Genetics of Rheumatoid Arthritis

por Nepom, Gerald T
Publicado 2000

Synergistic targeting of immunologic pathways to empower durable tolerance therapies

por Nepom, Gerald T.
Publicado 2022

Lost in translation: barriers to implementing clinical immunotherapeutics for autoimmunity

por von Herrath, Matthias G., Nepom, Gerald T.
Publicado 2005

Uncovering Pathways to Personalized Therapies in Type 1 Diabetes

por Linsley, Peter S., Greenbaum, Carla J., Nepom, Gerald T.
Publicado 2021

Investigating the Role of T-Cell Avidity and Killing Efficacy in Relation to Type 1 Diabetes Prediction

por Khadra, Anmar, Pietropaolo, Massimo, Nepom, Gerald T., Sherman, Arthur
Publicado 2011

Restoring the balance: immunotherapeutic combinations for autoimmune disease

por Smilek, Dawn E., Ehlers, Mario R., Nepom, Gerald T.
Publicado 2014

Analysis of overlapping T- and B-Cell antigenic sites on rubella virus E1 envelope protein influence of HLA-DR4 polymorphism on T-cell clonal recognition

por Ou, Dawei, Mitchell, Leslie Ann, Ho, Margaret, Décarie, Diane, Tingle, Aubrey J., Nepom, Gerald T., Lacroix, Martial, Zrein, Maan
Publicado 1994

IL-10 Induction from Implants Delivering Pancreatic Islets and Hyaluronan

por Bollyky, Paul L., Vernon, Robert B., Falk, Ben A., Preisinger, Anton, Gooden, Michel D., Nepom, Gerald T., Gebe, John A.
Publicado 2013

Approaches to Establishing Tolerance in Immune Mediated Diseases

por Huffaker, Michelle F., Sanda, Srinath, Chandran, Sindhu, Chung, Sharon A., St. Clair, E. William, Nepom, Gerald T., Smilek, Dawn E.
Publicado 2021

Antibiotic-refractory Lyme arthritis is associated with HLA-DR molecules that bind a Borrelia burgdorferi peptide

por Steere, Allen C., Klitz, William, Drouin, Elise E., Falk, Ben A., Kwok, William W., Nepom, Gerald T., Baxter-Lowe, Lee Ann
Publicado 2006

Exhausted-like CD8(+) T cell phenotypes linked to C-peptide preservation in alefacept-treated T1D subjects

por Diggins, Kirsten E., Serti, Elisavet, Muir, Virginia, Rosasco, Mario, Lu, TingTing, Balmas, Elisa, Nepom, Gerald, Long, S. Alice, Linsley, Peter S.
Publicado 2021

Avidity-Dependent Programming of Autoreactive T Cells in T1D

por Durinovic-Belló, Ivana, Gersuk, Vivian H., Ni, Chester, Wu, Rebecca, Thorpe, Jerill, Jospe, Nicholas, Sanda, Srinath, Greenbaum, Carla J., Nepom, Gerald T.
Publicado 2014

The Toll-Like Receptor Signaling Molecule Myd88 Contributes to Pancreatic Beta-Cell Homeostasis in Response to Injury

por Bollyky, Paul L., Bice, Jeffrey B., Sweet, Ian R., Falk, Ben A., Gebe, John A., Clark, April E., Gersuk, Vivian H., Aderem, Alan, Hawn, Thomas R., Nepom, Gerald T.
Publicado 2009

The insulin A-chain epitope recognized by human T cells is posttranslationally modified

por Mannering, Stuart I., Harrison, Leonard C., Williamson, Nicholas A., Morris, Jessica S., Thearle, Daniel J., Jensen, Kent P., Kay, Thomas W.H., Rossjohn, Jamie, Falk, Ben A., Nepom, Gerald T., Purcell, Anthony W.
Publicado 2005

Self-reactive human CD4 T cell clones form unusual immunological synapses

por Schubert, David A., Gordo, Susana, Sabatino, Joseph J., Vardhana, Santosh, Gagnon, Etienne, Sethi, Dhruv K., Seth, Nilufer P., Choudhuri, Kaushik, Reijonen, Helena, Nepom, Gerald T., Evavold, Brian D., Dustin, Michael L., Wucherpfennig, Kai W.
Publicado 2012

HLA alleles and sustained peanut consumption promote IgG4 responses in subjects protected from peanut allergy

por Kanchan, Kanika, Grinek, Stepan, Bahnson, Henry T., Ruczinski, Ingo, Shankar, Gautam, Larson, David, Du Toit, George, Barnes, Kathleen C., Sampson, Hugh A., Suarez-Farinas, Mayte, Lack, Gideon, Nepom, Gerald T., Cerosaletti, Karen, Mathias, Rasika A.
Publicado 2022

Rebranding asymptomatic type 1 diabetes: the case for autoimmune beta cell disorder as a pathological and diagnostic entity

por Bonifacio, Ezio, Mathieu, Chantal, Nepom, Gerald T., Ziegler, Anette-G., Anhalt, Henry, Haller, Michael J., Harrison, Leonard C., Hebrok, Matthias, Kushner, Jake A., Norris, Jill M., Peakman, Mark, Powers, Alvin C., Todd, John A., Atkinson, Mark A.
Publicado 2016

Discriminative T cell recognition of cross-reactive islet-antigens is associated with HLA-DQ8 transdimer–mediated autoimmune diabetes

por Chow, I-Ting, Gates, Theresa J., Papadopoulos, George K., Moustakas, Antonis K., Kolawole, Elizabeth M., Notturno, Richard J., McGinty, John W., Torres-Chinn, Nadia, James, Eddie A., Greenbaum, Carla, Nepom, Gerald T., Evavold, Brian D., Kwok, William W.
Publicado 2019

A Preclinical Consortium Approach for Assessing the Efficacy of Combined Anti-CD3 Plus IL-1 Blockade in Reversing New-Onset Autoimmune Diabetes in NOD Mice

por Gill, Ronald G., Pagni, Philippe P., Kupfer, Tinalyn, Wasserfall, Clive H., Deng, Songyan, Posgai, Amanda, Manenkova, Yulia, Bel Hani, Amira, Straub, Laura, Bernstein, Philip, Atkinson, Mark A., Herold, Kevan C., von Herrath, Matthias, Staeva, Teodora, Ehlers, Mario R., Nepom, Gerald T.
Publicado 2016

HLA-associated outcomes in peanut oral immunotherapy trials identify mechanistic and clinical determinants of therapeutic success

por Kanchan, Kanika, Shankar, Gautam, Huffaker, Michelle F., Bahnson, Henry T., Chinthrajah, R Sharon, Sanda, Srinath, Manohar, Monali, Ling, Hua, Paschall, Justin E., Toit, George Du, Ruczinski, Ingo, Togias, Alkis, Lack, Gideon, Nadeau, Kari C., Jones, Stacie M., Nepom, Gerald T., Mathias, Rasika A.
Publicado 2022