Limitations of Antibiotic MIC-Based PK-PD Metrics: Looking Back to Move Forward

por Landersdorfer, Cornelia B., Nation, Roger L.
Publicado 2021

Polymyxin Acute Kidney Injury: Dosing and Other Strategies to Reduce Toxicity

por Nation, Roger L., Rigatto, Maria Helena P., Falci, Diego R., Zavascki, Alexandre P.
Publicado 2019

Evaluation of Tobramycin and Ciprofloxacin as a Synergistic Combination Against Hypermutable Pseudomonas Aeruginosa Strains via Mechanism-Based Modelling

por Rees, Vanessa E., Bulitta, Jürgen B., Oliver, Antonio, Nation, Roger L., Landersdorfer, Cornelia B.
Publicado 2019

Teaching ‘Old’ Polymyxins New Tricks: New-Generation Lipopeptides Targeting Gram-Negative ‘Superbugs’

por Velkov, Tony, Roberts, Kade D., Nation, Roger L., Wang, Jiping, Thompson, Philip E., Li, Jian
Publicado 2014

Design and Evaluation of Novel Polymyxin Fluorescent Probes

por Yun, Bo, Roberts, Kade D., Thompson, Philip E., Nation, Roger L., Velkov, Tony, Li, Jian
Publicado 2017

Mortality, clinical and microbiological response following antibiotic therapy among patients with carbapenem-resistant Klebsiella pneumoniae infections (a meta-analysis dataset)

por Agyeman, Akosua A., Bergen, Phillip J., Rao, Gauri G., Nation, Roger L., Landersdorfer, Cornelia B.
Publicado 2019

Untargeted metabolomics analysis reveals key pathways responsible for the synergistic killing of colistin and doripenem combination against Acinetobacter baumannii

por Maifiah, Mohd Hafidz Mahamad, Creek, Darren J., Nation, Roger L., Forrest, Alan, Tsuji, Brian T., Velkov, Tony, Li, Jian
Publicado 2017

Personalizing Polymyxin B Dosing Using an Adaptive Feedback Control Algorithm

por Lakota, Elizabeth A., Landersdorfer, Cornelia B., Nation, Roger L., Li, Jian, Kaye, Keith S., Rao, Gauri G., Forrest, Alan
Publicado 2018

Mathematical modelling of vancomycin-resistant enterococci transmission during passive surveillance and active surveillance with contact isolation highlights the need to identify a...

por Cheah, Agnes Loo Yee, Cheng, Allen C., Spelman, Denis, Nation, Roger L., Kong, David C. M., McBryde, Emma S.
Publicado 2018

A secondary mode of action of polymyxins against Gram-negative bacteria involves the inhibition of NADH-quinone oxidoreductase activity

por Deris, Zakuan Z., Akter, Jesmin, Sivanesan, Sivashangarie, Roberts, Kade D., Thompson, Philip E., Nation, Roger L., Li, Jian, Velkov, Tony
Publicado 2013

Case-case-control study on factors associated with vanB vancomycin-resistant and vancomycin-susceptible enterococcal bacteraemia

por Cheah, Agnes Loo Yee, Peel, Trisha, Howden, Benjamin P, Spelman, Denis, Grayson, M Lindsay, Nation, Roger L, Kong, David CM
Publicado 2014

Molecular Characterization of Lipopolysaccharide Binding to Human α-1-Acid Glycoprotein

por Huang, Johnny X., Azad, Mohammad A. K., Yuriev, Elizabeth, Baker, Mark A., Nation, Roger L., Li, Jian, Cooper, Matthew A., Velkov, Tony
Publicado 2012

Polymyxin Resistance in Acinetobacter baumannii: Genetic Mutations and Transcriptomic Changes in Response to Clinically Relevant Dosage Regimens

por Cheah, Soon-Ee, Johnson, Matthew D., Zhu, Yan, Tsuji, Brian T., Forrest, Alan, Bulitta, Jurgen B., Boyce, John D., Nation, Roger L., Li, Jian
Publicado 2016

Transcriptomic Analysis of the Activity of a Novel Polymyxin against Staphylococcus aureus

por Zhao, Jinxin, Cheah, Soon-Ee, Roberts, Kade D., Nation, Roger L., Thompson, Philip E., Velkov, Tony, Du, Zongjun, Johnson, Matthew D., Li, Jian
Publicado 2016

Optimizing Polymyxin Combinations Against Resistant Gram-Negative Bacteria

por Bergen, Phillip J., Bulman, Zackery P., Landersdorfer, Cornelia B., Smith, Nicholas, Lenhard, Justin R., Bulitta, Jürgen B., Nation, Roger L., Li, Jian, Tsuji, Brian T.
Publicado 2015

Cure of Limb-Threatening XDR Pseudomonas aeruginosa Infection: Combining Genome Sequencing, Therapeutic Drug Level Monitoring, and Surgical Debridement

por Narayanasamy, Shanti, Nation, Roger L, Mahony, Andrew A, Grayson, M Lindsay, Kwong, Jason C, Sherry, Norelle L, Khumra, Sharmila, Ellis, Andrew G, Frauman, Albert G, Holmes, Natasha E
Publicado 2020

Penicillin G concentrations required for prophylaxis against Group A Streptococcus infection evaluated using a hollow fibre model and mathematical modelling

por Tait, Jessica R, Barnett, Timothy C, Rogers, Kate E, Lee, Wee Leng, Page-Sharp, Madhu, Manning, Laurens, Boyd, Ben J, Carapetis, Jonathan R, Nation, Roger L, Landersdorfer, Cornelia B
Publicado 2022

Probing the Penetration of Antimicrobial Polymyxin Lipopeptides into Gram-Negative Bacteria

por Deris, Zakuan Z., Swarbrick, James D., Roberts, Kade D., Azad, Mohammad A. K., Akter, Jesmin, Horne, Andrew. S., Nation, Roger L., Rogers, Kelly L., Thompson, Phillip E., Velkov, Tony, Li, Jian
Publicado 2014

Anthelmintic closantel enhances bacterial killing of polymyxin B against multidrug-resistant Acinetobacter baumannii

por Tran, Thien B., Cheah, Soon-Ee, Yu, Heidi H., Bergen, Phillip J., Nation, Roger L., Creek, Darren J., Purcell, Anthony, Forrest, Alan, Doi, Yohei, Song, Jiangning, Velkov, Tony, Li, Jian
Publicado 2015

Polymyxin Combinations Combat Escherichia coli Harboring mcr-1 and bla(NDM-5): Preparation for a Postantibiotic Era

por Bulman, Zackery P., Chen, Liang, Walsh, Thomas J., Satlin, Michael J., Qian, Yuli, Bulitta, Jürgen B., Peloquin, Charles A., Holden, Patricia N., Nation, Roger L., Li, Jian, Kreiswirth, Barry N., Tsuji, Brian T.
Publicado 2017