A Glowing Opportunity to Target YAP in Lung Fibrosis

por Neubig, Richard R.
Publicado 2022

Role of Rho/MRTF in Aggressive Vemurafenib-Resistant Murine Melanomas and Immune Checkpoint Upregulation

por Foda, Bardees M., Neubig, Richard R.
Publicado 2023

FBXO44-Mediated Degradation of RGS2 Protein Uniquely Depends on a Cullin 4B/DDB1 Complex

por Sjögren, Benita, Swaney, Steven, Neubig, Richard R.
Publicado 2015

COVID-19—A Theory of Autoimmunity Against ACE-2 Explained

por McMillan, Philip, Dexhiemer, Thomas, Neubig, Richard R., Uhal, Bruce D.
Publicado 2021

The Rho/MRTF pathway inhibitor CCG-222740 reduces stellate cell activation and modulates immune cell populations in Kras(G12D); Pdx1-Cre (KC) mice

por Leal, Ana S., Misek, Sean A., Lisabeth, Erika M., Neubig, Richard R., Liby, Karen T.
Publicado 2019

Development of a Cell-Based AlphaLISA Assay for High-Throughput Screening for Small Molecule Proteasome Modulators

por Staerz, Sophia D., Lisabeth, Erika M., Njomen, Evert, Dexheimer, Thomas S., Neubig, Richard R., Tepe, Jetze J.
Publicado 2023

Mouse models of GNAO1-associated movement disorder: Allele- and sex-specific differences in phenotypes

por Feng, Huijie, Larrivee, Casandra L., Demireva, Elena Y., Xie, Huirong, Leipprandt, Jeff R., Neubig, Richard R.
Publicado 2019

Retraction: Mouse models of GNAO1-associated movement disorder: Allele- and sex-specific differences in phenotypes

por Feng, Huijie, Larrivee, Casandra L., Demireva, Elena Y., Xie, Huirong, Leipprandt, Jeff R., Neubig, Richard R.
Publicado 2021

Prevention of bleomycin‐induced lung fibrosis via inhibition of the MRTF/SRF transcription pathway

por Pawelec, Kendell M., Varnum, Megan, Harkema, Jack R., Auerbach, Bruce, Larsen, Scott D., Neubig, Richard R.
Publicado 2022

Increased CD39 Nucleotidase Activity on Microparticles from Patients with Idiopathic Pulmonary Arterial Hypertension

por Visovatti, Scott H., Hyman, Matthew C., Bouis, Diane, Neubig, Richard, McLaughlin, Vallerie V., Pinsky, David J.
Publicado 2012

Design and synthesis of tag-free photoprobes for the identification of the molecular target for CCG-1423, a novel inhibitor of the Rho/MKL1/SRF signaling pathway

por Bell, Jessica L, Haak, Andrew J, Wade, Susan M, Sun, Yihan, Neubig, Richard R, Larsen, Scott D
Publicado 2013

Identifying chemopreventive agents for obesity-associated cancers using an efficient, 3D high-throughput transformation assay

por Benham, Vanessa, Bullard, Blair, Dexheimer, Thomas S., Bernard, Matthew P., Neubig, Richard R., Liby, Karen T., Bernard, Jamie J.
Publicado 2019

Conditional disruption of interactions between Gα(i2) and regulator of G protein signaling (RGS) proteins protects the heart from ischemic injury

por Parra, Sergio, Huang, Xinyan, Charbeneau, Raelene A, Wade, Susan M, Kaur, Kuljeet, Rorabaugh, Boyd R, Neubig, Richard R
Publicado 2014

Phase-Locked Signals Elucidate Circuit Architecture of an Oscillatory Pathway

por Jovic, Andreja, Howell, Bryan, Cote, Michelle, Wade, Susan M., Mehta, Khamir, Miyawaki, Atsushi, Neubig, Richard R., Linderman, Jennifer J., Takayama, Shuichi
Publicado 2010

Small-Molecule Inhibition of Rho/MKL/SRF Transcription in Prostate Cancer Cells: Modulation of Cell Cycle, ER Stress, and Metastasis Gene Networks

por Evelyn, Chris R., Lisabeth, Erika M., Wade, Susan M., Haak, Andrew J., Johnson, Craig N., Lawlor, Elizabeth R., Neubig, Richard R.
Publicado 2016

Inhibition of the Myocardin-Related Transcription Factor Pathway Increases Efficacy of Trametinib in NRAS-Mutant Melanoma Cell Lines

por Appleton, Kathryn M., Palsuledesai, Charuta C., Misek, Sean A., Blake, Maja, Zagorski, Joseph, Gallo, Kathleen A., Dexheimer, Thomas S., Neubig, Richard R.
Publicado 2021

A covalent peptide inhibitor of RGS4 identified in a focused one-bead, one compound library screen

por Roof, Rebecca A, Roman, David L, Clements, Samuel T, Sobczyk-Kojiro, Katarzyna, Blazer, Levi L, Ota, Shodai, Mosberg, Henry I, Neubig, Richard R
Publicado 2009

BRAF Inhibitor Resistance Confers Increased Sensitivity to Mitotic Inhibitors

por Misek, Sean A., Foda, Bardees M., Dexheimer, Thomas S., Akram, Maisah, Conrad, Susan E., Schmidt, Jens C., Neubig, Richard R., Gallo, Kathleen A.
Publicado 2022

Gain-of-function mutation in Gnao1: A murine model of epileptiform encephalopathy (EIEE17)?

por Kehrl, Jason M., Sahaya, Kinshuk, Dalton, Hans M., Charbeneau, Raelene A., Kohut, Kevin T., Gilbert, Kristen, Pelz, Madeline C., Parent, Jack, Neubig, Richard R.
Publicado 2014

In vitro and in vivo delivery of a sustained release nanocarrier-based formulation of an MRTF/SRF inhibitor in conjunctival fibrosis

por Tagalakis, Aristides D., Madaan, Shivam, Larsen, Scott D., Neubig, Richard R., Khaw, Peng T., Rodrigues, Ian, Goyal, Saurabh, Lim, Kin Sheng, Yu-Wai-Man, Cynthia
Publicado 2018