Structural model of the open–closed–inactivated cycle of prokaryotic voltage-gated sodium channels

por Bagnéris, Claire, Naylor, Claire E., McCusker, Emily C., Wallace, B.A.
Publicado 2015

Structural Insights into Clostridium perfringens Delta Toxin Pore Formation

por Huyet, Jessica, Naylor, Claire E., Savva, Christos G., Gibert, Maryse, Popoff, Michel R., Basak, Ajit K.
Publicado 2013

The complete structure of an activated open sodium channel

por Sula, Altin, Booker, Jennifer, Ng, Leo C. T., Naylor, Claire E., DeCaen, Paul G., Wallace, B. A.
Publicado 2017

Cryo-EM structure of lysenin pore elucidates membrane insertion by an aerolysin family protein

por Bokori-Brown, Monika, Martin, Thomas G., Naylor, Claire E., Basak, Ajit K., Titball, Richard W., Savva, Christos G.
Publicado 2016

Molecular basis of ion permeability in a voltage‐gated sodium channel

por Naylor, Claire E, Bagnéris, Claire, DeCaen, Paul G, Sula, Altin, Scaglione, Antonella, Clapham, David E, Wallace, BA
Publicado 2016

A novel high-throughput screen for identifying lipids that stabilise membrane proteins in detergent based solution

por Cecchetti, Cristina, Strauss, Jannik, Stohrer, Claudia, Naylor, Claire, Pryor, Edward, Hobbs, Jeanette, Tanley, Simon, Goldman, Adrian, Byrne, Bernadette
Publicado 2021

Structure of a bacterial voltage-gated sodium channel pore reveals mechanisms of opening and closing

por McCusker, Emily C., Bagnéris, Claire, Naylor, Claire E., Cole, Ambrose R., D'Avanzo, Nazzareno, Nichols, Colin G., Wallace, B.A.
Publicado 2012

Role of the C-terminal domain in the structure and function of tetrameric sodium channels

por Bagnéris, Claire, DeCaen, Paul G., Hall, Benjamin A., Naylor, Claire E., Clapham, David E., Kay, Christopher W. M., Wallace, B. A.
Publicado 2013

Identification of a Key Residue for Oligomerisation and Pore-Formation of Clostridium perfringens NetB

por Fernandes da Costa, Sérgio P., Savva, Christos G., Bokori-Brown, Monika, Naylor, Claire E., Moss, David S., Basak, Ajit K., Titball, Richard W.
Publicado 2014

The pore structure of Clostridium perfringens epsilon toxin

por Savva, Christos G., Clark, Alice R., Naylor, Claire E., Popoff, Michel R., Moss, David S., Basak, Ajit K., Titball, Richard W., Bokori-Brown, Monika
Publicado 2019

Molecular Architecture and Functional Analysis of NetB, a Pore-forming Toxin from Clostridium perfringens

por Savva, Christos G., Fernandes da Costa, Sérgio P., Bokori-Brown, Monika, Naylor, Claire E., Cole, Ambrose R., Moss, David S., Titball, Richard W., Basak, Ajit K.
Publicado 2013

Clostridium perfringens epsilon toxin H149A mutant as a platform for receptor binding studies

por Bokori-Brown, Monika, Kokkinidou, Maria C, Savva, Christos G, Fernandes da Costa, Sérgio, Naylor, Claire E, Cole, Ambrose R, Moss, David S, Basak, Ajit K, Titball, Richard W
Publicado 2013

Ultra-high resolution X-ray structure of orthorhombic bovine pancreatic Ribonuclease A at 100K

por Lisgarten, David R., Palmer, Rex A., Cooper, Jon B., Naylor, Claire E., Talbert, Rosemary C., Howlin, Brendan J., Lisgarten, John N., Konc, Janez, Najmudin, Shabir, Lobley, Carina M. C.
Publicado 2023

Clostridium perfringens epsilon toxin mutant Y30A-Y196A as a recombinant vaccine candidate against enterotoxemia

por Bokori-Brown, Monika, Hall, Charlotte A., Vance, Charlotte, Fernandes da Costa, Sérgio P., Savva, Christos G., Naylor, Claire E., Cole, Ambrose R., Basak, Ajit K., Moss, David S., Titball, Richard W.
Publicado 2014

Discovery of super soft-drug modulators of sphingosine-1-phosphate receptor 1

por Bell, Mark, Foley, David, Naylor, Claire, Robinson, Colin, Riley, Jennifer, Epemolu, Ola, Scullion, Paul, Shishikura, Yoko, Katz, Elad, McLean, W.H. Irwin, Wyatt, Paul, Read, Kevin D., Woodland, Andrew
Publicado 2018

Ultra-high resolution X-ray structures of two forms of human recombinant insulin at 100 K

por Lisgarten, David R., Palmer, Rex A., Lobley, Carina M. C., Naylor, Claire E., Chowdhry, Babur Z., Al-Kurdi, Zakieh I., Badwan, Adnan A., Howlin, Brendan J., Gibbons, Nicholas C. J., Saldanha, José W., Lisgarten, John N., Basak, Ajit K.
Publicado 2017

Discovery of Soft-Drug Topical Tool Modulators of Sphingosine-1-phosphate Receptor 1 (S1PR1)

por Bell, Mark, Foley, David, Naylor, Claire, Wood, Gavin, Robinson, Colin, Riley, Jennifer, Epemolu, Ola, Ellis, Lucy, Scullion, Paul, Shishikura, Yoko, Osuna-Cabello, Maria, Ferguson, Liam, Pinto, Erika, Fletcher, Daniel, Katz, Elad, McLean, W. H. Irwin, Wyatt, Paul, Read, Kevin D, Woodland, Andrew
Publicado 2019

Identification and Optimization of a Series of 8-Hydroxy Naphthyridines with Potent In Vitro Antileishmanial Activity: Initial SAR and Assessment of In Vivo Activity

por Thomas, Michael G., De Rycker, Manu, Wall, Richard J., Spinks, Daniel, Epemolu, Ola, Manthri, Sujatha, Norval, Suzanne, Osuna-Cabello, Maria, Patterson, Stephen, Riley, Jennifer, Simeons, Frederick R. C., Stojanovski, Laste, Thomas, John, Thompson, Stephen, Naylor, Claire, Fiandor, Jose M., Wyatt, Paul G., Marco, Maria, Wyllie, Susan, Read, Kevin D., Miles, Timothy J., Gilbert, Ian H.
Publicado 2020