Blocking Cytochrome c Activity within Intact Neurons Inhibits Apoptosis

por Neame, Stephen J., Rubin, Lee L., Philpott, Karen L.
Publicado 1998

Microglial signalling pathway deficits associated with the patient derived R47H TREM2 variants linked to AD indicate inability to activate inflammasome

por Cosker, Katharina, Mallach, Anna, Limaye, Janhavi, Piers, Thomas M., Staddon, James, Neame, Stephen J., Hardy, John, Pocock, Jennifer M.
Publicado 2021

Human Induced Pluripotent Stem Cell-Derived Microglia-Like Cells Harboring TREM2 Missense Mutations Show Specific Deficits in Phagocytosis

por Garcia-Reitboeck, Pablo, Phillips, Alexandra, Piers, Thomas M., Villegas-Llerena, Claudio, Butler, Matt, Mallach, Anna, Rodrigues, Celia, Arber, Charles E., Heslegrave, Amanda, Zetterberg, Henrik, Neumann, Harald, Neame, Stephen, Houlden, Henry, Hardy, John, Pocock, Jennifer M.
Publicado 2018

Selection and structural characterization of anti-TREM2 scFvs that reduce levels of shed ectodomain

por Szykowska, Aleksandra, Chen, Yu, Smith, Thomas B., Preger, Charlotta, Yang, Jingjing, Qian, Dongming, Mukhopadhyay, Shubhashish M., Wigren, Edvard, Neame, Stephen J., Gräslund, Susanne, Persson, Helena, Atkinson, Peter J., Di Daniel, Elena, Mead, Emma, Wang, John, Davis, John B., Burgess-Brown, Nicola A., Bullock, Alex N.
Publicado 2021