Immunovirotherapy for Pediatric Solid Tumors: A Promising Treatment That is Becoming a Reality

por de la Nava, Daniel, Selvi, Kadir Mert, Alonso, Marta M.
Publicado 2022

THER-02. EVALUATION OF THE ONCOLYTIC VIRUS DELTA24-RGD AS AN ANTI-TUMOR AGENT IN PRECLINICAL MODELS OF LOCALIZED AND DISSEMINATED AT/RT

por Garcia-Moure, Marc, González-Huarriz, Marisol, de la Nava, Daniel, Marrodán, Lucía, Gomez-Manzano, Cande, Fueyo, Juan, Patiño-García, Ana, Alonso, Marta M
Publicado 2020

DIPG-10. DELTA-24-RGDOX PROMOTES ANTITUMOR IMMUNE RESPONSE IN DMG MODELS

por Laspidea, Virginia, Ausejo-Mauleon, Iker, de la Nava, Daniel, Nuin, Sara, Hernandez-Osuna, Reyes, Marco-Sanz, Javier, Palacios-Alonso, Daniel, Gomez-Manzano, Candelaria, Fueyo, Juan, Alonso, Marta
Publicado 2023

IMMU-06. DELTA-24-RGD EXPRESSING POSITIVE IMMUNE MODULATORS SHOW ANTI-DIPG EFFECT AND INCREASE TUMOR IMMUNE INFILTRATION

por Laspidea, Virginia, Gupta, Sumit, Puigdelloses, Montserrat, Labiano, Sara, Ausejo-Mauleon, Iker, de la Nava, Daniel, Becher, Oren J, Gumin, Joy, Fueyo, Juan, Gomez-Manzano, Candelaria, Alonso, Marta M
Publicado 2021

DIPG-04. TUMOR CELL-INTRINSIC TIM-3 PROMOTES DIFFUSE INTRINSIC PONTINE GLIOMA TUMORIGENESIS

por Ausejo-Mauleon, Iker, Laspidea, Virginia, de la Nava, Daniel, Nuin, Sara, Palacios-Alonso, Daniel, Marco-Sanz, Javier, Becher, Oren, Jiang, Li, Filbon, Mariella G, Pastor, Fernando, Alonso, Marta M
Publicado 2023

IMMU-08. MICROENVIRONMENT MODULATION BY TIM-3 BLOCKADE IMPROVES THE OUTCOME OF PRECLINICAL DIPG MODELS

por Ausejo-Mauleon, Iker, Labiano, Sara, Laspidea, Virginia, Garcia-Moure, Marc, de la Nava, Daniel, Puigdelloses, Montserrat, Becher, Oren J, Jiang, Li, Filbin, Mariella G, Pastor, Fernando, Alonso, Marta M
Publicado 2021

HGG-15. THE IMIPRIDONE ONC201 IN COMBINATION WITH THE ONCOLYTIC ADENOVIRUS DELTA-24-RGD HAS A SYNERGISTIC EFFECT IN PRECLINICAL MODELS OF PHGGS AND DMGS

por de la Nava, Daniel, Ausejo-Mauleon, Iker, Laspidea, Virginia, Marrodán, Lucía, Zalacain, Marta, Herrador-Cañete, Guillermo, Nazarian, Javad, Mueller, Sabine, Allen, Joshua E, Fueyo, Juan, Gomez-Manzano, Candelaria, Gupta, Sumit, Patiño, Ana, Alonso, Marta M
Publicado 2021

Somatic Copy Number Alteration in Circulating Tumor DNA for Monitoring of Pediatric Patients with Cancer

por Ruas, Juliana Silveira, Silva, Felipe Luz Torres, Euzébio, Mayara Ferreira, Biazon, Tássia Oliveira, Daiggi, Camila Maia Martin, Nava, Daniel, Franco, Mayra Troiani, Cardinalli, Izilda Aparecida, Cassone, Alejandro Enzo, Pereira, Luiz Henrique, Seidinger, Ana Luiza, Maschietto, Mariana, Jotta, Patricia Yoshioka
Publicado 2023

Local Treatment of a Pediatric Osteosarcoma Model with a 4-1BBL Armed Oncolytic Adenovirus Results in an Antitumor Effect and Leads to Immune Memory

por Martinez-Velez, Naiara, Laspidea, Virginia, Zalacain, Marta, Labiano, Sara, García-Moure, Marc, Puigdelloses, Montse, Marrodan, Lucía, Gonzalez-Huarriz, Marisol, Herrador, Guillermo, de la Nava, Daniel, Ausejo-Mauleon, Iker, Fueyo, Juan, Gomez-Manzano, Candelaria, Patiño-García, Ana, Alonso, Marta M.
Publicado 2022

Epigenetic Deregulation of the Histone Methyltransferase KMT5B Contributes to Malignant Transformation in Glioblastoma

por López, Virginia, Tejedor, Juan Ramón, Carella, Antonella, García, María G., Santamarina-Ojeda, Pablo, Pérez, Raúl F., Mangas, Cristina, Urdinguio, Rocío G., Aranburu, Aitziber, de la Nava, Daniel, Corte-Torres, María D., Astudillo, Aurora, Mollejo, Manuela, Meléndez, Bárbara, Fernández, Agustín F., Fraga, Mario F.
Publicado 2021

