Heterozygous mutation of cysteine(528) in XPO1 is sufficient for resistance to selective inhibitors of nuclear export

por Neggers, Jasper Edgar, Vanstreels, Els, Baloglu, Erkan, Shacham, Sharon, Landesman, Yosef, Daelemans, Dirk
Publicado 2016

enAsCas12a Enables CRISPR-Directed Evolution to Screen for Functional Drug Resistance Mutations in Sequences Inaccessible to SpCas9

por Neggers, Jasper Edgar, Jacquemyn, Maarten, Dierckx, Tim, Kleinstiver, Benjamin Peter, Thibaut, Hendrik Jan, Daelemans, Dirk
Publicado 2021

Target identification of small molecules using large-scale CRISPR-Cas mutagenesis scanning of essential genes

por Neggers, Jasper Edgar, Kwanten, Bert, Dierckx, Tim, Noguchi, Hiroki, Voet, Arnout, Bral, Lotte, Minner, Kristien, Massant, Bob, Kint, Nicolas, Delforge, Michel, Vercruysse, Thomas, Baloglu, Erkan, Senapedis, William, Jacquemyn, Maarten, Daelemans, Dirk
Publicado 2018