High polygenic risk score is a risk factor associated with colorectal cancer based on data from the UK Biobank

por Yang, Mei, Narasimhan, Vagheesh M., Zhan, F. Benjamin
Publicado 2023

Human Knockout Carriers: Dead, Diseased, Healthy, or Improved?

por Narasimhan, Vagheesh M., Xue, Yali, Tyler-Smith, Chris
Publicado 2016

Understanding natural selection in Holocene Europe using multi-locus genotype identity scans

por Pandey, Devansh, Harris, Mariana, Garud, Nandita R., Narasimhan, Vagheesh M.
Publicado 2023

Metagenomic microbial community profiling using unique clade-specific marker genes

por Segata, Nicola, Waldron, Levi, Ballarini, Annalisa, Narasimhan, Vagheesh, Jousson, Olivier, Huttenhower, Curtis
Publicado 2012

BCFtools/RoH: a hidden Markov model approach for detecting autozygosity from next-generation sequencing data

por Narasimhan, Vagheesh, Danecek, Petr, Scally, Aylwyn, Xue, Yali, Tyler-Smith, Chris, Durbin, Richard
Publicado 2016

1,000 ancient genomes uncover 10,000 years of natural selection in Europe

por Le, Megan K., Smith, Olivia S., Akbari, Ali, Harpak, Arbel, Reich, David, Narasimhan, Vagheesh M.
Publicado 2022

Extensive Proliferation of a Subset of Differentiated, yet Plastic, Medial Vascular Smooth Muscle Cells Contributes to Neointimal Formation in Mouse Injury and Atherosclerosis Mode...

por Chappell, Joel, Harman, Jennifer L., Narasimhan, Vagheesh M., Yu, Haixiang, Foote, Kirsty, Simons, Benjamin D., Bennett, Martin R., Jørgensen, Helle F.
Publicado 2016

Deep learning based phenotyping of medical images improves power for gene discovery of complex disease

por Flynn, Brianna I., Javan, Emily M., Lin, Eugenia, Trutner, Zoe, Koenig, Karl, Anighoro, Kenoma O., Kun, Eucharist, Gupta, Alaukik, Singh, Tarjinder, Jayakumar, Prakash, Narasimhan, Vagheesh M.
Publicado 2023

The genetic architecture of the human skeletal form

por Kun, Eucharist, Javan, Emily M., Smith, Olivia, Gulamali, Faris, de la Fuente, Javier, Flynn, Brianna I., Vajrala, Kushal, Trutner, Zoe, Jayakumar, Prakash, Tucker-Drob, Elliot M., Sohail, Mashaal, Singh, Tarjinder, Narasimhan, Vagheesh M.
Publicado 2023

Transcriptional profiling defines dynamics of parasite tissue sequestration during malaria infection

por Pelle, Karell G, Oh, Keunyoung, Buchholz, Kathrin, Narasimhan, Vagheesh, Joice, Regina, Milner, Danny A, Brancucci, Nicolas MB, Ma, Siyuan, Voss, Till S, Ketman, Ken, Seydel, Karl B, Taylor, Terrie E, Barteneva, Natasha S, Huttenhower, Curtis, Marti, Matthias
Publicado 2015

Estimating the human mutation rate from autozygous segments reveals population differences in human mutational processes

por Narasimhan, Vagheesh M., Rahbari, Raheleh, Scally, Aylwyn, Wuster, Arthur, Mason, Dan, Xue, Yali, Wright, John, Trembath, Richard C., Maher, Eamonn R., van Heel, David A., Auton, Adam, Hurles, Matthew E., Tyler-Smith, Chris, Durbin, Richard
Publicado 2017

Inferring Developmental Stage Composition from Gene Expression in Human Malaria

por Joice, Regina, Narasimhan, Vagheesh, Montgomery, Jacqui, Sidhu, Amar Bir, Oh, Keunyoung, Meyer, Evan, Pierre-Louis, Willythssa, Seydel, Karl, Milner, Danny, Williamson, Kim, Wiegand, Roger, Ndiaye, Daouda, Daily, Johanna, Wirth, Dyann, Taylor, Terrie, Huttenhower, Curtis, Marti, Matthias
Publicado 2013

Enrichment of low-frequency functional variants revealed by whole-genome sequencing of multiple isolated European populations

por Xue, Yali, Mezzavilla, Massimo, Haber, Marc, McCarthy, Shane, Chen, Yuan, Narasimhan, Vagheesh, Gilly, Arthur, Ayub, Qasim, Colonna, Vincenza, Southam, Lorraine, Finan, Christopher, Massaia, Andrea, Chheda, Himanshu, Palta, Priit, Ritchie, Graham, Asimit, Jennifer, Dedoussis, George, Gasparini, Paolo, Palotie, Aarno, Ripatti, Samuli, Soranzo, Nicole, Toniolo, Daniela, Wilson, James F., Durbin, Richard, Tyler-Smith, Chris, Zeggini, Eleftheria
Publicado 2017

Correction: A restricted spectrum of missense KMT2D variants cause a multiple malformations disorder distinct from Kabuki syndrome

por Cuvertino, Sara, Hartill, Verity, Colyer, Alice, Garner, Terence, Nair, Nisha, Al-Gazali, Lihadh, Canham, Natalie, Faundes, Victor, Flinter, Frances, Hertecant, Jozef, Holder-Espinasse, Muriel, Jackson, Brian, Lynch, Sally Ann, Nadat, Fatima, Narasimhan, Vagheesh M., Peckham, Michelle, Sellers, Robert, Seri, Marco, Montanari, Francesca, Southgate, Laura, Squeo, Gabriella Maria, Trembath, Richard, van Heel, David, Venuto, Santina, Weisberg, Daniel, Stals, Karen, Ellard, Sian, Barton, Anne, Kimber, Susan J., Sheridan, Eamonn, Merla, Giuseppe, Stevens, Adam, Johnson, Colin A., Banka, Siddharth
Publicado 2020

A restricted spectrum of missense KMT2D variants cause a multiple malformations disorder distinct from Kabuki syndrome

por Cuvertino, Sara, Hartill, Verity, Colyer, Alice, Garner, Terence, Nair, Nisha, Al-Gazali, Lihadh, Canham, Natalie, Faundes, Victor, Flinter, Frances, Hertecant, Jozef, Holder-Espinasse, Muriel, Jackson, Brian, Lynch, Sally Ann, Nadat, Fatima, Narasimhan, Vagheesh M., Peckham, Michelle, Sellers, Robert, Seri, Marco, Montanari, Francesca, Southgate, Laura, Squeo, Gabriella Maria, Trembath, Richard, van Heel, David, Venuto, Santina, Weisberg, Daniel, Stals, Karen, Ellard, Sian, Barton, Anne, Kimber, Susan J., Sheridan, Eamonn, Merla, Giuseppe, Stevens, Adam, Johnson, Colin A., Banka, Siddharth
Publicado 2020