CD137 and PD-L1 targeting with immunovirotherapy induces a potent and durable antitumor immune response in glioblastoma models

por Puigdelloses, Montserrat, Garcia-Moure, Marc, Labiano, Sara, Laspidea, Virginia, Gonzalez-Huarriz, Marisol, Zalacain, Marta, Marrodan, Lucia, Martinez-Velez, Naiara, De la Nava, Daniel, Ausejo, Iker, Hervás-Stubbs, Sandra, Herrador, Guillermo, Chen, ZhiHong, Hambardzumyan, Dolores, Patino Garcia, Ana, Jiang, Hong, Gomez-Manzano, Candelaria, Fueyo, Juan, Gállego Pérez-Larraya, Jaime, Alonso, Marta
Publicado 2021

Galectin-3 inhibition boosts the therapeutic efficacy of Semliki Forest virus in pediatric osteosarcoma

por Herrador-Cañete, Guillermo, Zalacain, Marta, Labiano, Sara, Laspidea, Virginia, Puigdelloses, Montserrat, Marrodan, Lucía, Garcia-Moure, Marc, Gonzalez-Huarriz, Marisol, Marco-Sanz, Javier, Ausejo-Mauleon, Iker, de la Nava, Daniel, Hernández-Osuna, Reyes, Martínez-García, Javier, Silva-Pilipich, Noelia, Gurucega, Elisabeth, Patiño-García, Ana, Hernández-Alcoceba, Rubén, Smerdou, Cristian, Alonso, Marta M.
Publicado 2022

Exploiting 4-1BB immune checkpoint to enhance the efficacy of oncolytic virotherapy for diffuse intrinsic pontine gliomas

por Laspidea, Virginia, Puigdelloses, Montserrat, Labiano, Sara, Marrodán, Lucía, Garcia-Moure, Marc, Zalacain, Marta, Gonzalez-Huarriz, Marisol, Martínez-Vélez, Naiara, Ausejo-Mauleon, Iker, de la Nava, Daniel, Herrador-Cañete, Guillermo, Marco-Sanz, Javier, Guruceaga, Elisabeth, de Andrea, Carlos E., Villalba, María, Becher, Oren, Squatrito, Massimo, Matía, Verónica, Gállego Pérez-Larraya, Jaime, Patiño-García, Ana, Gupta, Sumit, Gomez-Manzano, Candelaria, Fueyo, Juan, Alonso, Marta M.
Publicado 2022

TIM-3 blockade in diffuse intrinsic pontine glioma models promotes tumor regression and antitumor immune memory

por Ausejo-Mauleon, Iker, Labiano, Sara, de la Nava, Daniel, Laspidea, Virginia, Zalacain, Marta, Marrodán, Lucía, García-Moure, Marc, González-Huarriz, Marisol, Hervás-Corpión, Irati, Dhandapani, Laasya, Vicent, Silvestre, Collantes, Maria, Peñuelas, Iván, Becher, Oren J., Filbin, Mariella G., Jiang, Li, Labelle, Jenna, de Biagi-Junior, Carlos A.O., Nazarian, Javad, Laternser, Sandra, Phoenix, Timothy N., van der Lugt, Jasper, Kranendonk, Mariette, Hoogendijk, Raoull, Mueller, Sabine, De Andrea, Carlos, Anderson, Ana C., Guruceaga, Elizabeth, Koschmann, Carl, Yadav, Viveka Nand, Gállego Pérez-Larraya, Jaime, Patiño-García, Ana, Pastor, Fernando, Alonso, Marta M.
Publicado 2023

Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways

por Venneti, Sriram, Kawakibi, Abed Rahman, Ji, Sunjong, Waszak, Sebastian M., Sweha, Stefan R., Mota, Mateus, Pun, Matthew, Deogharkar, Akash, Chung, Chan, Tarapore, Rohinton S., Ramage, Samuel, Chi, Andrew, Wen, Patrick Y., Arrillaga-Romany, Isabel, Batchelor, Tracy T., Butowski, Nicholas A., Sumrall, Ashley, Shonka, Nicole, Harrison, Rebecca A., de Groot, John, Mehta, Minesh, Hall, Matthew D., Daghistani, Doured, Cloughesy, Timothy F., Ellingson, Benjamin M., Beccaria, Kevin, Varlet, Pascale, Kim, Michelle M., Umemura, Yoshie, Garton, Hugh, Franson, Andrea, Schwartz, Jonathan, Jain, Rajan, Kachman, Maureen, Baum, Heidi, Burant, Charles F., Mottl, Sophie L., Cartaxo, Rodrigo T., John, Vishal, Messinger, Dana, Qin, Tingting, Peterson, Erik, Sajjakulnukit, Peter, Ravi, Karthik, Waugh, Alyssa, Walling, Dustin, Ding, Yujie, Xia, Ziyun, Schwendeman, Anna, Hawes, Debra, Yang, Fusheng, Judkins, Alexander R., Wahl, Daniel, Lyssiotis, Costas A., de la Nava, Daniel, Alonso, Marta M., Eze, Augustine, Spitzer, Jasper, Schmidt, Susanne V., Duchatel, Ryan J., Dun, Matthew D., Cain, Jason E., Jiang, Li, Stopka, Sylwia A., Baquer, Gerard, Regan, Michael S., Filbin, Mariella G., Agar, Nathalie Y.R., Zhao, Lili, Kumar-Sinha, Chandan, Mody, Rajen, Chinnaiyan, Arul, Kurokawa, Ryo, Pratt, Drew, Yadav, Viveka N., Grill, Jacques, Kline, Cassie, Mueller, Sabine, Resnick, Adam, Nazarian, Javad, Allen, Joshua E., Odia, Yazmin, Gardner, Sharon L., Koschmann, Carl
Publicado 2023