The Effects of Anthocyanins and Their Microbial Metabolites on the Expression and Enzyme Activities of Paraoxonase 1, an Important Marker of HDL Function

por Aboufarrag, Hassan T., Needs, Paul W., Rimbach, Gerald, Kroon, Paul A.
Publicado 2019

MK571 inhibits phase-2 conjugation of flavonols by Caco-2/TC7 cells, but does not specifically inhibit their apical efflux()

por Barrington, Robert D., Needs, Paul W., Williamson, Gary, Kroon, Paul A.
Publicado 2015

Anti‐Inflammatory Effects of Quercetin on High‐Glucose and Pro‐Inflammatory Cytokine Challenged Vascular Endothelial Cell Metabolism

por Ozyel, Besim, Le Gall, Gwénaëlle, Needs, Paul W., Kroon, Paul A.
Publicado 2021

Hydrophobic Interactions Drive Binding between Vascular Endothelial Growth Factor-A (VEGFA) and Polyphenolic Inhibitors

por Perez-Moral, Natalia, Needs, Paul W., Moyle, Christina W.A., Kroon, Paul A.
Publicado 2019

Molecular structure‐function relationship of dietary polyphenols for inhibiting VEGF‐induced VEGFR‐2 activity

por Cerezo, Ana B., Winterbone, Mark S., Moyle, Christina W. A., Needs, Paul W., Kroon, Paul A.
Publicado 2015

An LC-MS/MS Method to Measure S-Methyl-l-Cysteine and S-Methyl-l-Cysteine Sulfoxide in Human Specimens Using Isotope Labelled Internal Standards

por Sivapalan, Tharsini, Melchini, Antonietta, Coode-Bate, Jack, Needs, Paul W., Mithen, Richard F., Saha, Shikha
Publicado 2019

A One-Step Extraction and Luminescence Assay for Quantifying Glucose and ATP Levels in Cultured HepG2 Cells

por Csepregi, Rita, Temesfői, Viktória, Sali, Nikolett, Poór, Miklós, W. Needs, Paul, A. Kroon, Paul, Kőszegi, Tamás
Publicado 2018

Monomeric Flavanols Are More Efficient Substrates for Gut Microbiota Conversion to Hydroxyphenyl‐γ‐Valerolactone Metabolites Than Oligomeric Procyanidins: A Randomized, Placebo‐Con...

por Hollands, Wendy J, Philo, Mark, Perez‐Moral, Natalia, Needs, Paul W, Savva, George M, Kroon, Paul A
Publicado 2020

Plant Bioactives and the Prevention of Prostate Cancer: Evidence from Human Studies

por Livingstone, Tracey L., Beasy, Gemma, Mills, Robert D., Plumb, Jenny, Needs, Paul W., Mithen, Richard, Traka, Maria H.
Publicado 2019

Potent inhibition of VEGFR-2 activation by tight binding of green tea epigallocatechin gallate and apple procyanidins to VEGF: Relevance to angiogenesis

por Moyle, Christina W A, Cerezo, Ana B, Winterbone, Mark S, Hollands, Wendy J, Alexeev, Yuri, Needs, Paul W, Kroon, Paul A
Publicado 2015

Bioavailability of Glucoraphanin and Sulforaphane from High‐Glucoraphanin Broccoli

por Sivapalan, Tharsini, Melchini, Antonietta, Saha, Shikha, Needs, Paul W., Traka, Maria H., Tapp, Henri, Dainty, Jack R., Mithen, Richard F.
Publicado 2018

Contribution of the Glucosinolate Fraction to the Overall Antioxidant Potential, Cytoprotection against Oxidative Insult and Antimicrobial Activity of Eruca sativa Mill. Leaves Ext...

por Taviano, Maria Fernanda, Melchini, Antonietta, Filocamo, Angela, Costa, Chiara, Catania, Stefania, Raciti, Roberto, Saha, Shikha, Needs, Paul, Bisignano, Giuseppe Giovanni, Miceli, Natalizia
Publicado 2017

Inhibitory Effects of Quercetin and Its Main Methyl, Sulfate, and Glucuronic Acid Conjugates on Cytochrome P450 Enzymes, and on OATP, BCRP and MRP2 Transporters

por Mohos, Violetta, Fliszár-Nyúl, Eszter, Ungvári, Orsolya, Kuffa, Katalin, Needs, Paul W., Kroon, Paul A., Telbisz, Ágnes, Özvegy-Laczka, Csilla, Poór, Miklós
Publicado 2020

Inhibitory Effects of Quercetin and Its Human and Microbial Metabolites on Xanthine Oxidase Enzyme

por Mohos, Violetta, Pánovics, Attila, Fliszár-Nyúl, Eszter, Schilli, Gabriella, Hetényi, Csaba, Mladěnka, Přemysl, Needs, Paul W., Kroon, Paul A., Pethő, Gábor, Poór, Miklós
Publicado 2019

Development, validation and evaluation of an analytical method for the determination of monomeric and oligomeric procyanidins in apple extracts

por Hollands, Wendy J., Voorspoels, Stefan, Jacobs, Griet, Aaby, Kjersti, Meisland, Ane, Garcia-Villalba, Rocio, Tomas-Barberan, Francisco, Piskula, Mariusz K., Mawson, Deborah, Vovk, Irena, Needs, Paul W., Kroon, Paul A.
Publicado 2017

Accumulation of Dietary S‐Methyl Cysteine Sulfoxide in Human Prostate Tissue

por Coode‐Bate, Jack, Sivapalan, Tharsini, Melchini, Antonietta, Saha, Shikha, Needs, Paul W., Dainty, Jack R., Maicha, Jean‐Bapiste, Beasy, Gemma, Traka, Maria H., Mills, Robert D., Ball, Richard Y., Mithen, Richard F.
Publicado 2019

Broccoli Consumption Interacts with GSTM1 to Perturb Oncogenic Signalling Pathways in the Prostate

por Traka, Maria, Gasper, Amy V., Melchini, Antonietta, Bacon, James R., Needs, Paul W., Frost, Victoria, Chantry, Andrew, Jones, Alexandra M. E., Ortori, Catharine A., Barrett, David A., Ball, Richard Y., Mills, Robert D., Mithen, Richard F.
Publicado 2008

Transcriptional changes in prostate of men on active surveillance after a 12-mo glucoraphanin-rich broccoli intervention—results from the Effect of Sulforaphane on prostate CAncer...

por Traka, Maria H, Melchini, Antonietta, Coode-Bate, Jack, Al Kadhi, Omar, Saha, Shikha, Defernez, Marianne, Troncoso-Rey, Perla, Kibblewhite, Helen, O'Neill, Carmel M, Bernuzzi, Federico, Mythen, Laura, Hughes, Jackie, Needs, Paul W, Dainty, Jack R, Savva, George M, Mills, Robert D, Ball, Richard Y, Cooper, Colin S, Mithen, Richard F
Publicado 2019