Autophagy: New Insights into Its Roles in Cancer Progression and Drug Resistance

por Nawrocki, Steffan T., Wang, Wei, Carew, Jennifer S.
Publicado 2020

Autophagy as a target for cancer therapy: new developments

por Carew, Jennifer S, Kelly, Kevin R, Nawrocki, Steffan T
Publicado 2012

Therapeutic Targeting of Autophagy for Renal Cell Carcinoma Therapy

por Jones, Trace M., Carew, Jennifer S., Nawrocki, Steffan T.
Publicado 2020

Targeting autophagy: a novel anticancer strategy with therapeutic implications for imatinib resistance

por Carew, Jennifer S, Nawrocki, Steffan T, Giles, Francis J, Cleveland, John L
Publicado 2008

Targeting NEDDylation as a Novel Approach to Improve the Treatment of Head and Neck Cancer

por Jones, Trace M., Carew, Jennifer S., Bauman, Julie E., Nawrocki, Steffan T.
Publicado 2021

Moving beyond hydroxychloroquine: the novel lysosomal autophagy inhibitor ROC-325 shows significant potential in preclinical studies

por Jones, Trace M., Espitia, Claudia, Wang, Wei, Nawrocki, Steffan T., Carew, Jennifer S.
Publicado 2019

Oncolytic Viruses for Multiple Myeloma Therapy

por Calton, Christine M., Kelly, Kevin R., Anwer, Faiz, Carew, Jennifer S., Nawrocki, Steffan T.
Publicado 2018

Targeting JAK/STAT Signaling Antagonizes Resistance to Oncolytic Reovirus Therapy Driven by Prior Infection with HTLV-1 in Models of T-Cell Lymphoma

por Islam, Shariful, Espitia, Claudia M., Persky, Daniel O., Carew, Jennifer S., Nawrocki, Steffan T.
Publicado 2021

The combination of intravenous Reolysin and gemcitabine induces reovirus replication and endoplasmic reticular stress in a patient with KRAS-activated pancreatic cancer

por Mahalingam, Devalingam, Patel, Sukeshi, Nuovo, Gerard, Gill, George, Selvaggi, Giovanni, Coffey, Matt, Nawrocki, Steffan T.
Publicado 2015

Oncolytic reovirus inhibits angiogenesis through induction of CXCL10/IP-10 and abrogation of HIF activity in soft tissue sarcomas

por Carew, Jennifer S., Espitia, Claudia M., Zhao, Weiguo, Mita, Monica M., Mita, Alain C., Nawrocki, Steffan T.
Publicado 2017

Targeted CUL4A inhibition synergizes with cisplatin to yield long-term survival in models of head and neck squamous cell carcinoma through a DDB2-mediated mechanism

por Jones, Trace M., Espitia, Claudia M., Ooi, Aikseng, Bauman, Julie E., Carew, Jennifer S., Nawrocki, Steffan T.
Publicado 2022

Vorinostat and hydroxychloroquine improve immunity and inhibit autophagy in metastatic colorectal cancer

por Patel, Sukeshi, Hurez, Vincent, Nawrocki, Steffan T., Goros, Martin, Michalek, Joel, Sarantopoulos, John, Curiel, Tyler, Mahalingam, Devalingam
Publicado 2016

Inhibiting signal transducer and activator of transcription-3 increases response to gemcitabine and delays progression of pancreatic cancer

por Venkatasubbarao, Kolaparthi, Peterson, Lindsay, Zhao, Shujie, Hill, Ping, Cao, Lin, Zhou, Qing, Nawrocki, Steffan T, Freeman, James W
Publicado 2013

The novel Aurora A kinase inhibitor MLN8237 is active in resistant chronic myeloid leukaemia and significantly increases the efficacy of nilotinib

por Kelly, Kevin R, Ecsedy, Jeffrey, Medina, Ernest, Mahalingam, Devalingam, Padmanabhan, Swaminathan, Nawrocki, Steffan T, Giles, Francis J, Carew, Jennifer S
Publicado 2011

Junctional adhesion molecule-A is overexpressed in advanced multiple myeloma and determines response to oncolytic reovirus

por Kelly, Kevin R., Espitia, Claudia M., Zhao, Weiguo, Wendlandt, Erik, Tricot, Guido, Zhan, Fenghuang, Carew, Jennifer S., Nawrocki, Steffan T.
Publicado 2015

Heightened JNK Activation and Reduced XIAP Levels Promote TRAIL and Sunitinib-Mediated Apoptosis in Colon Cancer Models

por Mahalingam, Devalingam, Carew, Jennifer S., Espitia, Claudia M., Cool, Robbert H., Giles, Francis J., de Jong, Steven, Nawrocki, Steffan T.
Publicado 2019

Targeting NEDDylation is a Novel Strategy to Attenuate Cisplatin-induced Nephrotoxicity

por Jones, Trace M., Espitia, Claudia M., Chipollini, Juan, Lee, Benjamin R., Wertheim, Jason A., Carew, Jennifer S., Nawrocki, Steffan T.
Publicado 2023

Oncolytic reovirus sensitizes multiple myeloma cells to anti-PD-L1 therapy

por Kelly, Kevin R., Espitia, Claudia M., Zhao, Weiguo, Wu, Kaijin, Visconte, Valeria, Anwer, Faiz, Calton, Christine M., Carew, Jennifer S., Nawrocki, Steffan T.
Publicado 2017

ELR510444 Inhibits Tumor Growth and Angiogenesis by Abrogating HIF Activity and Disrupting Microtubules in Renal Cell Carcinoma

por Carew, Jennifer S., Esquivel, Juan A., Espitia, Claudia M., Schultes, Christoph M., Mülbaier, Marcel, Lewis, Joe D., Janssen, Bernd, Giles, Francis J., Nawrocki, Steffan T.
Publicado 2012

ABCG2 Overexpression Contributes to Pevonedistat Resistance

por Kathawala, Rishil J., Espitia, Claudia M., Jones, Trace M., Islam, Shariful, Gupta, Pranav, Zhang, Yun-Kai, Chen, Zhe-Sheng, Carew, Jennifer S., Nawrocki, Steffan T.
Publicado 2020