Screening for GPCR Ligands Using Surface Plasmon Resonance

por Navratilova, Iva, Besnard, Jérémy, Hopkins, Andrew L.
Publicado 2011

Substrate and product analogues as human O-GlcNAc transferase inhibitors

por Dorfmueller, Helge C., Borodkin, Vladimir S., Blair, David E., Pathak, Shalini, Navratilova, Iva, van Aalten, Daan M. F.
Publicado 2010

Structure of a bacterial putative acetyltransferase defines the fold of the human O-GlcNAcase C-terminal domain

por Rao, Francesco V., Schüttelkopf, Alexander W., Dorfmueller, Helge C., Ferenbach, Andrew T., Navratilova, Iva, van Aalten, Daan M. F.
Publicado 2013

ATP and MO25α Regulate the Conformational State of the STRADα Pseudokinase and Activation of the LKB1 Tumour Suppressor

por Zeqiraj, Elton, Filippi, Beatrice Maria, Goldie, Simon, Navratilova, Iva, Boudeau, Jérôme, Deak, Maria, Alessi, Dario R., van Aalten, Daan M. F.
Publicado 2009

O-GlcNAc transferase invokes nucleotide sugar pyrophosphate participation in catalysis

por Schimpl, Marianne, Zheng, Xiaowei, Borodkin, Vladimir S., Blair, David E., Ferenbach, Andrew T., Schüttelkopf, Alexander W., Navratilova, Iva, Aristotelous, Tonia, Albarbarawi, Osama, Robinson, David A., Macnaughtan, Megan A., van Aalten, Daan M.F.
Publicado 2012

A Novel Allosteric Inhibitor of the Uridine Diphosphate N-Acetylglucosamine Pyrophosphorylase from Trypanosoma brucei

por Urbaniak, Michael D., Collie, Iain T., Fang, Wenxia, Aristotelous, Tonia, Eskilsson, Susanne, Raimi, Olawale G., Harrison, Justin, Navratilova, Iva Hopkins, Frearson, Julie A., van Aalten, Daan M. F., Ferguson, Michael A. J.
Publicado 2013

Identification of Inhibitors of the Schistosoma mansoni VKR2 Kinase Domain

por Mathavan, Indran, Liu, Lawrence J., Robinson, Sean W., El-Sakkary, Nelly, Elatico, Adam Jo J., Gomez, Darwin, Nellas, Ricky, Owens, Raymond J., Zuercher, William, Navratilova, Iva, Caffrey, Conor R., Beis, Konstantinos
Publicado 2022

GacA is essential for Group A S treptococcus and defines a new class of monomeric dTDP‐4‐dehydrorhamnose reductases (RmlD)

por van der Beek, Samantha L., Le Breton, Yoann, Ferenbach, Andrew T., Chapman, Robert N., van Aalten, Daan M. F., Navratilova, Iva, Boons, Geert‐Jan, McIver, Kevin S., van Sorge, Nina M., Dorfmueller, Helge C.
Publicado 2015

Discovery and Characterization of Selective and Ligand-Efficient DYRK Inhibitors

por Henderson, Scott H., Sorrell, Fiona, Bennett, James, Fedorov, Oleg, Hanley, Marcus T., Godoi, Paulo H., Ruela de Sousa, Roberta, Robinson, Sean, Ashall-Kelly, Alexander, Hopkins Navratilova, Iva, Walter, Daryl S., Elkins, Jonathan M., Ward, Simon E.
Publicado 2021

Discovery of β2 Adrenergic Receptor Ligands Using Biosensor Fragment Screening of Tagged Wild-Type Receptor

por Aristotelous, Tonia, Ahn, Seungkirl, Shukla, Arun K., Gawron, Sylwia, Sassano, Maria F., Kahsai, Alem W., Wingler, Laura M., Zhu, Xiao, Tripathi-Shukla, Prachi, Huang, Xi-Ping, Riley, Jennifer, Besnard, Jérémy, Read, Kevin D., Roth, Bryan L., Gilbert, Ian H., Hopkins, Andrew L., Lefkowitz, Robert J., Navratilova, Iva
Publicado 2013

Fragment-derived inhibitors of human N-myristoyltransferase block capsid assembly and replication of the common cold virus

por Mousnier, Aurélie, Bell, Andrew S., Swieboda, Dawid P., Morales-Sanfrutos, Julia, Pérez-Dorado, Inmaculada, Brannigan, James A., Newman, Joseph, Ritzefeld, Markus, Hutton, Jennie A., Guedán, Anabel, Asfor, Amin A., Robinson, Sean W., Hopkins-Navratilova, Iva, Wilkinson, Anthony J., Johnston, Sebastian L., Leatherbarrow, Robin J., Tuthill, Tobias J., Solari, Roberto, Tate, Edward W.
Publicado 2018