The role of non-hematopoietic stromal cells in the persistence of inflammation

por Barone, Francesca, Nayar, Saba, Buckley, Chris D.
Publicado 2013

Tertiary Lymphoid Structures: Autoimmunity Goes Local

por Pipi, Elena, Nayar, Saba, Gardner, David H., Colafrancesco, Serena, Smith, Charlotte, Barone, Francesca
Publicado 2018

Stromal Fibroblasts in Tertiary Lymphoid Structures: A Novel Target in Chronic Inflammation

por Barone, Francesca, Gardner, David H., Nayar, Saba, Steinthal, Nathalie, Buckley, Christopher D., Luther, Sanjiv A.
Publicado 2016

Adipogenic Differentiation of Mesenchymal Stem Cells Alters Their Immunomodulatory Properties in a Tissue‐Specific Manner

por Munir, Hafsa, Ward, Lewis S. C., Sheriff, Lozan, Kemble, Samuel, Nayar, Saba, Barone, Francesca, Nash, Gerard B., McGettrick, Helen M.
Publicado 2017

The expression of mouse CLEC‐2 on leucocyte subsets varies according to their anatomical location and inflammatory state

por Lowe, Kate L., Navarro‐Núñez, Leyre, Bénézech, Cécile, Nayar, Saba, Kingston, Bethany L., Nieswandt, Bernhard, Barone, Francesca, Watson, Steve P., Buckley, Christopher D., Desanti, Guillaume E.
Publicado 2015

Sjögren’s and non-Sjögren’s sicca share a similar symptom burden but with a distinct symptom-associated proteomic signature

por Pucino, Valentina, Turner, Jason D, Nayar, Saba, Kollert, Florian, Rauz, Saaeha, Richards, Andrea, Higham, Jon, Poveda-Gallego, Ana, Bowman, Simon J, Barone, Francesca, Fisher, Benjamin A
Publicado 2022

Salmonella infection induces the reorganization of follicular dendritic cell networks concomitant with the failure to generate germinal centers

por Marcial-Juárez, Edith, Pérez-Toledo, Marisol, Nayar, Saba, Pipi, Elena, Alshayea, Areej, Persaud, Ruby, Jossi, Sian E., Lamerton, Rachel, Barone, Francesca, Henderson, Ian R., Cunningham, Adam F.
Publicado 2023

Cenerimod, a selective S1P(1) receptor modulator, improves organ-specific disease outcomes in animal models of Sjögren’s syndrome

por Gerossier, Estelle, Nayar, Saba, Froidevaux, Sylvie, Smith, Charlotte G., Runser, Celine, Iannizzotto, Valentina, Vezzali, Enrico, Pierlot, Gabin, Mentzel, Ulrich, Murphy, Mark J., Martinic, Marianne M., Barone, Francesca
Publicado 2021

Immunoglobulin light chain allelic inclusion in systemic lupus erythematosus

por Fraser, Louise D., Zhao, Yuan, Lutalo, Pamela M. K., D'Cruz, David P., Cason, John, Silva, Joselli S., Dunn‐Walters, Deborah K., Nayar, Saba, Cope, Andrew P., Spencer, Jo
Publicado 2015

Bimodal Expansion of the Lymphatic Vessels Is Regulated by the Sequential Expression of IL-7 and Lymphotoxin α(1)β(2) in Newly Formed Tertiary Lymphoid Structures

por Nayar, Saba, Campos, Joana, Chung, Ming May, Navarro-Núñez, Leyre, Chachlani, Menka, Steinthal, Nathalie, Gardner, David H., Rankin, Philip, Cloake, Thomas, Caamaño, Jorge H., McGettrick, Helen M., Watson, Steve P., Luther, Sanjiv, Buckley, Christopher D., Barone, Francesca
Publicado 2016

Autophagy occurs in lymphocytes infiltrating Sjögren’s syndrome minor salivary glands and correlates with histological severity of salivary gland lesions

por Colafrancesco, Serena, Vomero, Marta, Iannizzotto, Valentina, Minniti, Antonina, Barbati, Cristiana, Arienzo, Francesca, Mastromanno, Linda, Colasanti, Tania, Izzo, Raffaella, Nayar, Saba, Pipi, Elena, Cerbelli, Bruna, Giordano, Carla, Ciccia, Francesco, Conti, Fabrizio, Valesini, Guido, Barone, Francesca, Priori, Roberta, Alessandri, Cristiano
Publicado 2020

KDM6B drives epigenetic reprogramming associated with lymphoid stromal cell early commitment and immune properties

por Sylvestre, Marvin, Barbier, Nicolas, Sibut, Vonick, Nayar, Saba, Monvoisin, Céline, Leonard, Simon, Saint-Vanne, Julien, Martin, Ansie, Guirriec, Marion, Latour, Maëlle, Jouan, Florence, Baulande, Sylvain, Bohec, Mylène, Verdière, Léa, Mechta-Grigoriou, Fatima, Mourcin, Frédéric, Bertheuil, Nicolas, Barone, Francesca, Tarte, Karin, Roulois, David
Publicado 2023

Immunofibroblasts are pivotal drivers of tertiary lymphoid structure formation and local pathology

por Nayar, Saba, Campos, Joana, Smith, Charlotte G., Iannizzotto, Valentina, Gardner, David H., Mourcin, Frédéric, Roulois, David, Turner, Jason, Sylvestre, Marvin, Asam, Saba, Glaysher, Bridget, Bowman, Simon J., Fearon, Douglas T., Filer, Andrew, Tarte, Karin, Luther, Sanjiv A., Fisher, Benjamin A., Buckley, Christopher D., Coles, Mark C., Barone, Francesca
Publicado 2019

