Module-Based Polyketide Synthase Engineering for de Novo Polyketide Biosynthesis

por Nava, Alberto A., Roberts, Jacob, Haushalter, Robert W., Wang, Zilong, Keasling, Jay D.
Publicado 2023

Biosensor Guided Polyketide Synthases Engineering for Optimization of Domain Exchange Boundaries

por Englund, Elias, Schmidt, Matthias, Nava, Alberto A., Klass, Sarah, Keiser, Leah, Dan, Qingyun, Katz, Leonard, Yuzawa, Satoshi, Keasling, Jay D.
Publicado 2023

ClusterCAD 2.0: an updated computational platform for chimeric type I polyketide synthase and nonribosomal peptide synthetase design

por Tao, Xavier B, LaFrance, Sarah, Xing, Yifei, Nava, Alberto A, Martin, Hector Garcia, Keasling, Jay D, Backman, Tyler W H
Publicado 2022

Maximizing Heterologous Expression of Engineered Type I Polyketide Synthases: Investigating Codon Optimization Strategies

por Schmidt, Matthias, Lee, Namil, Zhan, Chunjun, Roberts, Jacob B., Nava, Alberto A., Keiser, Leah S., Vilchez, Aaron A., Chen, Yan, Petzold, Christopher J., Haushalter, Robert W., Blank, Lars M., Keasling, Jay D.
Publicado 2023

Expanding Extender Substrate Selection for Unnatural Polyketide Biosynthesis by Acyltransferase Domain Exchange within a Modular Polyketide Synthase

por Englund, Elias, Schmidt, Matthias, Nava, Alberto A., Lechner, Anna, Deng, Kai, Jocic, Renee, Lin, Yingxin, Roberts, Jacob, Benites, Veronica T., Kakumanu, Ramu, Gin, Jennifer W., Chen, Yan, Liu, Yuzhong, Petzold, Christopher J., Baidoo, Edward E. K., Northen, Trent R., Adams, Paul D., Katz, Leonard, Yuzawa, Satoshi, Keasling, Jay D.
Publicado 2023