Differences in Transporters Rather than Drug Targets Are the Principal Determinants of the Different Innate Sensitivities of Trypanosoma congolense and Trypanozoon Subgenus Trypano...

por Ungogo, Marzuq A., Campagnaro, Gustavo D., Alghamdi, Ali H., Natto, Manal J., de Koning, Harry P.
Publicado 2022

In and out of the minor groove: interaction of an AT-rich DNA with the drug CD27

por Acosta-Reyes, Francisco J., Dardonville, Christophe, de Koning, Harry P., Natto, Manal, Subirana, Juan A., Campos, J. Lourdes
Publicado 2014

Novel flavanones with anti-trypanosomal activity isolated from Zambian and Tanzanian propolis samples

por Alenezi, Samya S., Natto, Manal J., Igoli, John O., Gray, Alexander I., Fearnley, James, Fearnley, Hugo, de Koning, Harry P., Watson, David G.
Publicado 2020

A Toxoplasma gondii Oxopurine Transporter Binds Nucleobases and Nucleosides Using Different Binding Modes

por Campagnaro, Gustavo D., Elati, Hamza A. A., Balaska, Sofia, Martin Abril, Maria Esther, Natto, Manal J., Hulpia, Fabian, Lee, Kelly, Sheiner, Lilach, Van Calenbergh, Serge, de Koning, Harry P.
Publicado 2022

Antiparasitic and Cytotoxic Activity of Bokkosin, A Novel Diterpene-Substituted Chromanyl Benzoquinone From Calliandra portoricensis

por Nvau, John B., Alenezi, Samya, Ungogo, Marzuq A., Alfayez, Ibrahim A. M., Natto, Manal J., Gray, Alexander I., Ferro, Valerie A., Watson, Dave G., de Koning, Harry P., Igoli, John O.
Publicado 2020

Nucleoside Transport and Nucleobase Uptake Null Mutants in Leishmania mexicana for the Routine Expression and Characterization of Purine and Pyrimidine Transporters

por Aldfer, Mustafa M., AlSiari, Tahani A., Elati, Hamza A. A., Natto, Manal J., Alfayez, Ibrahim A., Campagnaro, Gustavo D., Sani, Bashiru, Burchmore, Richard J. S., Diallinas, George, De Koning, Harry P.
Publicado 2022

Activity of Compounds from Temperate Propolis against Trypanosoma brucei and Leishmania mexicana

por Alotaibi, Adullah, Ebiloma, Godwin U., Williams, Roderick, Alfayez, Ibrahim A., Natto, Manal J., Alenezi, Sameah, Siheri, Weam, AlQarni, Malik, Igoli, John O., Fearnley, James, De Koning, Harry P., Watson, David G.
Publicado 2021

The Antiprotozoal Activity of Papua New Guinea Propolis and Its Triterpenes

por Alenezi, Samya S., Alenezi, Naif D., Ebiloma, Godwin U., Natto, Manal J., Ungogo, Marzuq A., Igoli, John O., Ferro, Valerie A., Gray, Alexander I., Fearnley, James, de Koning, Harry P., Watson, David G.
Publicado 2022

The Activity of Red Nigerian Propolis and Some of Its Components against Trypanosoma brucei and Trypanosoma congolense

por Alenezi, Samya S., Alenezi, Naif D., Ebiloma, Godwin U., Natto, Manal J., Ungogo, Marzuq A., Igoli, John O., Ferro, Valerie A., Gray, Alexander I., Fearnley, James, de Koning, Harry P., Watson, David G.
Publicado 2023

Cloning and Characterization of Trypanosoma congolense and T. vivax Nucleoside Transporters Reveal the Potential of P1-Type Carriers for the Discovery of Broad-Spectrum Nucleoside-...

por Ungogo, Marzuq A., Aldfer, Mustafa M., Natto, Manal J., Zhuang, Hainan, Chisholm, Robyn, Walsh, Katy, McGee, MarieClaire, Ilbeigi, Kayhan, Asseri, Jamal Ibrahim, Burchmore, Richard J. S., Caljon, Guy, Van Calenbergh, Serge, De Koning, Harry P.
Publicado 2023

Investigation of 5’-Norcarbocyclic Nucleoside Analogues as Antiprotozoal and Antibacterial Agents

por Khandazhinskaya, Anastasia L., Matyugina, Elena S., Solyev, Pavel N., Wilkinson, Maggie, Buckheit, Karen W., Buckheit, Robert W., Chernousova, Larisa N., Smirnova, Tatiana G., Andreevskaya, Sofya N., Alzahrani, Khalid J., Natto, Manal J., Kochetkov, Sergey N., de Koning, Harry P., Seley-Radtke, Katherine L.
Publicado 2019

Trypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of resistance to these drugs

por Munday, Jane C., Eze, Anthonius A., Baker, Nicola, Glover, Lucy, Clucas, Caroline, Aguinaga Andrés, David, Natto, Manal J., Teka, Ibrahim A., McDonald, Jennifer, Lee, Rebecca S., Graf, Fabrice E., Ludin, Philipp, Burchmore, Richard J. S., Turner, C. Michael R., Tait, Andy, MacLeod, Annette, Mäser, Pascal, Barrett, Michael P., Horn, David, De Koning, Harry P.
Publicado 2014