Single-molecule visualisation of DNA G-quadruplex formation in live cells

por Di Antonio, Marco, Ponjavic, Aleks, Radzevičius, Antanas, Ranasinghe, Rohan T., Catalano, Marco, Zhang, Xiaoyun, Shen, Jiazhen, Needham, Lisa-Maria, Lee, Steven F., Klenerman, David, Balasubramanian, Shankar
Publicado 2020

Single-molecule fluorescence detection of a tricyclic nucleoside analogue

por Samaan, George N., Wyllie, Mckenzie K., Cizmic, Julian M., Needham, Lisa-Maria, Nobis, David, Ngo, Katrina, Andersen, Susan, Magennis, Steven W., Lee, Steven F., Purse, Byron W.
Publicado 2020

Label-free observation of individual solution phase molecules

por Needham, Lisa-Maria, Saavedra, Carlos, Rasch, Julia K., Sole-Barber, Daniel, Schweitzer, Beau S., Fairhall, Alex J., Vollbrecht, Cecilia H., Mehlenbacher, Brandon, Zhang, Zhao, Tenbrake, Lukas, Pfeifer, Hannes, Chapman, Edwin R., Goldsmith, Randall H.
Publicado 2023

Bifunctional fluorescent probes for detection of amyloid aggregates and reactive oxygen species

por Needham, Lisa-Maria, Weber, Judith, Fyfe, James W. B., Kabia, Omaru M., Do, Dung T., Klimont, Ewa, Zhang, Yu, Rodrigues, Margarida, Dobson, Christopher M., Ghandi, Sonia, Bohndiek, Sarah E., Snaddon, Thomas N., Lee, Steven F.
Publicado 2018

Correction to ‘Bifunctional fluorescent probes for detection of amyloid aggregates and reactive oxygen species’

por Needham, Lisa-Maria, Weber, Judith, Fyfe, James W. B., Kabia, Omaru M., Do, Dung T., Klimont, Ewa, Zhang, Yu, Rodrigues, Margarida, Dobson, Christopher M., Gandhi, Sonia, Bohndiek, Sarah E., Snaddon, Thomas N., Lee, Steven F.
Publicado 2018

FRET-enhanced photostability allows improved single-molecule tracking of proteins and protein complexes in live mammalian cells

por Basu, Srinjan, Needham, Lisa-Maria, Lando, David, Taylor, Edward J. R., Wohlfahrt, Kai J., Shah, Devina, Boucher, Wayne, Tan, Yi Lei, Bates, Lawrence E., Tkachenko, Olga, Cramard, Julie, Lagerholm, B. Christoffer, Eggeling, Christian, Hendrich, Brian, Klenerman, Dave, Lee, Steven F., Laue, Ernest D.
Publicado 2018

Rational design of a conformation-specific antibody for the quantification of Aβ oligomers

por Aprile, Francesco A., Sormanni, Pietro, Podpolny, Marina, Chhangur, Shianne, Needham, Lisa-Maria, Ruggeri, Francesco S., Perni, Michele, Limbocker, Ryan, Heller, Gabriella T., Sneideris, Tomas, Scheidt, Tom, Mannini, Benedetta, Habchi, Johnny, Lee, Steven F., Salinas, Patricia C., Knowles, Tuomas P. J., Dobson, Christopher M., Vendruscolo, Michele
Publicado 2020

ThX – a next-generation probe for the early detection of amyloid aggregates

por Needham, Lisa-Maria, Weber, Judith, Varela, Juan A., Fyfe, James W. B., Do, Dung T., Xu, Catherine K., Tutton, Luke, Cliffe, Rachel, Keenlyside, Benjamin, Klenerman, David, Dobson, Christopher M., Hunter, Christopher A., Müller, Karin H., O'Holleran, Kevin, Bohndiek, Sarah E., Snaddon, Thomas N., Lee, Steven F.
Publicado 2020

Wild-type sTREM2 blocks Aβ aggregation and neurotoxicity, but the Alzheimer's R47H mutant increases Aβ aggregation

por Vilalta, Anna, Zhou, Ye, Sevalle, Jean, Griffin, Jennifer K., Satoh, Kanayo, Allendorf, David H., De, Suman, Puigdellívol, Mar, Bruzas, Arturas, Burguillos, Miguel A., Dodd, Roger B., Chen, Fusheng, Zhang, Yalun, Flagmeier, Patrick, Needham, Lisa-Maria, Enomoto, Masahiro, Qamar, Seema, Henderson, James, Walter, Jochen, Fraser, Paul E., Klenerman, David, Lee, Steven F., St George-Hyslop, Peter, Brown, Guy C.
Publicado 2021

Poly(ADP-Ribose) Links the DNA Damage Response and Biomineralization

por Müller, Karin H., Hayward, Robert, Rajan, Rakesh, Whitehead, Meredith, Cobb, Andrew M., Ahmad, Sadia, Sun, Mengxi, Goldberga, Ieva, Li, Rui, Bashtanova, Uliana, Puszkarska, Anna M., Reid, David G., Brooks, Roger A., Skepper, Jeremy N., Bordoloi, Jayanta, Chow, Wing Ying, Oschkinat, Hartmut, Groombridge, Alex, Scherman, Oren A., Harrison, James A., Verhulst, Anja, D’Haese, Patrick C., Neven, Ellen, Needham, Lisa-Maria, Lee, Steven F., Shanahan, Catherine M., Duer, Melinda J.
Publicado 2019