Rapid glycolytic activation accompanying innate immune responses: mechanisms and function

por Namgaladze, Dmitry, Brüne, Bernhard
Publicado 2023

Pharmacological Activation of p53 during Human Monocyte to Macrophage Differentiation Attenuates Their Pro-Inflammatory Activation by TLR4, TLR7 and TLR8 Agonists

por Namgaladze, Dmitry, Brüne, Bernhard
Publicado 2021

AICAR inhibits NFκB DNA binding independently of AMPK to attenuate LPS-triggered inflammatory responses in human macrophages

por Kirchner, Johannes, Brüne, Bernhard, Namgaladze, Dmitry
Publicado 2018

ER-Mitochondria Communication in Cells of the Innate Immune System

por Namgaladze, Dmitry, Khodzhaeva, Vera, Brüne, Bernhard
Publicado 2019

Exploring the Role of ATP-Citrate Lyase in the Immune System

por Dominguez, Monica, Brüne, Bernhard, Namgaladze, Dmitry
Publicado 2021

Interplay of Nrf2 and BACH1 in inducing ferroportin expression and enhancing resistance of human macrophages towards ferroptosis

por Namgaladze, Dmitry, Fuhrmann, Dominik C., Brüne, Bernhard
Publicado 2022

Impact of ATP-citrate lyase catalytic activity and serine 455 phosphorylation on histone acetylation and inflammatory responses in human monocytic THP-1 cells

por Dominguez, Monica, Truemper, Verena, Mota, Ana Carolina, Brüne, Bernhard, Namgaladze, Dmitry
Publicado 2022

AMPK-independent inhibition of human macrophage ER stress response by AICAR

por Boß, Marcel, Newbatt, Yvette, Gupta, Sahil, Collins, Ian, Brüne, Bernhard, Namgaladze, Dmitry
Publicado 2016

Mitofusin 2 Deficiency Causes Pro-Inflammatory Effects in Human Primary Macrophages

por Khodzhaeva, Vera, Schreiber, Yannick, Geisslinger, Gerd, Brandes, Ralf P., Brüne, Bernhard, Namgaladze, Dmitry
Publicado 2021

Polarization of Human Macrophages by Interleukin-4 Does Not Require ATP-Citrate Lyase

por Namgaladze, Dmitry, Zukunft, Sven, Schnütgen, Frank, Kurrle, Nina, Fleming, Ingrid, Fuhrmann, Dominik, Brüne, Bernhard
Publicado 2018

Inhibitors of Oxidative Phosphorylation Modulate Astrocyte Inflammatory Responses through AMPK-Dependent Ptgs2 mRNA Stabilization

por Astakhova, Alina, Chistyakov, Dmitry, Thomas, Dominique, Geisslinger, Gerd, Brüne, Bernhard, Sergeeva, Marina, Namgaladze, Dmitry
Publicado 2019

Lysosome-Dependent LXR and PPARδ Activation Upon Efferocytosis in Human Macrophages

por Mota, Ana Carolina, Dominguez, Monica, Weigert, Andreas, Snodgrass, Ryan G., Namgaladze, Dmitry, Brüne, Bernhard
Publicado 2021

AMP-Activated Protein Kinase Interacts with the Peroxisome Proliferator-Activated Receptor Delta to Induce Genes Affecting Fatty Acid Oxidation in Human Macrophages

por Kemmerer, Marina, Finkernagel, Florian, Cavalcante, Marcela Frota, Abdalla, Dulcineia Saes Parra, Müller, Rolf, Brüne, Bernhard, Namgaladze, Dmitry
Publicado 2015

A Novel Function for 15-Lipoxygenases in Cholesterol Homeostasis and CCL17 Production in Human Macrophages

por Snodgrass, Ryan G., Zezina, Ekaterina, Namgaladze, Dmitry, Gupta, Sahil, Angioni, Carlo, Geisslinger, Gerd, Lütjohann, Dieter, Brüne, Bernhard
Publicado 2018

