Design of Membrane Active Peptides Considering Multi-Objective Optimization for Biomedical Application

por Röckendorf, Niels, Nehls, Christian, Gutsmann, Thomas
Publicado 2022

Flagellin lysine methyltransferase FliB catalyzes a [4Fe-4S] mediated methyl transfer reaction

por Wang, Chu, Nehls, Christian, Baabe, Dirk, Burghaus, Olaf, Hurwitz, Robert, Gutsmann, Thomas, Bröring, Martin, Kolbe, Michael
Publicado 2021

Measuring Thousands of Single-Vesicle Leakage Events Reveals the Mode of Action of Antimicrobial Peptides

por Al Nahas, Kareem, Fletcher, Marcus, Hammond, Katharine, Nehls, Christian, Cama, Jehangir, Ryadnov, Maxim G., Keyser, Ulrich F.
Publicado 2022

A Comparison between SARS-CoV-2 and Gram-Negative Bacteria-Induced Hyperinflammation and Sepsis

por Brandenburg, Klaus, Ferrer-Espada, Raquel, Martinez-de-Tejada, Guillermo, Nehls, Christian, Fukuoka, Satoshi, Mauss, Karl, Weindl, Günther, Garidel, Patrick
Publicado 2023

The Beauty of Asymmetric Membranes: Reconstitution of the Outer Membrane of Gram-Negative Bacteria

por Paulowski, Laura, Donoghue, Annemarie, Nehls, Christian, Groth, Sabrina, Koistinen, Max, Hagge, Sven O., Böhling, Arne, Winterhalter, Mathias, Gutsmann, Thomas
Publicado 2020

ADAM10 sheddase activation is controlled by cell membrane asymmetry

por Bleibaum, Florian, Sommer, Anselm, Veit, Martin, Rabe, Björn, Andrä, Jörg, Kunzelmann, Karl, Nehls, Christian, Correa, Wilmar, Gutsmann, Thomas, Grötzinger, Joachim, Bhakdi, Sucharit, Reiss, Karina
Publicado 2019

Hit-optimization using target-directed dynamic combinatorial chemistry: development of inhibitors of the anti-infective target 1-deoxy-d-xylulose-5-phosphate synthase

por Jumde, Ravindra P., Guardigni, Melissa, Gierse, Robin M., Alhayek, Alaa, Zhu, Di, Hamid, Zhoor, Johannsen, Sandra, Elgaher, Walid A. M., Neusens, Philipp J., Nehls, Christian, Haupenthal, Jörg, Reiling, Norbert, Hirsch, Anna K. H.
Publicado 2021

Phosphatidylserine exposure is required for ADAM17 sheddase function

por Sommer, Anselm, Kordowski, Felix, Büch, Joscha, Maretzky, Thorsten, Evers, Astrid, Andrä, Jörg, Düsterhöft, Stefan, Michalek, Matthias, Lorenzen, Inken, Somasundaram, Prasath, Tholey, Andreas, Sönnichsen, Frank D., Kunzelmann, Karl, Heinbockel, Lena, Nehls, Christian, Gutsmann, Thomas, Grötzinger, Joachim, Bhakdi, Sucharit, Reiss, Karina
Publicado 2016