Functional Mapping of Protein-Protein Interactions in an Enzyme Complex by Directed Evolution

por Roderer, Kathrin, Neuenschwander, Martin, Codoni, Giosiana, Sasso, Severin, Gamper, Marianne, Kast, Peter
Publicado 2014

Revealing cytotoxic substructures in molecules using deep learning

por Webel, Henry E., Kimber, Talia B., Radetzki, Silke, Neuenschwander, Martin, Nazaré, Marc, Volkamer, Andrea
Publicado 2020

Drug discovery with an RBM20 dependent titin splice reporter identifies cardenolides as lead structures to improve cardiac filling

por Liss, Martin, Radke, Michael H., Eckhard, Jamina, Neuenschwander, Martin, Dauksaite, Vita, von Kries, Jens-Peter, Gotthardt, Michael
Publicado 2018

Design of chemical libraries with potentially bioactive molecules applying a maximum common substructure concept

por Lisurek, Michael, Rupp, Bernd, Wichard, Jörg, Neuenschwander, Martin, von Kries, Jens Peter, Frank, Ronald, Rademann, Jörg, Kühne, Ronald
Publicado 2009

An unconventional gatekeeper mutation sensitizes inositol hexakisphosphate kinases to an allosteric inhibitor

por Aguirre, Tim, Dornan, Gillian L, Hostachy, Sarah, Neuenschwander, Martin, Seyffarth, Carola, Haucke, Volker, Schütz, Anja, von Kries, Jens Peter, Fiedler, Dorothea
Publicado 2023

Use of a sequential high throughput screening assay to identify novel inhibitors of the eukaryotic SRP-Sec61 targeting/translocation pathway

por Klein, Wolfgang, Rutz, Claudia, Eckhard, Jamina, Provinciael, Becky, Specker, Edgar, Neuenschwander, Martin, Kleinau, Gunnar, Scheerer, Patrick, von Kries, Jens-Peter, Nazaré, Marc, Vermeire, Kurt, Schülein, Ralf
Publicado 2018

Topical inflammasome inhibition with disulfiram prevents irritant contact dermatitis

por Bonnekoh, Hanna, Vera, Carolina, Abad‐Perez, Angela, Radetzki, Silke, Neuenschwander, Martin, Specker, Edgar, Mahnke, Niklas Amadeus, Frischbutter, Stefan, Latz, Eicke, Nazaré, Marc, Kries, Jens v., Maurer, Marcus, Scheffel, Jörg, Krause, Karoline
Publicado 2021

Statin and rottlerin small-molecule inhibitors restrict colon cancer progression and metastasis via MACC1

por Juneja, Manisha, Kobelt, Dennis, Walther, Wolfgang, Voss, Cynthia, Smith, Janice, Specker, Edgar, Neuenschwander, Martin, Gohlke, Björn-Oliver, Dahlmann, Mathias, Radetzki, Silke, Preissner, Robert, von Kries, Jens Peter, Schlag, Peter Michael, Stein, Ulrike
Publicado 2017

Small molecule inhibiting microglial nitric oxide release could become a potential treatment for neuroinflammation

por Jordan, Philipp, Costa, Amanda, Specker, Edgar, Popp, Oliver, Volkamer, Andrea, Piske, Regina, Obrusnik, Tessa, Kleissle, Sabrina, Stuke, Kevin, Rex, Andre, Neuenschwander, Martin, von Kries, Jens Peter, Nazare, Marc, Mertins, Phillip, Kettenmann, Helmut, Wolf, Susanne A.
Publicado 2023

Cyclin-Dependent Kinase 18 Controls Trafficking of Aquaporin-2 and Its Abundance through Ubiquitin Ligase STUB1, Which Functions as an AKAP

por Dema, Alessandro, Faust, Dörte, Lazarow, Katina, Wippich, Marc, Neuenschwander, Martin, Zühlke, Kerstin, Geelhaar, Andrea, Pallien, Tamara, Hallscheidt, Eileen, Eichhorst, Jenny, Wiesner, Burkhard, Černecká, Hana, Popp, Oliver, Mertins, Philipp, Dittmar, Gunnar, von Kries, Jens Peter, Klussmann, Enno
Publicado 2020

Loss-of-function uORF mutations in human malignancies

por Schulz, Julia, Mah, Nancy, Neuenschwander, Martin, Kischka, Tabea, Ratei, Richard, Schlag, Peter M., Castaños-Vélez, Esmeralda, Fichtner, Iduna, Tunn, Per-Ulf, Denkert, Carsten, Klaas, Oliver, Berdel, Wolfgang E., von Kries, Jens P., Makalowski, Wojciech, Andrade-Navarro, Miguel A., Leutz, Achim, Wethmar, Klaus
Publicado 2018

Author Correction: Loss-of-function uORF mutations in human malignancies

por Schulz, Julia, Mah, Nancy, Neuenschwander, Martin, Kischka, Tabea, Ratei, Richard, Schlag, Peter M., Castaños-Vélez, Esmeralda, Fichtner, Iduna, Tunn, Per-Ulf, Denkert, Carsten, Klaas, Oliver, Berdel, Wolfgang E., von Kries, Jens P., Makalowski, Wojciech, Andrade-Navarro, Miguel A., Leutz, Achim, Wethmar, Klaus
Publicado 2021

