Challenges Related to Acquisition of Physiological Data for Physiologically Based Pharmacokinetic (PBPK) Models in Postpartum, Lactating Women and Breastfed Infants—A Contribution...

por Van Neste, Martje, Bogaerts, Annick, Nauwelaerts, Nina, Macente, Julia, Smits, Anne, Annaert, Pieter, Allegaert, Karel
Publicado 2023

Case Report: Bosentan and Sildenafil Exposure in Human Milk - A Contribution From the ConcePTION Project

por Nauwelaerts, Nina, Ceulemans, Michael, Deferm, Neel, Eerdekens, An, Lammens, Bart, Armoudjian, Yeghig, Van Calsteren, Kristel, Allegaert, Karel, de Vries, Loes, Annaert, Pieter, Smits, Anne
Publicado 2022

PBPK-based dose finding for sildenafil in pregnant women for antenatal treatment of congenital diaphragmatic hernia

por Macente, Julia, Nauwelaerts, Nina, Russo, Francesca M., Deprest, Jan, Allegaert, Karel, Lammens, Bart, Hernandes Bonan, Rodolfo, Turner, Jessica M., Kumar, Sailesh, Diniz, Andrea, Martins, Frederico S., Annaert, Pieter
Publicado 2023

Development of a Pig Mammary Epithelial Cell Culture Model as a Non-Clinical Tool for Studying Epithelial Barrier—A Contribution from the IMI-ConcePTION Project

por Bernardini, Chiara, La Mantia, Debora, Salaroli, Roberta, Zannoni, Augusta, Nauwelaerts, Nina, Deferm, Neel, Ventrella, Domenico, Bacci, Maria Laura, Sarli, Giuseppe, Bouisset-Leonard, Michele, Annaert, Pieter, Forni, Monica
Publicado 2021

Generic Workflow to Predict Medicine Concentrations in Human Milk Using Physiologically-Based Pharmacokinetic (PBPK) Modelling—A Contribution from the ConcePTION Project

por Nauwelaerts, Nina, Macente, Julia, Deferm, Neel, Bonan, Rodolfo Hernandes, Huang, Miao-Chan, Van Neste, Martje, Bibi, David, Badee, Justine, Martins, Frederico S., Smits, Anne, Allegaert, Karel, Bouillon, Thomas, Annaert, Pieter
Publicado 2023