Dissociation of lipotoxicity and glucotoxicity in a mouse model of obesity associated diabetes: role of forkhead box O1 (FOXO1) in glucose-induced beta cell failure

por Kluth, O., Mirhashemi, F., Scherneck, S., Kaiser, D., Kluge, R., Neschen, S., Joost, H.-G., Schürmann, A.
Publicado 2010

The Epoxyeicosatrienoic Acid Pathway Enhances Hepatic Insulin Signaling and is Repressed in Insulin-Resistant Mouse Liver

por Schäfer, Alexander, Neschen, Susanne, Kahle, Melanie, Sarioglu, Hakan, Gaisbauer, Tobias, Imhof, Axel, Adamski, Jerzy, Hauck, Stefanie M., Ueffing, Marius
Publicado 2015

Retinal proteome alterations in a mouse model of type 2 diabetes

por Ly, Alice, Scheerer, Markus F., Zukunft, Sven, Muschet, Caroline, Merl, Juliane, Adamski, Jerzy, Hrabě de Angelis, Martin, Neschen, Susanne, Hauck, Stefanie M., Ueffing, Marius
Publicado 2013

Muscle-Specific IRS-1 Ser→Ala Transgenic Mice Are Protected From Fat-Induced Insulin Resistance in Skeletal Muscle

por Morino, Katsutaro, Neschen, Susanne, Bilz, Stefan, Sono, Saki, Tsirigotis, Dimitrios, Reznick, Richard M., Moore, Irene, Nagai, Yoshio, Samuel, Varman, Sebastian, David, White, Morris, Philbrick, William, Shulman, Gerald I.
Publicado 2008

Osteopontin deficiency protects against obesity-induced hepatic steatosis and attenuates glucose production in mice

por Kiefer, F. W., Neschen, S., Pfau, B., Legerer, B., Neuhofer, A., Kahle, M., Hrabé de Angelis, M., Schlederer, M., Mair, M., Kenner, L., Plutzky, J., Zeyda, M., Stulnig, T. M.
Publicado 2011

Bezafibrate ameliorates diabetes via reduced steatosis and improved hepatic insulin sensitivity in diabetic TallyHo mice

por Franko, Andras, Neschen, Susanne, Rozman, Jan, Rathkolb, Birgit, Aichler, Michaela, Feuchtinger, Annette, Brachthäuser, Laura, Neff, Frauke, Kovarova, Marketa, Wolf, Eckhard, Fuchs, Helmut, Häring, Hans-Ulrich, Peter, Andreas, Hrabě de Angelis, Martin
Publicado 2017

High fat diet-induced modifications in membrane lipid and mitochondrial-membrane protein signatures precede the development of hepatic insulin resistance in mice

por Kahle, M., Schäfer, A., Seelig, A., Schultheiß, J., Wu, M., Aichler, M., Leonhardt, J., Rathkolb, B., Rozman, J., Sarioglu, H., Hauck, S.M., Ueffing, M., Wolf, E., Kastenmueller, G., Adamski, J., Walch, A., Hrabé de Angelis, M., Neschen, S.
Publicado 2014

eIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcription

por Brina, Daniela, Miluzio, Annarita, Ricciardi, Sara, Clarke, Kim, Davidsen, Peter K., Viero, Gabriella, Tebaldi, Toma, Offenhäuser, Nina, Rozman, Jan, Rathkolb, Birgit, Neschen, Susanne, Klingenspor, Martin, Wolf, Eckhard, Gailus-Durner, Valerie, Fuchs, Helmut, Hrabe de Angelis, Martin, Quattrone, Alessandro, Falciani, Francesco, Biffo, Stefano
Publicado 2015

Validation of Candidate Phospholipid Biomarkers of Chronic Kidney Disease in Hyperglycemic Individuals and Their Organ-Specific Exploration in Leptin Receptor-Deficient db/db Mouse

por Huang, Jialing, Covic, Marcela, Huth, Cornelia, Rommel, Martina, Adam, Jonathan, Zukunft, Sven, Prehn, Cornelia, Wang, Li, Nano, Jana, Scheerer, Markus F., Neschen, Susanne, Kastenmüller, Gabi, Gieger, Christian, Laxy, Michael, Schliess, Freimut, Adamski, Jerzy, Suhre, Karsten, de Angelis, Martin Hrabe, Peters, Annette, Wang-Sattler, Rui
Publicado 2021

Irp2 regulates insulin production through iron-mediated Cdkal1-catalyzed tRNA modification

por Santos, Maria C. Ferreira dos, Anderson, Cole P., Neschen, Susanne, Zumbrennen-Bullough, Kimberly B., Romney, Steven J., Kahle-Stephan, Melanie, Rathkolb, Birgit, Gailus-Durner, Valerie, Fuchs, Helmut, Wolf, Eckhard, Rozman, Jan, de Angelis, Martin Hrabe, Cai, Weiling Maggie, Rajan, Malini, Hu, Jennifer, Dedon, Peter C., Leibold, Elizabeth A.
Publicado 2020

Innovations in phenotyping of mouse models in the German Mouse Clinic

por Fuchs, Helmut, Gailus-Durner, Valérie, Neschen, Susanne, Adler, Thure, Afonso, Luciana Caminha, Aguilar-Pimentel, Juan Antonio, Becker, Lore, Bohla, Alexander, Calzada-Wack, Julia, Cohrs, Christian, Dewert, Anna, Fridrich, Barbara, Garrett, Lillian, Glasl, Lisa, Götz, Alexander, Hans, Wolfgang, Hölter, Sabine M., Horsch, Marion, Hurt, Anja, Janas, Eva, Janik, Dirk, Kahle, Melanie, Kistler, Martin, Klein-Rodewald, Tanja, Lengger, Christoph, Ludwig, Tonia, Maier, Holger, Marschall, Susan, Micklich, Kateryna, Möller, Gabriele, Naton, Beatrix, Prehn, Cornelia, Puk, Oliver, Rácz, Ildikó, Räß, Michael, Rathkolb, Birgit, Rozman, Jan, Scheerer, Markus, Schiller, Evelyn, Schrewe, Anja, Steinkamp, Ralph, Stöger, Claudia, Sun, Minxuan, Szymczak, Wilfried, Treise, Irina, Vargas Panesso, Ingrid Liliana, Vernaleken, Alexandra M., Willershäuser, Monja, Wolff-Muscate, Annemarie, Zeh, Ramona, Adamski, Jerzy, Beckers, Johannes, Bekeredjian, Raffi, Busch, Dirk H., Eickelberg, Oliver, Favor, Jack, Graw, Jochen, Höfler, Heinz, Höschen, Christoph, Katus, Hugo, Klingenspor, Martin, Klopstock, Thomas, Neff, Frauke, Ollert, Markus, Schulz, Holger, Stöger, Tobias, Wolf, Eckhard, Wurst, Wolfgang, Yildirim, Ali Önder, Zimmer, Andreas, Hrabě de Angelis, Martin
Publicado 2012