NLRP3 suggests lack of involvement and inefficient druggability in Parkinson’s disease

por Senkevich, Konstantin, Liu, Lang, Alvarado, Chelsea X., Leonard, Hampton L., Nalls, Mike A., Gan-Or, Ziv
Publicado 2023

Federated Learning for multi-omics: a performance evaluation in Parkinson’s disease

por Danek, Benjamin, Makarious, Mary B., Dadu, Anant, Vitale, Dan, Nalls, Mike A, Sun, Jimeng, Faghri, Faraz
Publicado 2023

Moving beyond neurons: the role of cell type-specific gene regulation in Parkinson’s disease heritability

por Reynolds, Regina H., Botía, Juan, Nalls, Mike A., Hardy, John, Gagliano Taliun, Sarah A., Ryten, Mina
Publicado 2019

Human brain single nucleus cell type enrichments in neurodegenerative diseases

por Alvarado, Chelsea X, Weller, Cory A., Johnson, Nicholas, Leonard, Hampton L., Singleton, Andrew B., Reed, Xylena, Blauewendraat, Cornelis, Nalls, Mike A
Publicado 2023

Finnish Parkinson’s disease study integrating protein-protein interaction network data with exome sequencing analysis

por Siitonen, Ari, Kytövuori, Laura, Nalls, Mike A., Gibbs, Raphael, Hernandez, Dena G., Ylikotila, Pauli, Peltonen, Markku, Singleton, Andrew B., Majamaa, Kari
Publicado 2019

A population scale analysis of rare SNCA variation in the UK Biobank

por Blauwendraat, Cornelis, Makarious, Mary B., Leonard, Hampton L., Bandres-Ciga, Sara, Iwaki, Hirotaka, Nalls, Mike A., Noyce, Alastair J., Singleton, Andrew B.
Publicado 2020

Proteomics and Epidemiological Models of Human Aging

por Ubaida-Mohien, Ceereena, Moaddel, Ruin, Moore, Ann Zenobia, Kuo, Pei-Lun, Faghri, Faraz, Tharakan, Ravi, Tanaka, Toshiko, Nalls, Mike A., Ferrucci, Luigi
Publicado 2021

Coding and Noncoding Variation in LRRK2 and Parkinson's Disease Risk

por Lake, Julie, Reed, Xylena, Langston, Rebekah G., Nalls, Mike A., Gan‐Or, Ziv, Cookson, Mark R., Singleton, Andrew B., Blauwendraat, Cornelis, Leonard, Hampton L.
Publicado 2021

Functionalization of the TMEM175 p.M393T variant as a risk factor for Parkinson disease

por Jinn, Sarah, Blauwendraat, Cornelis, Toolan, Dawn, Gretzula, Cheryl A, Drolet, Robert E, Smith, Sean, Nalls, Mike A, Marcus, Jacob, Singleton, Andrew B, Stone, David J
Publicado 2019

Sequential screening nominates the Parkinson's disease associated kinase LRRK2 as a regulator of Clathrin-mediated endocytosis

por Heaton, George R., Landeck, Natalie, Mamais, Adamantios, Nalls, Mike A., Nixon-Abell, Jonathon, Kumaran, Ravindran, Beilina, Alexandra, Pellegrini, Laura, Li, Yan, Harvey, Kirsten, Cookson, Mark R.
Publicado 2020

Unhealthy Behaviours and Risk of Parkinson’s Disease: A Mendelian Randomisation Study

por Heilbron, Karl, Jensen, Melanie P., Bandres-Ciga, Sara, Fontanillas, Pierre, Blauwendraat, Cornelis, Nalls, Mike A., Singleton, Andrew B., Smith, George Davey, Cannon, Paul, Noyce, Alastair J.
Publicado 2021

Polygenic risk of Parkinson disease is correlated with disease age at onset

por Escott‐Price, Valentina, Nalls, Mike A., Morris, Huw R., Lubbe, Steven, Brice, Alexis, Gasser, Thomas, Heutink, Peter, Wood, Nicholas W., Hardy, John, Singleton, Andrew B., Williams, Nigel M.
Publicado 2015

Mendelian Randomization Study Shows No Causal Relationship Between Circulating Urate Levels and Parkinson’s Disease

por Kia, Demis A., Noyce, Alastair J., White, Jon, Speed, Doug, Nicolas, Aude, Burgess, Stephen, Lawlor, Debbie A., Smith, George Davey, Singleton, Andrew, Nalls, Mike A., Sofat, Reecha, Wood, Nicholas W.
Publicado 2018

omicSynth: an Open Multi-omic Community Resource for Identifying Druggable Targets across Neurodegenerative Diseases

por Alvarado, Chelsea X., Makarious, Mary B., Weller, Cory A., Vitale, Dan, Koretsky, Mathew J., Bandres-Ciga, Sara, Iwaki, Hirotaka, Levine, Kristin, Singleton, Andrew, Faghri, Faraz, Nalls, Mike A., Leonard, Hampton L.
Publicado 2023

Divergent patterns of healthy aging across human brain regions at single-cell resolution reveal links to neurodegenerative disease

por Duffy, Megan F., Ding, Jinhui, Langston, Rebekah G., Shah, Syed I., Nalls, Mike A., Scholz, Sonja W., Whitaker, D. Thad, Auluck, Pavan K., Marenco, Stefano, Gibbs, J. Raphael, Cookson, Mark R.
Publicado 2023

Plasma 24-metabolite Panel Predicts Preclinical Transition to Clinical Stages of Alzheimer’s Disease

por Fiandaca, Massimo S., Zhong, Xiaogang, Cheema, Amrita K., Orquiza, Michael H., Chidambaram, Swathi, Tan, Ming T., Gresenz, Carole Roan, FitzGerald, Kevin T., Nalls, Mike A., Singleton, Andrew B., Mapstone, Mark, Federoff, Howard J.
Publicado 2015