The Role of APOE and TREM2 in Alzheimer′s Disease—Current Understanding and Perspectives

por Wolfe, Cody M., Fitz, Nicholas F., Nam, Kyong Nyon, Lefterov, Iliya, Koldamova, Radosveta
Publicado 2018

RXR controlled regulatory networks identified in mouse brain counteract deleterious effects of Aβ oligomers

por Nam, Kyong Nyon, Mounier, Anais, Fitz, Nicholas F., Wolfe, Cody, Schug, Jonathan, Lefterov, Iliya, Koldamova, Radosveta
Publicado 2016

ABCA1 haplodeficiency affects the brain transcriptome following traumatic brain injury in mice expressing human APOE isoforms

por Castranio, Emilie L., Wolfe, Cody M., Nam, Kyong Nyon, Letronne, Florent, Fitz, Nicholas F., Lefterov, Iliya, Koldamova, Radosveta
Publicado 2018

Trem2 deficiency differentially affects phenotype and transcriptome of human APOE3 and APOE4 mice

por Fitz, Nicholas F., Wolfe, Cody M., Playso, Brittany E., Biedrzycki, Richard J., Lu, Yi, Nam, Kyong Nyon, Lefterov, Iliya, Koldamova, Radosveta
Publicado 2020

Liver X receptor agonist treatment significantly affects phenotype and transcriptome of APOE3 and APOE4 Abca1 haplo-deficient mice

por Carter, Alexis Y., Letronne, Florent, Fitz, Nicholas F., Mounier, Anais, Wolfe, Cody M., Nam, Kyong Nyon, Reeves, Valerie L., Kamboh, Hafsa, Lefterov, Iliya, Koldamova, Radosveta
Publicado 2017

scMAPA: Identification of cell-type–specific alternative polyadenylation in complex tissues

por Bai, Yulong, Qin, Yidi, Fan, Zhenjiang, Morrison, Robert M, Nam, KyongNyon, Zarour, Hassane M, Koldamova, Radosveta, Padiath, Quasar Saleem, Kim, Soyeon, Park, Hyun Jung
Publicado 2022

APOE2 orchestrated differences in transcriptomic and lipidomic profiles of postmortem AD brain

por Lefterov, Iliya, Wolfe, Cody M., Fitz, Nicholas F., Nam, Kyong Nyon, Letronne, Florent, Biedrzycki, Richard J., Kofler, Julia, Han, Xianlin, Wang, Jianing, Schug, Jonathan, Koldamova, Radosveta
Publicado 2019

Paeonol attenuates inflammation-mediated neurotoxicity and microglial activation

por Nam, Kyong Nyon, Woo, Byung-Cheol, Moon, Sang-Kwan, Park, Seong-Uk, Park, Joo-young, Hwang, Jae-Woong, Bae, Hyung-Sup, Ko, Chang-Nam, Lee, Eunjoo Hwang
Publicado 2013

Effect of high fat diet on phenotype, brain transcriptome and lipidome in Alzheimer’s model mice

por Nam, Kyong Nyon, Mounier, Anais, Wolfe, Cody M., Fitz, Nicholas F., Carter, Alexis Y., Castranio, Emilie L., Kamboh, Hafsa I., Reeves, Valerie L., Wang, Jianing, Han, Xianlin, Schug, Jonathan, Lefterov, Iliya, Koldamova, Radosveta
Publicado 2017

Phospholipids of APOE lipoproteins activate microglia in an isoform-specific manner in preclinical models of Alzheimer’s disease

por Fitz, Nicholas F., Nam, Kyong Nyon, Wolfe, Cody M., Letronne, Florent, Playso, Brittany E., Iordanova, Bistra E., Kozai, Takashi D. Y., Biedrzycki, Richard J., Kagan, Valerian E., Tyurina, Yulia Y., Han, Xianlin, Lefterov, Iliya, Koldamova, Radosveta
Publicado 2021