Hierarchical assembly of the MLL1 core complex regulates H3K4 methylation and is dependent on temperature and component concentration

por Namitz, Kevin E.W., Tan, Song, Cosgrove, Michael S.
Publicado 2023

Phase separation promotes a highly active oligomeric scaffold of the MLL1 core complex for regulation of histone H3K4 methylation

por Namitz, Kevin E.W., Showalter, Scott A., Cosgrove, Michael S.
Publicado 2023

Advances in direct detection of lysine methylation and acetylation by nuclear magnetic resonance using (13)C-enriched cofactors

por Fraser, Olivia A., Namitz, Kevin E.W., Showalter, Scott A.
Publicado 2023

Probing multiple enzymatic methylation events in real time with NMR spectroscopy

por Usher, Emery T., Namitz, Kevin E.W., Cosgrove, Michael S., Showalter, Scott A.
Publicado 2021

Structure analysis suggests Ess1 isomerizes the carboxy-terminal domain of RNA polymerase II via a bivalent anchoring mechanism

por Namitz, Kevin E. W., Zheng, Tongyin, Canning, Ashley J., Alicea-Velazquez, Nilda L., Castañeda, Carlos A., Cosgrove, Michael S., Hanes, Steven D.
Publicado 2021

Multistate structures of the MLL1-WRAD complex bound to H2B-ubiquitinated nucleosome

por Rahman, Sanim, Hoffmann, Niklas A., Worden, Evan J., Smith, Marissa L., Namitz, Kevin E. W., Knutson, Bruce A., Cosgrove, Michael S., Wolberger, Cynthia
Publicado 2022

Coevolution of the Ess1-CTD axis in polar fungi suggests a role for phase separation in cold tolerance

por Palumbo, Ryan J., McKean, Nathan, Leatherman, Erinn, Namitz, Kevin E. W., Connell, Laurie, Wolfe, Aaron, Moody, Kelsey, Gostinčar, Cene, Gunde-Cimerman, Nina, Bah, Alaji, Hanes, Steven D.
Publicado 2022