Targeting mTOR in Acute Lymphoblastic Leukemia

por Simioni, Carolina, Martelli, Alberto M., Zauli, Giorgio, Melloni, Elisabetta, Neri, Luca M.
Publicado 2019

The Complexity of the Tumor Microenvironment and Its Role in Acute Lymphoblastic Leukemia: Implications for Therapies

por Simioni, Carolina, Conti, Ilaria, Varano, Gabriele, Brenna, Cinzia, Costanzi, Eva, Neri, Luca M.
Publicado 2021

miRNAs as Influencers of Cell–Cell Communication in Tumor Microenvironment

por Conti, Ilaria, Varano, Gabriele, Simioni, Carolina, Laface, Ilaria, Milani, Daniela, Rimondi, Erika, Neri, Luca M.
Publicado 2020

Oxidative stress: role of physical exercise and antioxidant nutraceuticals in adulthood and aging

por Simioni, Carolina, Zauli, Giorgio, Martelli, Alberto M., Vitale, Marco, Sacchetti, Gianni, Gonelli, Arianna, Neri, Luca M.
Publicado 2018

Physical training interventions for children and teenagers affected by acute lymphoblastic leukemia and related treatment impairments

por Simioni, Carolina, Zauli, Giorgio, Martelli, Alberto M., Vitale, Marco, Ultimo, Simona, Milani, Daniela, Neri, Luca M.
Publicado 2018

Influence of physical exercise on microRNAs in skeletal muscle regeneration, aging and diseases

por Ultimo, Simona, Zauli, Giorgio, Martelli, Alberto M., Vitale, Marco, McCubrey, James A., Capitani, Silvano, Neri, Luca M.
Publicado 2018

Cardiovascular disease-related miRNAs expression: potential role as biomarkers and effects of training exercise

por Ultimo, Simona, Zauli, Giorgio, Martelli, Alberto M., Vitale, Marco, McCubrey, James A., Capitani, Silvano, Neri, Luca M.
Publicado 2018

The AKT Inhibitor MK-2206 is Cytotoxic in Hepatocarcinoma Cells Displaying Hyperphosphorylated AKT-1 and Synergizes with Conventional Chemotherapy

por Simioni, Carolina, Martelli, Alberto M., Cani, Alice, Cetin-Atalay, Rengul, McCubrey, James A., Capitani, Silvano, Neri, Luca M.
Publicado 2013

Activity of the novel mTOR inhibitor Torin-2 in B-precursor acute lymphoblastic leukemia and its therapeutic potential to prevent Akt reactivation

por Simioni, Carolina, Cani, Alice, Martelli, Alberto M., Zauli, Giorgio, Tabellini, Giovanna, McCubrey, James, Capitani, Silvano, Neri, Luca M.
Publicado 2014

Synergistic effects of selective inhibitors targeting the PI3K/AKT/mTOR pathway or NUP214-ABL1 fusion protein in human Acute Lymphoblastic Leukemia

por Simioni, Carolina, Ultimo, Simona, Martelli, Alberto M., Zauli, Giorgio, Milani, Daniela, McCubrey, James A., Capitani, Silvano, Neri, Luca M.
Publicado 2016

Impact of physical exercise in cancer survivors during and after antineoplastic treatments

por Ferioli, Martina, Zauli, Giorgio, Martelli, Alberto M., Vitale, Marco, McCubrey, James A., Ultimo, Simona, Capitani, Silvano, Neri, Luca M.
Publicado 2018

Triple Akt inhibition as a new therapeutic strategy in T-cell acute lymphoblastic leukemia

por Cani, Alice, Simioni, Carolina, Martelli, Alberto M., Zauli, Giorgio, Tabellini, Giovanna, Ultimo, Simona, McCubrey, James A., Capitani, Silvano, Neri, Luca M.
Publicado 2015

The novel dual PI3K/mTOR inhibitor NVP-BGT226 displays cytotoxic activity in both normoxic and hypoxic hepatocarcinoma cells

por Simioni, Carolina, Cani, Alice, Martelli, Alberto M., Zauli, Giorgio, Alameen, Ayman A.M., Ultimo, Simona, Tabellini, Giovanna, McCubrey, James A., Capitani, Silvano, Neri, Luca M.
Publicado 2015

PI3K isoform inhibition associated with anti Bcr-Abl drugs shows in vitro increased anti-leukemic activity in Philadelphia chromosome-positive B-acute lymphoblastic leukemia cell l...

por Ultimo, Simona, Simioni, Carolina, Martelli, Alberto M., Zauli, Giorgio, Evangelisti, Camilla, Celeghini, Claudio, McCubrey, James A., Marisi, Giorgia, Ulivi, Paola, Capitani, Silvano, Neri, Luca M.
Publicado 2017

Drug-resistance in doxorubicin-resistant FL5.12 hematopoietic cells: elevated MDR1, drug efflux and side-population positive and decreased BCL2-family member expression

por Steelman, Linda S., Abrams, Steve L., Ruvolo, Peter, Ruvolo, Vivian, Cocco, Lucio, Ratti, Stefano, Martelli, Alberto M., Neri, Luca M., Candido, Saverio, Libra, Massimo, McCubrey, James A.
Publicado 2017

Healthy CD4(+) T lymphocytes are not affected by targeted therapies against the PI3K/Akt/mTOR pathway in T-cell acute lymphoblastic leukemia

por Alameen, Ayman A.M., Simioni, Carolina, Martelli, Alberto M., Zauli, Giorgio, Ultimo, Simona, McCubrey, James A., Gonelli, Arianna, Marisi, Giorgia, Ulivi, Paola, Capitani, Silvano, Neri, Luca M.
Publicado 2016

Roles of GSK-3 and microRNAs on epithelial mesenchymal transition and cancer stem cells

por McCubrey, James A., Fitzgerald, Timothy L., Yang, Li V., Lertpiriyapong, Kvin, Steelman, Linda S., Abrams, Stephen L., Montalto, Giuseppe, Cervello, Melchiorre, Neri, Luca M., Cocco, Lucio, Martelli, Alberto M., Laidler, Piotr, Dulińska-Litewka, Joanna, Rakus, Dariusz, Gizak, Agnieszka, Nicoletti, Ferdinando, Falzone, Luca, Candido, Saverio, Libra, Massimo
Publicado 2016

Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs

por McCubrey, James A., Lertpiriyapong, Kvin, Steelman, Linda S., Abrams, Steve L., Yang, Li V., Murata, Ramiro M., Rosalen, Pedro L., Scalisi, Aurora, Neri, Luca M., Cocco, Lucio, Ratti, Stefano, Martelli, Alberto M., Laidler, Piotr, Dulińska-Litewka, Joanna, Rakus, Dariusz, Gizak, Agnieszka, Lombardi, Paolo, Nicoletti, Ferdinando, Candido, Saverio, Libra, Massimo, Montalto, Giuseppe, Cervello, Melchiorre
Publicado 2017