Tricyclic analogues of epidithiodioxopiperazine alkaloids with promising in vitro and in vivo antitumor activity

por Baumann, Marcus, Dieskau, André P., Loertscher, Brad M., Walton, Mary C., Nam, Sangkil, Xie, Jun, Horne, David, Overman, Larry E.
Publicado 2015

A novel 7-bromoindirubin with potent anticancer activity suppresses survival of human melanoma cells associated with inhibition of STAT3 and Akt signaling

por Liu, Lucy, Kritsanida, Marina, Magiatis, Prokopios, Gaboriaud, Nicolas, Wang, Yan, Wu, Jun, Buettner, Ralf, Yang, Fan, Nam, Sangkil, Skaltsounis, Leandros, Jove, Richard
Publicado 2012

Spirooxindole Derivative SOID-8 Induces Apoptosis Associated with Inhibition of JAK2/STAT3 Signaling in Melanoma Cells

por Tian, Yan, Nam, Sangkil, Liu, Lucy, Yakushijin, Fumiko, Yakushijin, Kenichi, Buettner, Ralf, Liang, Wei, Yang, Fan, Ma, Yuelong, Horne, David, Jove, Richard
Publicado 2012

A Novel Berbamine Derivative Inhibits Cell Viability and Induces Apoptosis in Cancer Stem-Like Cells of Human Glioblastoma, via Up-Regulation of miRNA-4284 and JNK/AP-1 Signaling

por Yang, Fan, Nam, Sangkil, Brown, Christine E., Zhao, Robin, Starr, Renate, Horne, David A., Malkas, Linda H., Jove, Richard, Hickey, Robert J.
Publicado 2014

Targeting the non‐ATP‐binding pocket of the MAP kinase p38γ mediates a novel mechanism of cytotoxicity in cutaneous T‐cell lymphoma (CTCL)

por Zhang, Xu Hannah, Chen, Chih‐Hong, Li, Hongzhi, Hsiang, Jack, Wu, Xiwei, Hu, Weidong, Horne, David, Nam, Sangkil, Shively, Jack, Rosen, Steven T.
Publicado 2021

Multi-Kinase Inhibitor with Anti-p38γ Activity in Cutaneous T-Cell Lymphoma

por Zhang, Xu Hannah, Nam, Sangkil, Wu, Jun, Chen, Chih-Hong, Liu, Xuxiang, Li, Hongzhi, McKeithan, Timothy, Gong, Qiang, Chan, Wing C., Yin, Hongwei Holly, Yuan, Yate-Ching, Pillai, Raju, Querfeld, Christiane, Horne, David, Chen, Yuan, Rosen, Steven T.
Publicado 2018