Phosphatidylinositol 3-kinase delta pathway: a novel therapeutic target for Sjögren’s syndrome

por Nayar, Saba, Campos, Joana, Smith, Charlotte G, Iannizzotto, Valentina, Gardner, David H, Colafrancesco, Serena, Pipi, Elena, Kollert, Florian, Hunter, Kelly J, Brewer, Charlotte, Buckley, Christopher Dominic, Bowman, Simon J, Priori, Roberta, Valesini, Guido, Juarez, Maria, Fahy, William A, Fisher, Benjamin A, Payne, Andrew, Allen, Rodger A, Barone, Francesca
Publicado 2019

Immunofibroblasts regulate LTα3 expression in tertiary lymphoid structures in a pathway dependent on ICOS/ICOSL interaction

por Nayar, Saba, Pontarini, Elena, Campos, Joana, Berardicurti, Onorina, Smith, Charlotte G., Asam, Saba, Gardner, David H., Colafrancesco, Serena, Lucchesi, Davide, Coleby, Rachel, Chung, Ming-May, Iannizzotto, Valentina, Hunter, Kelly, Bowman, Simon J., Carlesso, Gianluca, Herbst, Ronald, McGettrick, Helen M., Browning, Jeff, Buckley, Christopher D., Fisher, Benjamin A., Bombardieri, Michele, Barone, Francesca
Publicado 2022

Tissue-resident, extravascular Ly6c(−) monocytes are critical for inflammation in the synovium

por Montgomery, Anna B., Chen, Shang Yang, Wang, Yidan, Gadhvi, Gaurav, Mayr, Maximilian G., Cuda, Carla M., Dominguez, Salina, Makinde, Hadijat-Kubura Moradeke, Gurra, Miranda G., Misharin, Alexander V., Mandelin, Arthur M., Ruderman, Eric M., Thakrar, Anjali, Brar, Simran, Carns, Mary, Aren, Kathleen, Akbarpour, Mahzad, Filer, Andrew, Nayar, Saba, Teososio, Ana, Major, Triin, Bharat, Ankit, Budinger, G.R. Scott, Winter, Deborah R., Perlman, Harris
Publicado 2023

Homeostatic regulation of T cell trafficking by a B cell derived peptide is impaired in autoimmune and chronic inflammatory disease

por Chimen, Myriam, McGettrick, Helen M., Apta, Bonita, Kuravi, Sahithi J., Yates, Clara M., Kennedy, Amy, Odedra, Arjun, Alassiri, Mohammed, Harrison, Matthew, Martin, Ashley, Barone, Francesca, Nayar, Saba, Hitchcock, Jessica R., Cunningham, Adam F., Raza, Karim, Filer, Andrew, Copland, David A., Dick, Andrew D., Robinson, Joseph, Kalia, Neena, Walker, Lucy S. K., Buckley, Christopher D., Nash, Gerard B., Narendran, Parth, Rainger, G. Ed.
Publicado 2015

Inflammation-induced formation of fat-associated lymphoid clusters

por Bénézech, Cécile, Luu, Nguyet-Thin, Walker, Jennifer A., Kruglov, Andrei A., Loo, Yunhua, Nakamura, Kyoko, Zhang, Yang, Nayar, Saba, Jones, Lucy H., Flores-Langarica, Adriana, McIntosh, Alistair, Marshall, Jennifer, Barone, Francesca, Besra, Gurdyal, Miles, Katherine, Allen, Judith E., Gray, Mohini, Kollias, George, Cunningham, Adam F., Withers, David R., Toellner, Kai Michael, Jones, Nick D., Veldhoen, Marc, Nedospasov, Sergei A., McKenzie, Andrew N.J., Caamaño, Jorge H.
Publicado 2015

Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes

por Zhang, Fan, Jonsson, Anna Helena, Nathan, Aparna, Millard, Nghia, Curtis, Michelle, Xiao, Qian, Gutierrez-Arcelus, Maria, Apruzzese, William, Watts, Gerald F. M., Weisenfeld, Dana, Nayar, Saba, Rangel-Moreno, Javier, Meednu, Nida, Marks, Kathryne E., Mantel, Ian, Kang, Joyce B., Rumker, Laurie, Mears, Joseph, Slowikowski, Kamil, Weinand, Kathryn, Orange, Dana E., Geraldino-Pardilla, Laura, Deane, Kevin D., Tabechian, Darren, Ceponis, Arnoldas, Firestein, Gary S., Maybury, Mark, Sahbudin, Ilfita, Ben-Artzi, Ami, Mandelin, Arthur M., Nerviani, Alessandra, Lewis, Myles J., Rivellese, Felice, Pitzalis, Costantino, Hughes, Laura B., Horowitz, Diane, DiCarlo, Edward, Gravallese, Ellen M., Boyce, Brendan F., Moreland, Larry W., Goodman, Susan M., Perlman, Harris, Holers, V. Michael, Liao, Katherine P., Filer, Andrew, Bykerk, Vivian P., Wei, Kevin, Rao, Deepak A., Donlin, Laura T., Anolik, Jennifer H., Brenner, Michael B., Raychaudhuri, Soumya
Publicado 2023