Discovery of aryl sulfonamide-selective Nav1.7 inhibitors with a highly hydrophobic ethanoanthracene core

por Wang, Jin-tao, Zheng, Yue-ming, Chen, Yue-ting, Gu, Min, Gao, Zhao-bing, Nan, Fa-jun
Publicado 2019

Structural analysis of inhibition of E. coli methionine aminopeptidase: implication of loop adaptability in selective inhibition of bacterial enzymes

por Ma, Ze-Qiang, Xie, Sheng-Xue, Huang, Qing-Qing, Nan, Fa-Jun, Hurley, Thomas D, Ye, Qi-Zhuang
Publicado 2007

Discovery of 9,11-Seco-Cholesterol Derivatives as Novel FXR Antagonists

por Zhou, Jia-Xu, Li, Cui-Na, Liu, Ya-Meng, Lin, Su-Qin, Wang, Ying, Xie, Cen, Nan, Fa-Jun
Publicado 2022

Berberine derivatives with a long alkyl chain branched by hydroxyl group and methoxycarbonyl group at 9-position show improved anti-proliferation activity and membrane permeability...

por Liu, Yi, Zhu, Ke-xin, Cao, Lei, Xie, Zhi-fu, Gu, Min, Lü, Wei, Li, Jing-ya, Nan, Fa-jun
Publicado 2020

Synthesis and Antiviral Activity of Conformational Analogues of Leucamide A

por Wang, Wen-Long, Chen, Hai-Jun, Ma, Wei-Ping, Gu, Min, Fan, Min-Zhi, Li, Jing-Ya, Feng, Bainian, Nan, Fa-Jun
Publicado 2012

Structural insights into ligand recognition and activation of the medium-chain fatty acid-sensing receptor GPR84

por Liu, Heng, Zhang, Qing, He, Xinheng, Jiang, Mengting, Wang, Siwei, Yan, Xiaoci, Cheng, Xi, Liu, Yang, Nan, Fa-Jun, Xu, H. Eric, Xie, Xin, Yin, Wanchao
Publicado 2023

Author Correction: Structural insights into ligand recognition and activation of the medium-chain fatty acid-sensing receptor GPR84

por Liu, Heng, Zhang, Qing, He, Xinheng, Jiang, Mengting, Wang, Siwei, Yan, Xiaoci, Cheng, Xi, Liu, Yang, Nan, Fa-Jun, Xu, H. Eric, Xie, Xin, Yin, Wanchao
Publicado 2023

High-Throughput Assay for Modulators of Mitochondrial Membrane Potential Identifies a Novel Compound With Beneficial Effects on db/db Mice

por Qiu, Bei-Ying, Turner, Nigel, Li, Yuan-Yuan, Gu, Min, Huang, Meng-Wei, Wu, Fang, Pang, Tao, Nan, Fa-Jun, Ye, Ji-Ming, Li, Jing-Ya, Li, Jia
Publicado 2010

GPR84 signaling promotes intestinal mucosal inflammation via enhancing NLRP3 inflammasome activation in macrophages

por Zhang, Qing, Chen, Lin-hai, Yang, Hui, Fang, You-chen, Wang, Si-wei, Wang, Min, Yuan, Qian-ting, Wu, Wei, Zhang, Yang-ming, Liu, Zhan-ju, Nan, Fa-jun, Xie, Xin
Publicado 2021

GPR84 regulates pulmonary inflammation by modulating neutrophil functions

por Wang, Si-wei, Zhang, Qing, Lu, Dan, Fang, You-chen, Yan, Xiao-ci, Chen, Jing, Xia, Zhi-kan, Yuan, Qian-ting, Chen, Lin-hai, Zhang, Yang-ming, Nan, Fa-jun, Xie, Xin
Publicado 2023

1H-2,3-Dihydroperimidine Derivatives: A New Class of Potent Protein Tyrosine Phosphatase 1B Inhibitors

por Wang, Wen-Long, Yang, Dong-Lin, Gao, Li-Xin, Tang, Chun-Lan, Ma, Wei-Ping, Ye, Hui-Hua, Zhang, Si-Qi, Zhao, Ya-Nan, Xu, Hao-Jie, Hu, Zhao, Chen, Xia, Fan, Wen-Hua, Chen, Hai-Jun, Li, Jing-Ya, Nan, Fa-Jun, Li, Jia, Feng, Bainian
Publicado 2013

Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma

por Zhou, Yu-bo, Zhang, Yang-ming, Huang, Hong-hui, Shen, Li-jing, Han, Xiao-feng, Hu, Xiao-bei, Yu, Song-da, Gao, An-hui, Sheng, Li, Su, Ming-bo, Wei, Xiao-li, Zhang, Yue, Zhang, Yi-fan, Gao, Zhi-wei, Chen, Xiao-yan, Nan, Fa-jun, Li, Jia, Hou, Jian
Publicado 2021