Phosphate acts directly on the calcium-sensing receptor to stimulate parathyroid hormone secretion

por Centeno, Patricia P., Herberger, Amanda, Mun, Hee-Chang, Tu, Chialing, Nemeth, Edward F., Chang, Wenhan, Conigrave, Arthur D., Ward, Donald T.
Publicado 2019

OR23-03 Sustained Normalization Of Mineral Homeostasis In Autosomal Dominant Hypocalcemia Type 1: Results From A Phase 2 Study Over 18 Months Of Encaleret (CLTX-305) Treatment (NCT...

por Ilana Gafni, Rachel, Ruth Hartley, Iris, Lauter Roszko, Kelly, Nemeth, Edward F, Pozo, Karen A, Mathew, Arun, Scott Roberts, Mary, Adler, Scott H, Collins, Michael T
Publicado 2023

Calcilytic NPSP795 Increases Plasma Calcium and PTH in an Autosomal Dominant Hypocalcemia Type 1 Mouse Model

por Hannan, Fadil M, Gorvin, Caroline M, Babinsky, Valerie N, Olesen, Mie K, Stewart, Michelle, Wells, Sara, Cox, Roger D, Nemeth, Edward F, Thakker, Rajesh V
Publicado 2020

A Phase 2B, Open-Label, Dose-Ranging Study of Encaleret (CLTX-305) in Autosomal Dominant Hypocalcemia Type 1 (ADH1)

por Gafni, Rachel Ilana, Hartley, Iris Ruth, Roszko, Kelly Lauter, Nemeth, Edward F, Pozo, Karen A, Sani-Grosso, Ramei, Sridhar, Ananth, Fox, Jonathan C, Collins, Michael T
Publicado 2021

Autosomal Dominant Hypocalcemia Type 1: A Systematic Review

por Roszko, Kelly L, Stapleton Smith, Lyndsay M, Sridhar, Ananth V, Roberts, Mary Scott, Hartley, Iris R, Gafni, Rachel I, Collins, Michael T, Fox, Jonathan C, Nemeth, Edward F
Publicado 2022

The Effects of Encaleret (CLTX-305) on Mineral Physiology in Autosomal Dominant Hypocalcemia Type 1 (ADH1) Demonstrate Proof-of-Concept: Early Results From an Ongoing Phase 2b, Ope...

por Gafni, Rachel Ilana, Hartley, Iris Ruth, Roszko, Kelly Lauter, Nemeth, Edward F, Pozo, Karen A, Sani-Grosso, Ramei, Sridhar, Ananth, Kennedy, William D, Fox, Jonathan C, Collins, Michael T
Publicado 2021