Efferocytosis potentiates the expression of arachidonate 15-lipoxygenase (ALOX15) in alternatively activated human macrophages through LXR activation

por Snodgrass, Ryan G., Benatzy, Yvonne, Schmid, Tobias, Namgaladze, Dmitry, Mainka, Malwina, Schebb, Nils Helge, Lütjohann, Dieter, Brüne, Bernhard
Publicado 2020

Loss of HIF-1β in macrophages attenuates AhR/ARNT-mediated tumorigenesis in a PAH-driven tumor model

por Henke, Nina, Ferreirós, Nerea, Geisslinger, Gerd, Ding, Martina G., Essler, Silke, Fuhrmann, Dominik C., Geis, Theresa, Namgaladze, Dmitry, Dehne, Nathalie, Brüne, Bernhard
Publicado 2016

Differential expression of CD8 defines phenotypically distinct cytotoxic T cells in cancer and multiple sclerosis

por Burkard, Tobias, Herrero San Juan, Martina, Dreis, Caroline, Kiprina, Anastasiia, Namgaladze, Dmitry, Siebenbrodt, Kai, Luger, Sebastian, Foerch, Christian, Pfeilschifter, Josef M., Weigert, Andreas, Radeke, Heinfried H.
Publicado 2022

scFv-Anti-LDL(-)-Metal-Complex Multi-Wall Functionalized-Nanocapsules as a Promising Tool for the Prevention of Atherosclerosis Progression

por Cavalcante, Marcela Frota, Adorne, Márcia Duarte, Turato, Walter Miguel, Kemmerer, Marina, Uchiyama, Mayara Klimuk, Asbahr, Ana Carolina Cavazzin, Alves, Aline de Cristo Soares, Farsky, Sandra Helena Poliselli, Drewes, Carine, Spatti, Marina Cecília, Kazuma, Soraya Megumi, Boss, Marcel, Guterres, Silvia Stanisçuaski, Araki, Koiti, Brüne, Bernhard, Namgaladze, Dmitry, Pohlmann, Adriana Raffin, Abdalla, Dulcineia Saes Parra
Publicado 2021

LUBAC assembles a ubiquitin signaling platform at mitochondria for signal amplification and transport of NF‐κB to the nucleus

por Wu, Zhixiao, Berlemann, Lena A, Bader, Verian, Sehr, Dominik A, Dawin, Eva, Covallero, Alberto, Meschede, Jens, Angersbach, Lena, Showkat, Cathrin, Michaelis, Jonas B, Münch, Christian, Rieger, Bettina, Namgaladze, Dmitry, Herrera, Maria Georgina, Fiesel, Fabienne C, Springer, Wolfdieter, Mendes, Marta, Stepien, Jennifer, Barkovits, Katalin, Marcus, Katrin, Sickmann, Albert, Dittmar, Gunnar, Busch, Karin B, Riedel, Dietmar, Brini, Marisa, Tatzelt, Jörg, Cali, Tito, Winklhofer, Konstanze F
Publicado 2022

Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells

por Hitzel, Juliane, Lee, Eunjee, Zhang, Yi, Bibli, Sofia Iris, Li, Xiaogang, Zukunft, Sven, Pflüger, Beatrice, Hu, Jiong, Schürmann, Christoph, Vasconez, Andrea Estefania, Oo, James A., Kratzer, Adelheid, Kumar, Sandeep, Rezende, Flávia, Josipovic, Ivana, Thomas, Dominique, Giral, Hector, Schreiber, Yannick, Geisslinger, Gerd, Fork, Christian, Yang, Xia, Sigala, Fragiska, Romanoski, Casey E., Kroll, Jens, Jo, Hanjoong, Landmesser, Ulf, Lusis, Aldons J., Namgaladze, Dmitry, Fleming, Ingrid, Leisegang, Matthias S., Zhu, Jun, Brandes, Ralf P.
Publicado 2018