SARS-CoV-2 S2P spike ages through distinct states with altered immunogenicity

por Olia, Adam S., Tsybovsky, Yaroslav, Chen, Steven J., Liu, Cuiping, Nazzari, Alexandra F., Ou, Li, Wang, Lingshu, Kong, Wing-Pui, Leung, Kwan, Liu, Tracy, Stephens, Tyler, Teng, I-Ting, Wang, Shuishu, Yang, Eun Sung, Zhang, Baoshan, Zhang, Yi, Zhou, Tongqing, Mascola, John R., Kwong, Peter D.
Publicado 2021

Human CD4-Binding Site Antibody Elicited by Polyvalent DNA Prime-Protein Boost Vaccine Neutralizes Cross-Clade Tier-2-HIV Strains

por Wang, Shixia, Chan, Kun-Wei, Wei, Danlan, Ma, Xiuwen, Liu, Shuying, Hu, Guangnan, Park, Saeyoung, Pan, Ruimin, Gu, Ying, Nazzari, Alexandra F., Olia, Adam S., Xu, Kai, Lin, Bob C., Louder, Mark K., Doria-Rose, Nicole A., Montefiori, David, Seaman, Michael S., Zhou, Tongqing, Kwong, Peter D., Arthos, James, Kong, Xiang-Peng, Lu, Shan
Publicado 2023

Newcastle Disease Virus-Like Particles Displaying Prefusion-Stabilized SARS-CoV-2 Spikes Elicit Potent Neutralizing Responses

por Yang, Yongping, Shi, Wei, Abiona, Olubukola M., Nazzari, Alexandra, Olia, Adam S., Ou, Li, Phung, Emily, Stephens, Tyler, Tsybovsky, Yaroslav, Verardi, Raffaello, Wang, Shuishu, Werner, Anne, Yap, Christina, Ambrozak, David, Bylund, Tatsiana, Liu, Tracy, Nguyen, Richard, Wang, Lingshu, Zhang, Baoshan, Zhou, Tongqing, Chuang, Gwo-Yu, Graham, Barney S., Mascola, John R., Corbett, Kizzmekia S., Kwong, Peter D.
Publicado 2021

Molecular probes of spike ectodomain and its subdomains for SARS-CoV-2 variants, Alpha through Omicron

por Teng, I-Ting, Nazzari, Alexandra F., Choe, Misook, Liu, Tracy, Oliveira de Souza, Matheus, Petrova, Yuliya, Tsybovsky, Yaroslav, Wang, Shuishu, Zhang, Baoshan, Artamonov, Mykhaylo, Madan, Bharat, Huang, Aric, Lopez Acevedo, Sheila N., Pan, Xiaoli, Ruckwardt, Tracy J., DeKosky, Brandon J., Mascola, John R., Misasi, John, Sullivan, Nancy J., Zhou, Tongqing, Kwong, Peter D.
Publicado 2021

Molecular probes of spike ectodomain and its subdomains for SARS-CoV-2 variants, Alpha through Omicron

por Teng, I-Ting, Nazzari, Alexandra F., Choe, Misook, Liu, Tracy, Oliveira de Souza, Matheus, Petrova, Yuliya, Tsybovsky, Yaroslav, Wang, Shuishu, Zhang, Baoshan, Artamonov, Mykhaylo, Madan, Bharat, Huang, Aric, Lopez Acevedo, Sheila N., Pan, Xiaoli, Ruckwardt, Tracy J., DeKosky, Brandon J., Mascola, John R., Misasi, John, Sullivan, Nancy J., Zhou, Tongqing, Kwong, Peter D.
Publicado 2022

Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains

por Zhou, Tongqing, Tsybovsky, Yaroslav, Gorman, Jason, Rapp, Micah, Cerutti, Gabriele, Chuang, Gwo-Yu, Katsamba, Phinikoula S., Sampson, Jared M., Schön, Arne, Bimela, Jude, Boyington, Jeffrey C., Nazzari, Alexandra, Olia, Adam S., Shi, Wei, Sastry, Mallika, Stephens, Tyler, Stuckey, Jonathan, Teng, I-Ting, Wang, Pengfei, Wang, Shuishu, Zhang, Baoshan, Friesner, Richard A., Ho, David D., Mascola, John R., Shapiro, Lawrence, Kwong, Peter D.
Publicado 2020

Development of Neutralization Breadth against Diverse HIV‐1 by Increasing Ab–Ag Interface on V2

por Gao, Nan, Gai, Yanxin, Meng, Lina, Wang, Chu, Wang, Wei, Li, Xiaojun, Gu, Tiejun, Louder, Mark K., Doria‐Rose, Nicole A., Wiehe, Kevin, Nazzari, Alexandra F., Olia, Adam S., Gorman, Jason, Rawi, Reda, Wu, Wenmin, Smith, Clayton, Khant, Htet, de Val, Natalia, Yu, Bin, Luo, Junhong, Niu, Haitao, Tsybovsky, Yaroslav, Liao, Huaxin, Kepler, Thomas B., Kwong, Peter D., Mascola, John R., Qin, Chuan, Zhou, Tongqing, Yu, Xianghui, Gao, Feng
Publicado 2022

Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes

por Zhou, Tongqing, Teng, I-Ting, Olia, Adam S., Cerutti, Gabriele, Gorman, Jason, Nazzari, Alexandra, Shi, Wei, Tsybovsky, Yaroslav, Wang, Lingshu, Wang, Shuishu, Zhang, Baoshan, Zhang, Yi, Katsamba, Phinikoula S., Petrova, Yuliya, Banach, Bailey B., Fahad, Ahmed S., Liu, Lihong, Lopez Acevedo, Sheila N., Madan, Bharat, de Souza, Matheus Oliveira, Pan, Xiaoli, Wang, Pengfei, Wolfe, Jacy R., Yin, Michael, Ho, David D., Phung, Emily, DiPiazza, Anthony, Chang, Lauren, Abiona, Olubukula, Corbett, Kizzmekia S., DeKosky, Brandon J., Graham, Barney S., Mascola, John R., Misasi, John, Ruckwardt, Tracy, Sullivan, Nancy J., Shapiro, Lawrence, Kwong, Peter D.
Publicado 2020

Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes

por Zhou, Tongqing, Teng, I-Ting, Olia, Adam S., Cerutti, Gabriele, Gorman, Jason, Nazzari, Alexandra, Shi, Wei, Tsybovsky, Yaroslav, Wang, Lingshu, Wang, Shuishu, Zhang, Baoshan, Zhang, Yi, Katsamba, Phinikoula S., Petrova, Yuliya, Banach, Bailey B., Fahad, Ahmed S., Liu, Lihong, Lopez Acevedo, Sheila N., Madan, Bharat, Oliveira de Souza, Matheus, Pan, Xiaoli, Wang, Pengfei, Wolfe, Jacy R., Yin, Michael, Ho, David D., Phung, Emily, DiPiazza, Anthony, Chang, Lauren A., Abiona, Olubukola M., Corbett, Kizzmekia S., DeKosky, Brandon J., Graham, Barney S., Mascola, John R., Misasi, John, Ruckwardt, Tracy, Sullivan, Nancy J., Shapiro, Lawrence, Kwong, Peter D.
Publicado 2020

Paired heavy- and light-chain signatures contribute to potent SARS-CoV-2 neutralization in public antibody responses

por Banach, Bailey B., Cerutti, Gabriele, Fahad, Ahmed S., Shen, Chen-Hsiang, Oliveira De Souza, Matheus, Katsamba, Phinikoula S., Tsybovsky, Yaroslav, Wang, Pengfei, Nair, Manoj S., Huang, Yaoxing, Francino-Urdániz, Irene M., Steiner, Paul J., Gutiérrez-González, Matías, Liu, Lihong, López Acevedo, Sheila N., Nazzari, Alexandra F., Wolfe, Jacy R., Luo, Yang, Olia, Adam S., Teng, I-Ting, Yu, Jian, Zhou, Tongqing, Reddem, Eswar R., Bimela, Jude, Pan, Xiaoli, Madan, Bharat, Laflin, Amy D., Nimrania, Rajani, Yuen, Kwok-Yung, Whitehead, Timothy A., Ho, David D., Kwong, Peter D., Shapiro, Lawrence, DeKosky, Brandon J.
Publicado 2021

Antibodies with potent and broad neutralizing activity against antigenically diverse and highly transmissible SARS-CoV-2 variants

por Wang, Lingshu, Zhou, Tongqing, Zhang, Yi, Yang, Eun Sung, Schramm, Chaim A., Shi, Wei, Pegu, Amarendra, Oloninyi, Olamide K., Ransier, Amy, Darko, Samuel, Narpala, Sandeep R., Hatcher, Christian, Martinez, David R., Tsybovsky, Yaroslav, Phung, Emily, Abiona, Olubukola M., Cale, Evan M., Chang, Lauren A., Corbett, Kizzmekia S., DiPiazza, Anthony T., Gordon, Ingelise J., Leung, Kwanyee, Liu, Tracy, Mason, Rosemarie D., Nazzari, Alexandra, Novik, Laura, Olia, Adam S., Doria-Rose, Nicole A., Stephens, Tyler, Stringham, Christopher D., Talana, Chloe Adrienna, Teng, I-Ting, Wagner, Danielle, Widge, Alicia T., Zhang, Baoshan, Roederer, Mario, Ledgerwood, Julie E., Ruckwardt, Tracy J., Gaudinski, Martin R., Baric, Ralph S., Graham, Barney S., McDermott, Adrian B., Douek, Daniel C., Kwong, Peter D., Mascola, John R, Sullivan, Nancy J., Misasi, John
Publicado 2021

Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants

por Wang, Lingshu, Zhou, Tongqing, Zhang, Yi, Yang, Eun Sung, Schramm, Chaim A., Shi, Wei, Pegu, Amarendra, Oloniniyi, Olamide K., Henry, Amy R., Darko, Samuel, Narpala, Sandeep R., Hatcher, Christian, Martinez, David R., Tsybovsky, Yaroslav, Phung, Emily, Abiona, Olubukola M., Antia, Avan, Cale, Evan M., Chang, Lauren A., Choe, Misook, Corbett, Kizzmekia S., Davis, Rachel L., DiPiazza, Anthony T., Gordon, Ingelise J., Hait, Sabrina Helmold, Hermanus, Tandile, Kgagudi, Prudence, Laboune, Farida, Leung, Kwanyee, Liu, Tracy, Mason, Rosemarie D., Nazzari, Alexandra F., Novik, Laura, O’Connell, Sarah, O’Dell, Sijy, Olia, Adam S., Schmidt, Stephen D., Stephens, Tyler, Stringham, Christopher D., Talana, Chloe Adrienna, Teng, I-Ting, Wagner, Danielle A., Widge, Alicia T., Zhang, Baoshan, Roederer, Mario, Ledgerwood, Julie E., Ruckwardt, Tracy J., Gaudinski, Martin R., Moore, Penny L., Doria-Rose, Nicole A., Baric, Ralph S., Graham, Barney S., McDermott, Adrian B., Douek, Daniel C., Kwong, Peter D., Mascola, John R., Sullivan, Nancy J., Misasi, John
Publicado 2021