Glycolytic flux control by drugging phosphoglycolate phosphatase

por Jeanclos, Elisabeth, Schlötzer, Jan, Hadamek, Kerstin, Yuan-Chen, Natalia, Alwahsh, Mohammad, Hollmann, Robert, Fratz, Stefanie, Yesilyurt-Gerhards, Dilan, Frankenbach, Tina, Engelmann, Daria, Keller, Angelika, Kaestner, Alexandra, Schmitz, Werner, Neuenschwander, Martin, Hergenröder, Roland, Sotriffer, Christoph, von Kries, Jens Peter, Schindelin, Hermann, Gohla, Antje
Publicado 2022

Pentafluorosulfanyl (SF(5)) as a Superior (19)F Magnetic Resonance Reporter Group: Signal Detection and Biological Activity of Teriflunomide Derivatives

por Prinz, Christian, Starke, Ludger, Ramspoth, Tizian-Frank, Kerkering, Janis, Martos Riaño, Vera, Paul, Jérôme, Neuenschwander, Martin, Oder, Andreas, Radetzki, Silke, Adelhoefer, Siegfried, Ramos Delgado, Paula, Aravina, Mariya, Millward, Jason M., Fillmer, Ariane, Paul, Friedemann, Siffrin, Volker, von Kries, Jens-Peter, Niendorf, Thoralf, Nazaré, Marc, Waiczies, Sonia
Publicado 2021

Development of selective inhibitors of phosphatidylinositol 3-kinase C2α

por Lo, Wen-Ting, Belabed, Hassane, Kücükdisli, Murat, Metag, Juliane, Roske, Yvette, Prokofeva, Polina, Ohashi, Yohei, Horatscheck, André, Cirillo, Davide, Krauss, Michael, Schmied, Christopher, Neuenschwander, Martin, von Kries, Jens Peter, Médard, Guillaume, Kuster, Bernhard, Perisic, Olga, Williams, Roger L., Daumke, Oliver, Payrastre, Bernard, Severin, Sonia, Nazaré, Marc, Haucke, Volker
Publicado 2022

Systematic pharmacological screens uncover novel pathways involved in cerebral cavernous malformations

por Otten, Cécile, Knox, Jessica, Boulday, Gwénola, Eymery, Mathias, Haniszewski, Marta, Neuenschwander, Martin, Radetzki, Silke, Vogt, Ingo, Hähn, Kristina, De Luca, Coralie, Cardoso, Cécile, Hamad, Sabri, Igual Gil, Carla, Roy, Peter, Albiges‐Rizo, Corinne, Faurobert, Eva, von Kries, Jens P, Campillos, Mónica, Tournier‐Lasserve, Elisabeth, Derry, W Brent, Abdelilah‐Seyfried, Salim
Publicado 2018

An AKAP-Lbc-RhoA interaction inhibitor promotes the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells

por Schrade, Katharina, Tröger, Jessica, Eldahshan, Adeeb, Zühlke, Kerstin, Abdul Azeez, Kamal R., Elkins, Jonathan M., Neuenschwander, Martin, Oder, Andreas, Elkewedi, Mohamed, Jaksch, Sarah, Andrae, Karsten, Li, Jinliang, Fernandes, Joao, Müller, Paul Markus, Grunwald, Stephan, Marino, Stephen F., Vukićević, Tanja, Eichhorst, Jenny, Wiesner, Burkhard, Weber, Marcus, Kapiloff, Michael, Rocks, Oliver, Daumke, Oliver, Wieland, Thomas, Knapp, Stefan, von Kries, Jens Peter, Klussmann, Enno
Publicado 2018

EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology

por Brennecke, Philip, Rasina, Dace, Aubi, Oscar, Herzog, Katja, Landskron, Johannes, Cautain, Bastien, Vicente, Francisca, Quintana, Jordi, Mestres, Jordi, Stechmann, Bahne, Ellinger, Bernhard, Brea, Jose, Kolanowski, Jacek L., Pilarski, Radosław, Orzaez, Mar, Pineda-Lucena, Antonio, Laraia, Luca, Nami, Faranak, Zielenkiewicz, Piotr, Paruch, Kamil, Hansen, Espen, von Kries, Jens P., Neuenschwander, Martin, Specker, Edgar, Bartunek, Petr, Simova, Sarka, Leśnikowski, Zbigniew, Krauss, Stefan, Lehtiö, Lari, Bilitewski, Ursula, Brönstrup, Mark, Taskén, Kjetil, Jirgensons, Aigars, Lickert, Heiko, Clausen, Mads H., Andersen, Jeanette H., Vicent, Maria J., Genilloud, Olga, Martinez, Aurora, Nazaré, Marc, Fecke, Wolfgang, Gribbon, Philip
Publicado 2019