Chimeric Antigen Receptors Directed at Mutant KRAS Exhibit an Inverse Relationship Between Functional Potency and Neoantigen Selectivity

por Tokatlian, Talar, Asuelime, Grace E., Naradikian, Martin S., Mock, Jee-Young, Daris, Mark E., Martin, Aaron D., Toledo Warshaviak, Dora, Kamb, Alexander, Hamburger, Agnes E.
Publicado 2022

HLA-A∗02-gated safety switch for cancer therapy has exquisite specificity for its allelic target antigen

por Mock, Jee-Young, Winters, Aaron, Riley, Timothy P., Bruno, Richele, Naradikian, Martin S., Sharma, Shruti, Jette, Claudia A., Elshimali, Ryan, Gahrs, Casey, Toledo-Warshaviak, Dora, West, Anthony P., Kamb, Alexander, Hamburger, Agnes E.
Publicado 2022

Mesothelin-specific CAR-T cell therapy that incorporates an HLA-gated safety mechanism selectively kills tumor cells

por Tokatlian, Talar, Asuelime, Grace E, Mock, Jee-Young, DiAndreth, Breanna, Sharma, Shruti, Toledo Warshaviak, Dora, Daris, Mark E, Bolanos, Kristian, Luna, Breanna L, Naradikian, Martin S, Deshmukh, Kiran, Hamburger, Agnes E, Kamb, Alexander
Publicado 2022

Tumor cells fail to present MHC-II–restricted epitopes derived from oncogenes to CD4(+) T cells

por Brightman, Spencer E., Naradikian, Martin S., Thota, Rukman R., Becker, Angelica, Montero, Leslie, Bahmanof, Milad, Premlal, Ashmitaa Logandha Ramamoorthy, Greenbaum, Jason A., Peters, Bjoern, Cohen, Ezra E.W., Miller, Aaron M., Schoenberger, Stephen P.
Publicado 2023

Author Correction: Neoantigen-specific stem cell memory-like CD4(+) T cells mediate CD8(+) T cell-dependent immunotherapy of MHC class II-negative solid tumors

por Brightman, Spencer E., Becker, Angelica, Thota, Rukman R., Naradikian, Martin S., Chihab, Leila, Zavala, Karla Soria, Ramamoorthy Premlal, Ashmitaa Logandha, Griswold, Ryan Q., Dolina, Joseph S., Cohen, Ezra E. W., Miller, Aaron M., Peters, Bjoern, Schoenberger, Stephen P.
Publicado 2023

Neoantigen-specific stem cell memory-like CD4(+) T cells mediate CD8(+) T cell-dependent immunotherapy of MHC class II-negative solid tumors

por Brightman, Spencer E., Becker, Angelica, Thota, Rukman R., Naradikian, Martin S., Chihab, Leila, Zavala, Karla Soria, Ramamoorthy Premlal, Ashmitaa Logandha, Griswold, Ryan Q., Dolina, Joseph S., Cohen, Ezra E. W., Miller, Aaron M., Peters, Bjoern, Schoenberger, Stephen P.
Publicado 2023

Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses

por Pardi, Norbert, Hogan, Michael J., Naradikian, Martin S., Parkhouse, Kaela, Cain, Derek W., Jones, Letitia, Moody, M. Anthony, Verkerke, Hans P., Myles, Arpita, Willis, Elinor, LaBranche, Celia C., Montefiori, David C., Lobby, Jenna L., Saunders, Kevin O., Liao, Hua-Xin, Korber, Bette T., Sutherland, Laura L., Scearce, Richard M., Hraber, Peter T., Tombácz, István, Muramatsu, Hiromi, Ni, Houping, Balikov, Daniel A., Li, Charles, Mui, Barbara L., Tam, Ying K., Krammer, Florian, Karikó, Katalin, Polacino, Patricia, Eisenlohr, Laurence C., Madden, Thomas D., Hope, Michael J., Lewis, Mark G., Lee, Kelly K., Hu, Shiu-Lok, Hensley, Scott E., Cancro, Michael P., Haynes, Barton F., Weissman, Drew
Publicado 2018